Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mazEF/PemK-MazE |
Location | 2932466..2933010 | Replicon | chromosome |
Accession | NZ_AP023268 | ||
Organism | Agrobacterium vitis strain VAR03-1 |
Toxin (Protein)
Gene name | mazF | Uniprot ID | - |
Locus tag | RvVAT039_RS13515 | Protein ID | WP_180637958.1 |
Coordinates | 2932687..2933010 (+) | Length | 108 a.a. |
Antitoxin (Protein)
Gene name | mazE | Uniprot ID | - |
Locus tag | RvVAT039_RS13510 | Protein ID | WP_180637956.1 |
Coordinates | 2932466..2932690 (+) | Length | 75 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
RvVAT039_RS13480 | 2927547..2928365 | + | 819 | WP_015916803.1 | ABC transporter ATP-binding protein | - |
RvVAT039_RS13485 | 2928379..2929272 | + | 894 | WP_180637946.1 | ABC transporter permease | - |
RvVAT039_RS13490 | 2929508..2930173 | + | 666 | WP_180637948.1 | hypothetical protein | - |
RvVAT039_RS13495 | 2930434..2931438 | + | 1005 | WP_180637950.1 | hypothetical protein | - |
RvVAT039_RS13500 | 2931435..2931764 | + | 330 | WP_180637952.1 | hypothetical protein | - |
RvVAT039_RS13505 | 2931761..2932192 | + | 432 | WP_180637954.1 | hypothetical protein | - |
RvVAT039_RS13510 | 2932466..2932690 | + | 225 | WP_180637956.1 | antitoxin MazE family protein | Antitoxin |
RvVAT039_RS13515 | 2932687..2933010 | + | 324 | WP_180637958.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
RvVAT039_RS13520 | 2933031..2934452 | - | 1422 | WP_180637960.1 | sensor histidine kinase | - |
RvVAT039_RS13525 | 2934486..2935151 | - | 666 | WP_060717790.1 | response regulator | - |
RvVAT039_RS13530 | 2935251..2935997 | - | 747 | WP_180637962.1 | metallophosphatase family protein | - |
RvVAT039_RS13535 | 2936001..2936357 | - | 357 | WP_070149013.1 | hydroxyisourate hydrolase | - |
RvVAT039_RS13540 | 2936354..2936866 | - | 513 | WP_180637965.1 | ureidoglycolate lyase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 108 a.a. Molecular weight: 11412.32 Da Isoelectric Point: 10.7588
>T37141 WP_180637958.1 NZ_AP023268:2932687-2933010 [Agrobacterium vitis]
VKRGDLVTVAVPGDFGKPRPALIIQSDFFSETGTATVLLISSTLVDAPLLRVTMQPSSANGLKKPSQIMVDKAISIRRER
LGPASGRLDDDTMLSVKRSLAVFFGIG
VKRGDLVTVAVPGDFGKPRPALIIQSDFFSETGTATVLLISSTLVDAPLLRVTMQPSSANGLKKPSQIMVDKAISIRRER
LGPASGRLDDDTMLSVKRSLAVFFGIG
Download Length: 324 bp
>T37141 NZ_AP023268:2932687-2933010 [Agrobacterium vitis]
GTGAAGCGGGGCGATCTGGTGACGGTCGCCGTGCCCGGCGACTTTGGTAAGCCGCGCCCTGCCCTTATCATTCAATCGGA
CTTTTTCTCTGAAACCGGCACCGCAACCGTGTTGCTGATCTCCTCCACGCTCGTCGATGCGCCGCTGCTGCGGGTGACGA
TGCAGCCGTCGTCTGCCAATGGCTTGAAAAAGCCATCACAGATCATGGTGGACAAAGCCATATCGATCAGGCGAGAACGG
CTTGGCCCCGCCTCCGGTCGGTTGGATGATGACACCATGCTGTCCGTGAAACGTTCGCTGGCTGTGTTTTTCGGCATTGG
CTGA
GTGAAGCGGGGCGATCTGGTGACGGTCGCCGTGCCCGGCGACTTTGGTAAGCCGCGCCCTGCCCTTATCATTCAATCGGA
CTTTTTCTCTGAAACCGGCACCGCAACCGTGTTGCTGATCTCCTCCACGCTCGTCGATGCGCCGCTGCTGCGGGTGACGA
TGCAGCCGTCGTCTGCCAATGGCTTGAAAAAGCCATCACAGATCATGGTGGACAAAGCCATATCGATCAGGCGAGAACGG
CTTGGCCCCGCCTCCGGTCGGTTGGATGATGACACCATGCTGTCCGTGAAACGTTCGCTGGCTGTGTTTTTCGGCATTGG
CTGA
Antitoxin
Download Length: 75 a.a. Molecular weight: 8286.34 Da Isoelectric Point: 4.7182
>AT37141 WP_180637956.1 NZ_AP023268:2932466-2932690 [Agrobacterium vitis]
MPTPVNHRVQKRRDALRAAGLRPVQIWVPDTRRPGFIEECHRQSMAVAAVDGADGDVLGFMDDALVDLDNEYPE
MPTPVNHRVQKRRDALRAAGLRPVQIWVPDTRRPGFIEECHRQSMAVAAVDGADGDVLGFMDDALVDLDNEYPE
Download Length: 225 bp
>AT37141 NZ_AP023268:2932466-2932690 [Agrobacterium vitis]
ATGCCAACACCCGTCAATCATCGTGTACAAAAACGGCGCGATGCCTTGCGCGCTGCGGGGTTGCGACCTGTGCAAATTTG
GGTGCCGGATACGCGTCGGCCTGGTTTTATCGAGGAATGCCATCGTCAATCCATGGCGGTCGCGGCTGTCGATGGGGCTG
ATGGTGATGTTCTGGGTTTCATGGATGATGCTCTGGTCGATCTCGATAACGAGTATCCCGAGTGA
ATGCCAACACCCGTCAATCATCGTGTACAAAAACGGCGCGATGCCTTGCGCGCTGCGGGGTTGCGACCTGTGCAAATTTG
GGTGCCGGATACGCGTCGGCCTGGTTTTATCGAGGAATGCCATCGTCAATCCATGGCGGTCGCGGCTGTCGATGGGGCTG
ATGGTGATGTTCTGGGTTTCATGGATGATGCTCTGGTCGATCTCGATAACGAGTATCCCGAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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