Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3077677..3078317 Replicon chromosome
Accession NZ_AP023263
Organism Mesorhizobium sp. L-8-10

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JN280_RS14275 Protein ID WP_202313019.1
Coordinates 3077677..3078063 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JN280_RS14280 Protein ID WP_202313020.1
Coordinates 3078063..3078317 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN280_RS14265 3073906..3074838 - 933 WP_202313017.1 helix-turn-helix domain-containing protein -
JN280_RS14270 3075069..3077171 + 2103 WP_202313018.1 PQQ-dependent dehydrogenase, methanol/ethanol family -
JN280_RS14275 3077677..3078063 - 387 WP_202313019.1 type II toxin-antitoxin system VapC family toxin Toxin
JN280_RS14280 3078063..3078317 - 255 WP_202313020.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
JN280_RS14285 3078664..3080226 - 1563 WP_202313021.1 sulfatase -
JN280_RS14290 3080286..3081272 - 987 WP_202313022.1 aliphatic sulfonate ABC transporter substrate-binding protein -
JN280_RS14295 3081292..3082074 - 783 WP_202314764.1 ABC transporter ATP-binding protein -
JN280_RS14300 3082092..3082844 - 753 WP_202314765.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 13872.63 Da        Isoelectric Point: 4.5833

>T37131 WP_202313019.1 NZ_AP023263:c3078063-3077677 [Mesorhizobium sp. L-8-10]
MVIDTSAIVAIALNEPEAPSFEQRIADDPVRLISAATVLEAAMVIEARFGDPGGGEFDLWLHKADVEIVAVKAEHADQAR
RAWRRYGKGRHPAGLNYGDCFSYALAALTGEPLLYKGNDFSQTDIQAA

Download         Length: 387 bp

>T37131 NZ_AP023263:c3078063-3077677 [Mesorhizobium sp. L-8-10]
ATGGTCATCGATACCTCGGCCATCGTCGCCATAGCGCTCAATGAGCCGGAAGCACCTTCCTTCGAGCAGCGCATTGCCGA
CGACCCGGTGCGCCTCATCTCTGCCGCAACCGTGCTGGAAGCGGCCATGGTGATCGAGGCCCGCTTCGGCGACCCTGGCG
GCGGCGAGTTCGACCTGTGGCTGCACAAGGCCGATGTCGAGATCGTCGCGGTCAAAGCCGAGCATGCCGACCAGGCCCGC
CGCGCCTGGAGGCGCTACGGCAAGGGCCGCCACCCAGCCGGGCTGAACTACGGCGACTGCTTCTCCTATGCACTGGCCGC
CCTGACCGGCGAGCCCCTACTCTACAAGGGCAACGACTTTTCGCAGACCGATATCCAAGCGGCGTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9395.62 Da        Isoelectric Point: 9.9858

>AT37131 WP_202313020.1 NZ_AP023263:c3078317-3078063 [Mesorhizobium sp. L-8-10]
MALSIKDPETERLARKLATKTGESITIATRRALEERLRRVSSDARKTALLEDLAASRRRWSSLPVLDNRSADEIVGYDEN
GLPS

Download         Length: 255 bp

>AT37131 NZ_AP023263:c3078317-3078063 [Mesorhizobium sp. L-8-10]
ATGGCGCTGAGCATCAAAGATCCGGAAACCGAGCGGCTCGCCCGCAAGCTCGCCACGAAAACCGGCGAGAGCATCACCAT
TGCCACACGGCGGGCGCTGGAGGAGCGGCTGCGCCGCGTCAGCTCCGACGCCCGCAAGACCGCACTTCTGGAGGATCTTG
CCGCCAGCCGCCGGCGCTGGAGTTCCCTGCCCGTCCTCGACAATCGCAGCGCCGATGAAATCGTCGGCTACGACGAGAAT
GGGCTGCCGAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References