Detailed information of TA system TA037132

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 3504033..3504811
• Replicon: chromosome
• Accession: NZ_AP023263
• Organism: Mesorhizobium sp. L-8-10

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: -
• Locus tag: JN280_RS16230
• Protein ID: WP_202313535.1
• Coordinates: 3504320..3504811 (+)
• Length: 164 a.a.

Antitoxin (Protein)

• Gene name: tacA
• Uniprot ID: -
• Locus tag: JN280_RS16225
• Protein ID: WP_202313534.1
• Coordinates: 3504033..3504323 (+)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JN280_RS16210	3499321..3500613	+	1293	WP_202313531.1	hypothetical protein	-
JN280_RS16215	3500692..3501867	+	1176	WP_202313532.1	DUF2333 family protein	-
JN280_RS16220	3502100..3503779	+	1680	WP_202313533.1	formate--tetrahydrofolate ligase	-
JN280_RS16225	3504033..3504323	+	291	WP_202313534.1	DUF1778 domain-containing protein	Antitoxin
JN280_RS16230	3504320..3504811	+	492	WP_202313535.1	GNAT family N-acetyltransferase	Toxin
JN280_RS16235	3504940..3505473	-	534	WP_202314803.1	nucleoside-diphosphate kinase	-
JN280_RS16240	3505615..3506028	-	414	WP_202313536.1	nucleoside diphosphate kinase regulator	-
JN280_RS16245	3506311..3507084	-	774	WP_202313538.1	amino acid ABC transporter ATP-binding protein	-
JN280_RS16250	3507081..3507761	-	681	WP_202313540.1	ABC transporter permease subunit	-
JN280_RS16255	3507936..3508709	-	774	WP_202313542.1	amino acid ABC transporter substrate-binding protein	-
JN280_RS16260	3508941..3509654	-	714	WP_202313544.1	DUF1868 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (40-143)

Antitoxin

• Vibrio phage ICP1, Orf50 (5-90)

Sequences

Toxin

Protein

• Length: 164 a.a.
• Molecular weight: 17957.68 Da
• Isoelectric Point: 7.4748

>T37132 WP_202313535.1 NZ_AP023263:3504320-3504811 [Mesorhizobium sp. L-8-10]
VTEFRIEKLHRRHAVDAFDCGEELLNRFLVRFALPNQQANASQTYVGLADDAVIGFHTLVVGEVGYGDAPDRLTMGLARH
PVPVMLLARLGVSVGWQGRSIGAGLLRDAVLRTLQAADIVGIRAIAVHAKNEQARSFYQRFDFVESPTDPLHLFALIKDL
KGL

Nucleotide

• Length: 492 bp

>T37132 NZ_AP023263:3504320-3504811 [Mesorhizobium sp. L-8-10]
GTGACGGAGTTCCGCATTGAAAAACTCCATCGTCGCCATGCCGTCGATGCGTTTGATTGCGGCGAGGAACTGCTGAACCG
GTTCCTTGTCCGTTTCGCGCTGCCCAATCAGCAGGCCAACGCTTCGCAAACCTATGTGGGGTTGGCCGATGACGCCGTCA
TAGGCTTTCATACCCTGGTCGTTGGCGAGGTCGGCTACGGTGACGCGCCGGATCGTCTGACCATGGGCCTTGCGCGCCAT
CCGGTGCCCGTGATGCTTTTGGCCCGCCTTGGCGTCAGCGTCGGTTGGCAGGGCAGGAGTATCGGCGCGGGTCTGCTGCG
CGACGCCGTTCTACGCACGTTGCAAGCCGCGGACATCGTCGGCATCAGGGCTATCGCGGTTCATGCCAAGAACGAACAGG
CGCGCTCCTTCTATCAGCGGTTCGATTTCGTGGAATCGCCCACTGATCCGTTGCATCTGTTCGCGCTCATCAAGGATTTG
AAAGGCTTGTAG

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10739.28 Da
• Isoelectric Point: 8.9128

>AT37132 WP_202313534.1 NZ_AP023263:3504033-3504323 [Mesorhizobium sp. L-8-10]
MAPRTTRTEKLDIRLTPEAKRVLAAAAQAERRSLTDFVLKSALGRAEEALADRRVFLLNPEQWETFIAALDAPPRDMPHL
RNLLNEPSIFSGNSPS

Nucleotide

• Length: 291 bp

>AT37132 NZ_AP023263:3504033-3504323 [Mesorhizobium sp. L-8-10]
ATGGCTCCACGCACGACCCGCACCGAAAAACTCGATATCCGCCTGACCCCCGAGGCGAAACGTGTGCTGGCCGCCGCCGC
GCAGGCCGAGCGCCGTTCACTGACTGACTTCGTGCTCAAAAGCGCTCTCGGCCGTGCCGAGGAGGCGCTGGCCGACCGCC
GTGTGTTCTTGCTCAACCCCGAACAGTGGGAAACTTTCATCGCAGCCCTCGATGCGCCGCCGCGCGACATGCCGCACCTG
CGCAATCTGCTGAACGAGCCGAGCATCTTCTCCGGCAACAGCCCTTCGTGA