Detailed information of TA system TA037130

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yoeB-relE/YoeB-RelB
• Location: 2997957..2998462
• Replicon: chromosome
• Accession: NZ_AP023263
• Organism: Mesorhizobium sp. L-8-10

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: JN280_RS13935
• Protein ID: WP_202312937.1
• Coordinates: 2998208..2998462 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: JN280_RS13930
• Protein ID: WP_202312935.1
• Coordinates: 2997957..2998211 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JN280_RS13925	2996356..2997810	+	1455	WP_202312933.1	glutamate synthase subunit beta	-
JN280_RS13930	2997957..2998211	+	255	WP_202312935.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
JN280_RS13935	2998208..2998462	+	255	WP_202312937.1	Txe/YoeB family addiction module toxin	Toxin
JN280_RS13940	2998635..2999816	-	1182	WP_202314754.1	DUF459 domain-containing protein	-
JN280_RS13945	3000017..3001240	-	1224	WP_202312939.1	lytic murein transglycosylase	-
JN280_RS13950	3001607..3002491	+	885	WP_202312941.1	UTP--glucose-1-phosphate uridylyltransferase GalU	-
JN280_RS13955	3002575..3003336	-	762	WP_202312942.1	universal stress protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10038.56 Da
• Isoelectric Point: 9.7081

>T37130 WP_202312937.1 NZ_AP023263:2998208-2998462 [Mesorhizobium sp. L-8-10]
VKLIFSERAWEDCLHWQTHDRKLLLRINDLIKECSRTPFAGSGKPEPLRGALSGWWSRRISREQRLVYRPTEEGLLIAQC
RYHY

Nucleotide

• Length: 255 bp

>T37130 NZ_AP023263:2998208-2998462 [Mesorhizobium sp. L-8-10]
GTGAAACTCATCTTCAGCGAGCGCGCCTGGGAGGACTGCCTCCATTGGCAGACCCATGACCGCAAGCTGCTCCTGCGCAT
AAACGATCTCATCAAAGAGTGCAGCCGGACGCCGTTCGCCGGCAGCGGCAAGCCGGAACCGTTGCGCGGCGCCCTATCCG
GCTGGTGGTCGCGGCGGATCTCTCGGGAGCAGCGGCTGGTGTACCGACCCACCGAGGAGGGGCTGCTGATCGCGCAGTGC
CGGTATCATTATTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9531.78 Da
• Isoelectric Point: 5.8768

>AT37130 WP_202312935.1 NZ_AP023263:2997957-2998211 [Mesorhizobium sp. L-8-10]
MRTTSYSDLRKNLAAMIDRVNADHEPVIITRDRGKPTAVLMSMEDFASYEETRYLLKSPRNAERLAESIAELDAGKGTKR
ELSE

Nucleotide

• Length: 255 bp

>AT37130 NZ_AP023263:2997957-2998211 [Mesorhizobium sp. L-8-10]
ATGCGTACAACCTCCTACAGCGACCTTCGCAAGAATCTCGCGGCCATGATCGACCGGGTCAATGCCGATCATGAGCCTGT
CATAATCACGCGCGACCGCGGCAAGCCTACGGCGGTGTTGATGTCGATGGAGGACTTCGCCTCCTATGAGGAAACTCGGT
ATCTGCTGAAGAGTCCCCGCAACGCGGAGCGACTTGCCGAATCGATCGCAGAGCTTGACGCGGGCAAGGGAACGAAGCGT
GAGCTTTCGGAGTGA