Detailed information of TA system TA037139

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/CC2985(antitoxin)
• Location: 2443171..2443712
• Replicon: chromosome
• Accession: NZ_AP023268
• Organism: Agrobacterium vitis strain VAR03-1

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: RvVAT039_RS11280
• Protein ID: WP_180637725.1
• Coordinates: 2443530..2443712 (+)
• Length: 61 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: RvVAT039_RS11275
• Protein ID: WP_180637724.1
• Coordinates: 2443171..2443419 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RvVAT039_RS11260	2438972..2439619	-	648	WP_180640725.1	precorrin-8X methylmutase	-
RvVAT039_RS11265	2440639..2441985	-	1347	WP_180637722.1	sirohydrochlorin chelatase	-
RvVAT039_RS11270	2442321..2443106	+	786	WP_180637723.1	TSUP family transporter	-
RvVAT039_RS11275	2443171..2443419	+	249	WP_180637724.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
RvVAT039_RS11280	2443530..2443712	+	183	WP_180637725.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
RvVAT039_RS11285	2443781..2444425	-	645	WP_180637726.1	cob(I)yrinic acid a,c-diamide adenosyltransferase	-
RvVAT039_RS11290	2444422..2448189	-	3768	WP_180637727.1	cobaltochelatase subunit CobN	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-55)

Antitoxin

• Antitoxin ParD (3-72)

Sequences

Toxin

Protein

• Length: 61 a.a.
• Molecular weight: 7042.03 Da
• Isoelectric Point: 6.8773

>T37139 WP_180637725.1 NZ_AP023268:2443530-2443712 [Agrobacterium vitis]
MFSRFEFLAEFPYSGQKHDHIREGLFGFSEGAHVIFYRINADGIDIVRVLHQRMSLEGRL

Nucleotide

• Length: 183 bp

>T37139 NZ_AP023268:2443530-2443712 [Agrobacterium vitis]
TTGTTCAGCAGGTTCGAGTTTCTCGCTGAATTTCCCTATTCTGGACAAAAGCATGACCACATCAGGGAAGGCCTTTTCGG
TTTTTCCGAGGGCGCGCACGTGATCTTTTACCGGATCAATGCCGATGGCATCGACATCGTCCGTGTCCTTCACCAGCGCA
TGAGCCTGGAAGGGCGACTGTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9488.55 Da
• Isoelectric Point: 4.8893

>AT37139 WP_180637724.1 NZ_AP023268:2443171-2443419 [Agrobacterium vitis]
MATTSLTLGPHCEGFIKQQISSGRYASASEVVRDALRELEEREEKLKILRHQIDKGWQQADRGEFAEDWSLQSLNEKLDR
EQ

Nucleotide

• Length: 249 bp

>AT37139 NZ_AP023268:2443171-2443419 [Agrobacterium vitis]
ATGGCAACAACCAGCCTGACACTTGGCCCGCATTGTGAAGGCTTCATCAAGCAGCAGATAAGCAGTGGCCGCTACGCCTC
TGCGAGCGAAGTGGTGCGAGACGCGCTCCGCGAGTTGGAGGAGCGGGAAGAAAAGCTGAAAATTTTGCGCCATCAGATCG
ACAAGGGTTGGCAACAAGCAGATCGTGGAGAGTTTGCAGAGGATTGGTCGCTCCAATCACTCAATGAAAAACTCGACCGC
GAACAATGA