Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vagCD/VapC-VagC |
Location | 3826612..3827279 | Replicon | chromosome |
Accession | NZ_AP023263 | ||
Organism | Mesorhizobium sp. L-8-10 |
Toxin (Protein)
Gene name | vagD | Uniprot ID | - |
Locus tag | JN280_RS17760 | Protein ID | WP_202313961.1 |
Coordinates | 3826860..3827279 (+) | Length | 140 a.a. |
Antitoxin (Protein)
Gene name | vagC | Uniprot ID | - |
Locus tag | JN280_RS17755 | Protein ID | WP_202313959.1 |
Coordinates | 3826612..3826860 (+) | Length | 83 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JN280_RS17725 | 3822066..3822611 | + | 546 | WP_202313946.1 | nuclear transport factor 2 family protein | - |
JN280_RS17730 | 3822611..3823132 | + | 522 | WP_202313948.1 | flavin reductase family protein | - |
JN280_RS17735 | 3823157..3824764 | + | 1608 | WP_202313950.1 | SDR family oxidoreductase | - |
JN280_RS17740 | 3824761..3825060 | + | 300 | WP_202313952.1 | hypothetical protein | - |
JN280_RS17745 | 3825103..3826197 | + | 1095 | WP_202313954.1 | LLM class flavin-dependent oxidoreductase | - |
JN280_RS17750 | 3826259..3826576 | - | 318 | WP_202313956.1 | DUF3175 domain-containing protein | - |
JN280_RS17755 | 3826612..3826860 | + | 249 | WP_202313959.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
JN280_RS17760 | 3826860..3827279 | + | 420 | WP_202313961.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
JN280_RS17765 | 3827514..3828278 | + | 765 | WP_202313963.1 | metallophosphoesterase | - |
JN280_RS17770 | 3828384..3829403 | - | 1020 | WP_202314827.1 | acyltransferase | - |
JN280_RS17775 | 3829430..3830698 | - | 1269 | WP_202313964.1 | O-antigen ligase family protein | - |
JN280_RS17780 | 3830764..3832053 | - | 1290 | WP_202313965.1 | polysaccharide export protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 140 a.a. Molecular weight: 15217.49 Da Isoelectric Point: 7.8847
>T37133 WP_202313961.1 NZ_AP023263:3826860-3827279 [Mesorhizobium sp. L-8-10]
MPAIYMLDTNICSFIMRERPASVLARLQNAAESQHQIVISVITYYEMLLGTVGRNASPRHARLVDAFVTRLSTILPWDAA
SAERATGIKQDLAAKGTPIGGNDTMIAGHALAADCVLVTNNTREFSRVQGLRFEDWVKG
MPAIYMLDTNICSFIMRERPASVLARLQNAAESQHQIVISVITYYEMLLGTVGRNASPRHARLVDAFVTRLSTILPWDAA
SAERATGIKQDLAAKGTPIGGNDTMIAGHALAADCVLVTNNTREFSRVQGLRFEDWVKG
Download Length: 420 bp
>T37133 NZ_AP023263:3826860-3827279 [Mesorhizobium sp. L-8-10]
ATGCCGGCCATCTATATGCTCGACACCAATATTTGCTCATTCATCATGCGCGAACGTCCAGCCTCCGTTCTTGCACGTTT
GCAGAACGCGGCGGAAAGCCAGCACCAGATCGTCATCTCGGTCATCACTTATTACGAAATGCTGCTGGGCACGGTCGGCC
GCAATGCCTCGCCTCGTCATGCGCGGCTGGTGGATGCTTTCGTCACCCGTCTCTCCACCATCCTGCCATGGGATGCGGCG
TCCGCGGAACGCGCCACAGGCATCAAGCAGGATTTGGCGGCCAAGGGAACACCCATAGGCGGCAATGATACGATGATCGC
AGGTCATGCGCTGGCCGCTGATTGTGTGCTGGTGACGAACAACACCCGCGAATTCTCACGTGTGCAGGGGCTGCGGTTTG
AGGATTGGGTGAAGGGGTAA
ATGCCGGCCATCTATATGCTCGACACCAATATTTGCTCATTCATCATGCGCGAACGTCCAGCCTCCGTTCTTGCACGTTT
GCAGAACGCGGCGGAAAGCCAGCACCAGATCGTCATCTCGGTCATCACTTATTACGAAATGCTGCTGGGCACGGTCGGCC
GCAATGCCTCGCCTCGTCATGCGCGGCTGGTGGATGCTTTCGTCACCCGTCTCTCCACCATCCTGCCATGGGATGCGGCG
TCCGCGGAACGCGCCACAGGCATCAAGCAGGATTTGGCGGCCAAGGGAACACCCATAGGCGGCAATGATACGATGATCGC
AGGTCATGCGCTGGCCGCTGATTGTGTGCTGGTGACGAACAACACCCGCGAATTCTCACGTGTGCAGGGGCTGCGGTTTG
AGGATTGGGTGAAGGGGTAA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9663.87 Da Isoelectric Point: 4.5257
>AT37133 WP_202313959.1 NZ_AP023263:3826612-3826860 [Mesorhizobium sp. L-8-10]
MTRTVSIFRNNRNQAIRLPKDFEFQGVTELTIERQGDTILLRPVRPDWLSFMKEPLSDADFLDERPELIEEGRFSLDDDG
KH
MTRTVSIFRNNRNQAIRLPKDFEFQGVTELTIERQGDTILLRPVRPDWLSFMKEPLSDADFLDERPELIEEGRFSLDDDG
KH
Download Length: 249 bp
>AT37133 NZ_AP023263:3826612-3826860 [Mesorhizobium sp. L-8-10]
ATGACCCGCACCGTGTCCATCTTTCGCAACAACCGCAACCAAGCGATCCGTCTGCCCAAAGATTTTGAGTTCCAGGGGGT
GACCGAATTGACCATTGAGCGGCAGGGCGACACGATACTGCTGCGTCCCGTCCGGCCGGACTGGCTATCGTTCATGAAAG
AACCGCTTAGCGATGCGGATTTCCTCGACGAACGGCCCGAGCTGATCGAAGAGGGACGGTTCTCTCTTGATGATGACGGG
AAGCATTGA
ATGACCCGCACCGTGTCCATCTTTCGCAACAACCGCAACCAAGCGATCCGTCTGCCCAAAGATTTTGAGTTCCAGGGGGT
GACCGAATTGACCATTGAGCGGCAGGGCGACACGATACTGCTGCGTCCCGTCCGGCCGGACTGGCTATCGTTCATGAAAG
AACCGCTTAGCGATGCGGATTTCCTCGACGAACGGCCCGAGCTGATCGAAGAGGGACGGTTCTCTCTTGATGATGACGGG
AAGCATTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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