Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-VagC
Location 1586882..1587567 Replicon chromosome
Accession NZ_AP023268
Organism Agrobacterium vitis strain VAR03-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RvVAT039_RS07225 Protein ID WP_180640521.1
Coordinates 1586882..1587298 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag RvVAT039_RS07230 Protein ID WP_197970828.1
Coordinates 1587298..1587567 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RvVAT039_RS07200 1582607..1584223 - 1617 WP_180640510.1 citramalate synthase -
RvVAT039_RS07205 1584468..1585424 - 957 WP_180640512.1 prolyl aminopeptidase -
RvVAT039_RS07210 1585417..1585929 - 513 WP_180640514.1 GFA family protein -
RvVAT039_RS07215 1585926..1586393 - 468 WP_180640516.1 GFA family protein -
RvVAT039_RS07220 1586390..1586878 - 489 WP_180640519.1 GFA family protein -
RvVAT039_RS07225 1586882..1587298 - 417 WP_180640521.1 type II toxin-antitoxin system VapC family toxin Toxin
RvVAT039_RS07230 1587298..1587567 - 270 WP_197970828.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
RvVAT039_RS07235 1587614..1589023 - 1410 WP_180640523.1 cysteine--tRNA ligase -
RvVAT039_RS07240 1589368..1591002 + 1635 WP_180640525.1 glycoside hydrolase family 28 protein -
RvVAT039_RS07245 1591186..1591749 + 564 WP_015915489.1 dTDP-4-dehydrorhamnose 3,5-epimerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-121)

Antitoxin

SpoVT-AbrB domain

(16-53)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15417.54 Da        Isoelectric Point: 5.1993

>T37138 WP_180640521.1 NZ_AP023268:c1587298-1586882 [Agrobacterium vitis]
MGFMLDTNIVSDMVRNPDGPAMERWKQTGYADLHLSAIVVSELYFGIQKRESERLRRGVETFLNTVVIEAFEGRAAHYYA
SIRNALAKAGEMIGPNDLFIAAHALSLDMVLVTNNTREFAGVSGLKLENWLETTHEGQ

Download         Length: 417 bp

>T37138 NZ_AP023268:c1587298-1586882 [Agrobacterium vitis]
ATGGGATTTATGTTGGATACCAATATCGTCTCCGACATGGTTCGAAATCCTGATGGGCCTGCCATGGAACGCTGGAAACA
AACAGGCTATGCGGACCTGCATCTCAGCGCCATCGTCGTCTCCGAACTCTACTTTGGTATCCAAAAGCGTGAGTCGGAGC
GATTGCGACGGGGTGTTGAGACGTTTCTGAACACTGTTGTGATCGAGGCTTTCGAGGGGCGCGCTGCCCATTATTATGCC
AGCATTCGCAACGCTCTGGCAAAGGCTGGCGAGATGATTGGTCCCAACGACCTGTTCATTGCCGCCCACGCGCTGTCATT
GGATATGGTTCTGGTCACCAACAATACCCGCGAATTTGCCGGTGTATCCGGGCTGAAACTGGAAAACTGGCTCGAAACCA
CACATGAGGGGCAATAG

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10304.88 Da        Isoelectric Point: 5.2457

>AT37138 WP_197970828.1 NZ_AP023268:c1587567-1587298 [Agrobacterium vitis]
MEANMSVEQERHVRVFKNGRNRAVRIPVEFEFPGDEVIMRKEGDRIIIEPVGSTRKKENLVAFLRKQGKIEDDFPDVDEG
LLPLKDVIL

Download         Length: 270 bp

>AT37138 NZ_AP023268:c1587567-1587298 [Agrobacterium vitis]
ATGGAGGCAAATATGAGTGTGGAGCAGGAAAGACATGTGCGGGTGTTCAAGAATGGTCGCAATCGCGCCGTTCGCATCCC
CGTGGAATTCGAGTTTCCGGGCGATGAAGTGATCATGCGCAAGGAAGGCGATCGGATCATTATCGAGCCTGTTGGCAGTA
CCCGGAAAAAGGAAAATCTGGTCGCTTTTCTGAGGAAACAGGGGAAAATAGAGGATGATTTTCCCGATGTGGATGAAGGA
CTGCTTCCTTTGAAGGATGTCATCCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References