Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/PIN(toxin) |
Location | 6010689..6011350 | Replicon | chromosome |
Accession | NZ_AP023263 | ||
Organism | Mesorhizobium sp. L-8-10 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | JN280_RS28155 | Protein ID | WP_202307210.1 |
Coordinates | 6010913..6011350 (+) | Length | 146 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | JN280_RS28150 | Protein ID | WP_202307208.1 |
Coordinates | 6010689..6010916 (+) | Length | 76 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JN280_RS28135 | 6005881..6007515 | - | 1635 | WP_202307202.1 | tryptophan 7-halogenase | - |
JN280_RS28140 | 6008001..6009617 | - | 1617 | WP_202307204.1 | MFS transporter | - |
JN280_RS28145 | 6009877..6010341 | - | 465 | WP_202307206.1 | transcriptional regulator NrdR | - |
JN280_RS28150 | 6010689..6010916 | + | 228 | WP_202307208.1 | ribbon-helix-helix domain-containing protein | Antitoxin |
JN280_RS28155 | 6010913..6011350 | + | 438 | WP_202307210.1 | PIN domain-containing protein | Toxin |
JN280_RS28160 | 6011473..6011829 | - | 357 | Protein_5586 | transcriptional repressor NrdR | - |
JN280_RS28165 | 6011949..6013265 | - | 1317 | WP_202307212.1 | serine hydroxymethyltransferase | - |
JN280_RS28170 | 6013475..6014728 | - | 1254 | WP_202307214.1 | L,D-transpeptidase family protein | - |
JN280_RS28175 | 6015045..6015560 | - | 516 | WP_202307217.1 | winged helix DNA-binding protein | - |
JN280_RS28180 | 6015871..6016299 | - | 429 | WP_202307221.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 146 a.a. Molecular weight: 15688.92 Da Isoelectric Point: 7.4208
>T37134 WP_202307210.1 NZ_AP023263:6010913-6011350 [Mesorhizobium sp. L-8-10]
VIYLLDVNVLIALIDPGHIAHDDAHRWFELAGQASWATCPITENGVMRIVGSPKYPNSPGSPPLVADIVKRLRALPGHQF
WPDDASLVSSRDIDTDRIRTSAQVTDTYLLSLAKSNGGQLATFDRKLSPDAVKGGKAALHLIPSK
VIYLLDVNVLIALIDPGHIAHDDAHRWFELAGQASWATCPITENGVMRIVGSPKYPNSPGSPPLVADIVKRLRALPGHQF
WPDDASLVSSRDIDTDRIRTSAQVTDTYLLSLAKSNGGQLATFDRKLSPDAVKGGKAALHLIPSK
Download Length: 438 bp
>T37134 NZ_AP023263:6010913-6011350 [Mesorhizobium sp. L-8-10]
GTGATCTATCTGCTTGACGTCAATGTGCTAATCGCACTGATCGATCCGGGTCACATTGCTCACGACGACGCTCATCGGTG
GTTCGAATTGGCAGGGCAAGCGTCTTGGGCAACTTGTCCCATAACCGAGAATGGGGTCATGCGGATTGTCGGCAGTCCAA
AGTACCCAAACTCTCCAGGCTCTCCCCCCCTCGTCGCAGACATCGTCAAGAGGTTGCGGGCGCTTCCCGGGCACCAGTTT
TGGCCCGATGATGCAAGCCTTGTCAGTTCACGTGACATTGATACCGACAGAATCCGGACCTCTGCGCAGGTGACCGATAC
CTATCTGCTATCGCTCGCCAAGTCCAACGGGGGCCAACTCGCAACCTTTGACCGTAAATTGTCACCTGATGCGGTAAAAG
GTGGAAAGGCTGCGCTCCATCTGATTCCGAGCAAGTAA
GTGATCTATCTGCTTGACGTCAATGTGCTAATCGCACTGATCGATCCGGGTCACATTGCTCACGACGACGCTCATCGGTG
GTTCGAATTGGCAGGGCAAGCGTCTTGGGCAACTTGTCCCATAACCGAGAATGGGGTCATGCGGATTGTCGGCAGTCCAA
AGTACCCAAACTCTCCAGGCTCTCCCCCCCTCGTCGCAGACATCGTCAAGAGGTTGCGGGCGCTTCCCGGGCACCAGTTT
TGGCCCGATGATGCAAGCCTTGTCAGTTCACGTGACATTGATACCGACAGAATCCGGACCTCTGCGCAGGTGACCGATAC
CTATCTGCTATCGCTCGCCAAGTCCAACGGGGGCCAACTCGCAACCTTTGACCGTAAATTGTCACCTGATGCGGTAAAAG
GTGGAAAGGCTGCGCTCCATCTGATTCCGAGCAAGTAA
Antitoxin
Download Length: 76 a.a. Molecular weight: 8366.57 Da Isoelectric Point: 6.3147
>AT37134 WP_202307208.1 NZ_AP023263:6010689-6010916 [Mesorhizobium sp. L-8-10]
MRTTLAIDDDVLVAAKAMARQQDRSLGEVISELARRSLRRPRIGGERNGIPLLSPRPDSPPVTLEFVNELRDELS
MRTTLAIDDDVLVAAKAMARQQDRSLGEVISELARRSLRRPRIGGERNGIPLLSPRPDSPPVTLEFVNELRDELS
Download Length: 228 bp
>AT37134 NZ_AP023263:6010689-6010916 [Mesorhizobium sp. L-8-10]
ATGCGAACGACACTGGCGATTGACGATGATGTTCTGGTCGCGGCCAAGGCGATGGCCCGGCAGCAGGACCGAAGCCTCGG
AGAGGTGATCTCCGAGTTGGCGCGGCGTTCCTTGCGCAGGCCGAGGATCGGCGGCGAACGCAATGGCATTCCGCTGTTGT
CGCCCCGCCCCGACAGCCCCCCCGTTACGCTAGAGTTCGTCAATGAATTGCGCGACGAACTTTCGTGA
ATGCGAACGACACTGGCGATTGACGATGATGTTCTGGTCGCGGCCAAGGCGATGGCCCGGCAGCAGGACCGAAGCCTCGG
AGAGGTGATCTCCGAGTTGGCGCGGCGTTCCTTGCGCAGGCCGAGGATCGGCGGCGAACGCAATGGCATTCCGCTGTTGT
CGCCCCGCCCCGACAGCCCCCCCGTTACGCTAGAGTTCGTCAATGAATTGCGCGACGAACTTTCGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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