Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 6010689..6011350 Replicon chromosome
Accession NZ_AP023263
Organism Mesorhizobium sp. L-8-10

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JN280_RS28155 Protein ID WP_202307210.1
Coordinates 6010913..6011350 (+) Length 146 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JN280_RS28150 Protein ID WP_202307208.1
Coordinates 6010689..6010916 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN280_RS28135 6005881..6007515 - 1635 WP_202307202.1 tryptophan 7-halogenase -
JN280_RS28140 6008001..6009617 - 1617 WP_202307204.1 MFS transporter -
JN280_RS28145 6009877..6010341 - 465 WP_202307206.1 transcriptional regulator NrdR -
JN280_RS28150 6010689..6010916 + 228 WP_202307208.1 ribbon-helix-helix domain-containing protein Antitoxin
JN280_RS28155 6010913..6011350 + 438 WP_202307210.1 PIN domain-containing protein Toxin
JN280_RS28160 6011473..6011829 - 357 Protein_5586 transcriptional repressor NrdR -
JN280_RS28165 6011949..6013265 - 1317 WP_202307212.1 serine hydroxymethyltransferase -
JN280_RS28170 6013475..6014728 - 1254 WP_202307214.1 L,D-transpeptidase family protein -
JN280_RS28175 6015045..6015560 - 516 WP_202307217.1 winged helix DNA-binding protein -
JN280_RS28180 6015871..6016299 - 429 WP_202307221.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15688.92 Da        Isoelectric Point: 7.4208

>T37134 WP_202307210.1 NZ_AP023263:6010913-6011350 [Mesorhizobium sp. L-8-10]
VIYLLDVNVLIALIDPGHIAHDDAHRWFELAGQASWATCPITENGVMRIVGSPKYPNSPGSPPLVADIVKRLRALPGHQF
WPDDASLVSSRDIDTDRIRTSAQVTDTYLLSLAKSNGGQLATFDRKLSPDAVKGGKAALHLIPSK

Download         Length: 438 bp

>T37134 NZ_AP023263:6010913-6011350 [Mesorhizobium sp. L-8-10]
GTGATCTATCTGCTTGACGTCAATGTGCTAATCGCACTGATCGATCCGGGTCACATTGCTCACGACGACGCTCATCGGTG
GTTCGAATTGGCAGGGCAAGCGTCTTGGGCAACTTGTCCCATAACCGAGAATGGGGTCATGCGGATTGTCGGCAGTCCAA
AGTACCCAAACTCTCCAGGCTCTCCCCCCCTCGTCGCAGACATCGTCAAGAGGTTGCGGGCGCTTCCCGGGCACCAGTTT
TGGCCCGATGATGCAAGCCTTGTCAGTTCACGTGACATTGATACCGACAGAATCCGGACCTCTGCGCAGGTGACCGATAC
CTATCTGCTATCGCTCGCCAAGTCCAACGGGGGCCAACTCGCAACCTTTGACCGTAAATTGTCACCTGATGCGGTAAAAG
GTGGAAAGGCTGCGCTCCATCTGATTCCGAGCAAGTAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8366.57 Da        Isoelectric Point: 6.3147

>AT37134 WP_202307208.1 NZ_AP023263:6010689-6010916 [Mesorhizobium sp. L-8-10]
MRTTLAIDDDVLVAAKAMARQQDRSLGEVISELARRSLRRPRIGGERNGIPLLSPRPDSPPVTLEFVNELRDELS

Download         Length: 228 bp

>AT37134 NZ_AP023263:6010689-6010916 [Mesorhizobium sp. L-8-10]
ATGCGAACGACACTGGCGATTGACGATGATGTTCTGGTCGCGGCCAAGGCGATGGCCCGGCAGCAGGACCGAAGCCTCGG
AGAGGTGATCTCCGAGTTGGCGCGGCGTTCCTTGCGCAGGCCGAGGATCGGCGGCGAACGCAATGGCATTCCGCTGTTGT
CGCCCCGCCCCGACAGCCCCCCCGTTACGCTAGAGTTCGTCAATGAATTGCGCGACGAACTTTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References