Detailed information of TA system TA037137

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/LOTUS_5_Limkain_b1(toxin)
• Location: 1322902..1323473
• Replicon: chromosome
• Accession: NZ_AP023268
• Organism: Agrobacterium vitis strain VAR03-1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: RvVAT039_RS05985
• Protein ID: WP_180640265.1
• Coordinates: 1323108..1323473 (+)
• Length: 122 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: RvVAT039_RS05980
• Protein ID: WP_180640263.1
• Coordinates: 1322902..1323114 (+)
• Length: 71 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RvVAT039_RS05965	1318939..1319904	+	966	WP_180640259.1	flagellin	-
RvVAT039_RS05970	1319908..1321230	-	1323	WP_180640676.1	chloride channel protein	-
RvVAT039_RS05975	1321540..1322829	+	1290	WP_180640261.1	DUF2156 domain-containing protein	-
RvVAT039_RS05980	1322902..1323114	+	213	WP_180640263.1	ribbon-helix-helix domain-containing protein	Antitoxin
RvVAT039_RS05985	1323108..1323473	+	366	WP_180640265.1	type II toxin-antitoxin system VapC family toxin	Toxin
RvVAT039_RS05990	1323478..1325130	-	1653	WP_180640267.1	choline dehydrogenase	-
RvVAT039_RS05995	1325370..1326833	-	1464	WP_180640677.1	betaine-aldehyde dehydrogenase	-
RvVAT039_RS06000	1326833..1327474	-	642	WP_156543511.1	glutathione S-transferase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-106)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-40)

Sequences

Toxin

Protein

• Length: 122 a.a.
• Molecular weight: 13562.76 Da
• Isoelectric Point: 7.2785

>T37137 WP_180640265.1 NZ_AP023268:1323108-1323473 [Agrobacterium vitis]
MVKALFDTNILIDFLNGKEPARQELSLYEEKAISMVTWMEVMVGASDENGQATAAFLRSFRCIAIDQTVAERAVALRRAH
RLKLPDAIVWASALAHDMVLVTRDTKDLPGNHPGIRIPYRL

Nucleotide

• Length: 366 bp

>T37137 NZ_AP023268:1323108-1323473 [Agrobacterium vitis]
ATGGTAAAAGCGCTGTTCGATACCAATATCCTGATCGATTTTCTGAACGGCAAGGAACCAGCCAGGCAGGAGCTTTCGCT
TTACGAGGAGAAGGCGATCAGCATGGTGACCTGGATGGAGGTTATGGTTGGAGCATCCGATGAGAACGGGCAGGCGACCG
CTGCATTTCTGCGCAGTTTTCGCTGCATCGCCATCGATCAGACCGTAGCCGAACGTGCAGTTGCCTTGAGGCGTGCGCAT
CGGCTGAAACTGCCTGACGCGATTGTCTGGGCAAGTGCTCTGGCCCATGACATGGTGCTGGTAACCCGCGATACCAAGGA
CTTGCCGGGCAACCATCCCGGCATCCGCATTCCCTATCGGCTGTGA

Antitoxin

Protein

• Length: 71 a.a.
• Molecular weight: 8101.11 Da
• Isoelectric Point: 4.5238

>AT37137 WP_180640263.1 NZ_AP023268:1322902-1323114 [Agrobacterium vitis]
MRTLIDLEDDAVVELDRIARQEKVSRAALIRQAVASLLEQRQQPDLDHGFGLWKNQPDGLAYQQALRDEW

Nucleotide

• Length: 213 bp

>AT37137 NZ_AP023268:1322902-1323114 [Agrobacterium vitis]
ATGAGAACATTGATCGACCTTGAGGACGATGCCGTTGTGGAACTGGACCGGATTGCCCGCCAGGAAAAAGTTTCCCGGGC
AGCGTTGATCCGGCAGGCCGTGGCATCTTTGCTGGAACAACGGCAGCAGCCTGATTTGGACCACGGCTTTGGTCTCTGGA
AAAACCAGCCTGATGGCCTTGCCTATCAGCAAGCCCTGCGCGACGAATGGTAA