Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 2932466..2933010 Replicon chromosome
Accession NZ_AP023268
Organism Agrobacterium vitis strain VAR03-1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag RvVAT039_RS13515 Protein ID WP_180637958.1
Coordinates 2932687..2933010 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag RvVAT039_RS13510 Protein ID WP_180637956.1
Coordinates 2932466..2932690 (+) Length 75 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RvVAT039_RS13480 2927547..2928365 + 819 WP_015916803.1 ABC transporter ATP-binding protein -
RvVAT039_RS13485 2928379..2929272 + 894 WP_180637946.1 ABC transporter permease -
RvVAT039_RS13490 2929508..2930173 + 666 WP_180637948.1 hypothetical protein -
RvVAT039_RS13495 2930434..2931438 + 1005 WP_180637950.1 hypothetical protein -
RvVAT039_RS13500 2931435..2931764 + 330 WP_180637952.1 hypothetical protein -
RvVAT039_RS13505 2931761..2932192 + 432 WP_180637954.1 hypothetical protein -
RvVAT039_RS13510 2932466..2932690 + 225 WP_180637956.1 antitoxin MazE family protein Antitoxin
RvVAT039_RS13515 2932687..2933010 + 324 WP_180637958.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
RvVAT039_RS13520 2933031..2934452 - 1422 WP_180637960.1 sensor histidine kinase -
RvVAT039_RS13525 2934486..2935151 - 666 WP_060717790.1 response regulator -
RvVAT039_RS13530 2935251..2935997 - 747 WP_180637962.1 metallophosphatase family protein -
RvVAT039_RS13535 2936001..2936357 - 357 WP_070149013.1 hydroxyisourate hydrolase -
RvVAT039_RS13540 2936354..2936866 - 513 WP_180637965.1 ureidoglycolate lyase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-104)

Antitoxin

(6-70)


Sequences


Toxin        


Download         Length: 108 a.a.        Molecular weight: 11412.32 Da        Isoelectric Point: 10.7588

>T37141 WP_180637958.1 NZ_AP023268:2932687-2933010 [Agrobacterium vitis]
VKRGDLVTVAVPGDFGKPRPALIIQSDFFSETGTATVLLISSTLVDAPLLRVTMQPSSANGLKKPSQIMVDKAISIRRER
LGPASGRLDDDTMLSVKRSLAVFFGIG

Download         Length: 324 bp

>T37141 NZ_AP023268:2932687-2933010 [Agrobacterium vitis]
GTGAAGCGGGGCGATCTGGTGACGGTCGCCGTGCCCGGCGACTTTGGTAAGCCGCGCCCTGCCCTTATCATTCAATCGGA
CTTTTTCTCTGAAACCGGCACCGCAACCGTGTTGCTGATCTCCTCCACGCTCGTCGATGCGCCGCTGCTGCGGGTGACGA
TGCAGCCGTCGTCTGCCAATGGCTTGAAAAAGCCATCACAGATCATGGTGGACAAAGCCATATCGATCAGGCGAGAACGG
CTTGGCCCCGCCTCCGGTCGGTTGGATGATGACACCATGCTGTCCGTGAAACGTTCGCTGGCTGTGTTTTTCGGCATTGG
CTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8286.34 Da        Isoelectric Point: 4.7182

>AT37141 WP_180637956.1 NZ_AP023268:2932466-2932690 [Agrobacterium vitis]
MPTPVNHRVQKRRDALRAAGLRPVQIWVPDTRRPGFIEECHRQSMAVAAVDGADGDVLGFMDDALVDLDNEYPE

Download         Length: 225 bp

>AT37141 NZ_AP023268:2932466-2932690 [Agrobacterium vitis]
ATGCCAACACCCGTCAATCATCGTGTACAAAAACGGCGCGATGCCTTGCGCGCTGCGGGGTTGCGACCTGTGCAAATTTG
GGTGCCGGATACGCGTCGGCCTGGTTTTATCGAGGAATGCCATCGTCAATCCATGGCGGTCGCGGCTGTCGATGGGGCTG
ATGGTGATGTTCTGGGTTTCATGGATGATGCTCTGGTCGATCTCGATAACGAGTATCCCGAGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References