Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3504033..3504811 Replicon chromosome
Accession NZ_AP023263
Organism Mesorhizobium sp. L-8-10

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag JN280_RS16230 Protein ID WP_202313535.1
Coordinates 3504320..3504811 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag JN280_RS16225 Protein ID WP_202313534.1
Coordinates 3504033..3504323 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN280_RS16210 3499321..3500613 + 1293 WP_202313531.1 hypothetical protein -
JN280_RS16215 3500692..3501867 + 1176 WP_202313532.1 DUF2333 family protein -
JN280_RS16220 3502100..3503779 + 1680 WP_202313533.1 formate--tetrahydrofolate ligase -
JN280_RS16225 3504033..3504323 + 291 WP_202313534.1 DUF1778 domain-containing protein Antitoxin
JN280_RS16230 3504320..3504811 + 492 WP_202313535.1 GNAT family N-acetyltransferase Toxin
JN280_RS16235 3504940..3505473 - 534 WP_202314803.1 nucleoside-diphosphate kinase -
JN280_RS16240 3505615..3506028 - 414 WP_202313536.1 nucleoside diphosphate kinase regulator -
JN280_RS16245 3506311..3507084 - 774 WP_202313538.1 amino acid ABC transporter ATP-binding protein -
JN280_RS16250 3507081..3507761 - 681 WP_202313540.1 ABC transporter permease subunit -
JN280_RS16255 3507936..3508709 - 774 WP_202313542.1 amino acid ABC transporter substrate-binding protein -
JN280_RS16260 3508941..3509654 - 714 WP_202313544.1 DUF1868 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(40-143)

Antitoxin

Vibrio phage ICP1, Orf50

(5-90)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17957.68 Da        Isoelectric Point: 7.4748

>T37132 WP_202313535.1 NZ_AP023263:3504320-3504811 [Mesorhizobium sp. L-8-10]
VTEFRIEKLHRRHAVDAFDCGEELLNRFLVRFALPNQQANASQTYVGLADDAVIGFHTLVVGEVGYGDAPDRLTMGLARH
PVPVMLLARLGVSVGWQGRSIGAGLLRDAVLRTLQAADIVGIRAIAVHAKNEQARSFYQRFDFVESPTDPLHLFALIKDL
KGL

Download         Length: 492 bp

>T37132 NZ_AP023263:3504320-3504811 [Mesorhizobium sp. L-8-10]
GTGACGGAGTTCCGCATTGAAAAACTCCATCGTCGCCATGCCGTCGATGCGTTTGATTGCGGCGAGGAACTGCTGAACCG
GTTCCTTGTCCGTTTCGCGCTGCCCAATCAGCAGGCCAACGCTTCGCAAACCTATGTGGGGTTGGCCGATGACGCCGTCA
TAGGCTTTCATACCCTGGTCGTTGGCGAGGTCGGCTACGGTGACGCGCCGGATCGTCTGACCATGGGCCTTGCGCGCCAT
CCGGTGCCCGTGATGCTTTTGGCCCGCCTTGGCGTCAGCGTCGGTTGGCAGGGCAGGAGTATCGGCGCGGGTCTGCTGCG
CGACGCCGTTCTACGCACGTTGCAAGCCGCGGACATCGTCGGCATCAGGGCTATCGCGGTTCATGCCAAGAACGAACAGG
CGCGCTCCTTCTATCAGCGGTTCGATTTCGTGGAATCGCCCACTGATCCGTTGCATCTGTTCGCGCTCATCAAGGATTTG
AAAGGCTTGTAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10739.28 Da        Isoelectric Point: 8.9128

>AT37132 WP_202313534.1 NZ_AP023263:3504033-3504323 [Mesorhizobium sp. L-8-10]
MAPRTTRTEKLDIRLTPEAKRVLAAAAQAERRSLTDFVLKSALGRAEEALADRRVFLLNPEQWETFIAALDAPPRDMPHL
RNLLNEPSIFSGNSPS

Download         Length: 291 bp

>AT37132 NZ_AP023263:3504033-3504323 [Mesorhizobium sp. L-8-10]
ATGGCTCCACGCACGACCCGCACCGAAAAACTCGATATCCGCCTGACCCCCGAGGCGAAACGTGTGCTGGCCGCCGCCGC
GCAGGCCGAGCGCCGTTCACTGACTGACTTCGTGCTCAAAAGCGCTCTCGGCCGTGCCGAGGAGGCGCTGGCCGACCGCC
GTGTGTTCTTGCTCAACCCCGAACAGTGGGAAACTTTCATCGCAGCCCTCGATGCGCCGCCGCGCGACATGCCGCACCTG
CGCAATCTGCTGAACGAGCCGAGCATCTTCTCCGGCAACAGCCCTTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References