Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-VagC |
Location | 2760582..2761249 | Replicon | chromosome |
Accession | NZ_AP023263 | ||
Organism | Mesorhizobium sp. L-8-10 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | JN280_RS12885 | Protein ID | WP_202312673.1 |
Coordinates | 2760582..2760989 (-) | Length | 136 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | JN280_RS12890 | Protein ID | WP_202312674.1 |
Coordinates | 2760986..2761249 (-) | Length | 88 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JN280_RS12865 | 2756848..2757636 | - | 789 | WP_202314732.1 | helix-turn-helix domain-containing protein | - |
JN280_RS12870 | 2757726..2758583 | + | 858 | WP_202312669.1 | CoA transferase subunit A | - |
JN280_RS12875 | 2758580..2759377 | + | 798 | WP_202312671.1 | CoA-transferase subunit beta | - |
JN280_RS12880 | 2759380..2760585 | + | 1206 | WP_202312672.1 | 3-oxoadipyl-CoA thiolase | - |
JN280_RS12885 | 2760582..2760989 | - | 408 | WP_202312673.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
JN280_RS12890 | 2760986..2761249 | - | 264 | WP_202312674.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
JN280_RS12895 | 2761316..2762296 | - | 981 | WP_202312675.1 | GlxA family transcriptional regulator | - |
JN280_RS12900 | 2762441..2763346 | + | 906 | WP_202312676.1 | 3-keto-5-aminohexanoate cleavage protein | - |
JN280_RS12905 | 2763351..2764463 | + | 1113 | WP_202312677.1 | carnitine 3-dehydrogenase | - |
JN280_RS12910 | 2764468..2765631 | + | 1164 | WP_202312678.1 | acyl-CoA dehydrogenase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 136 a.a. Molecular weight: 14846.07 Da Isoelectric Point: 6.8715
>T37129 WP_202312673.1 NZ_AP023263:c2760989-2760582 [Mesorhizobium sp. L-8-10]
MNTRYMLDTNAIGLIVTKRSGPVADRHSKIPPQDICVSAISFGEIQFGLAKRPEATRLAGVTADFFAEVDVLQWSAQEAR
LYGHLRAHMERQAKSLGALDMLIAAHALSVGATLVTSDRAFRLVPDLRIEDWLEG
MNTRYMLDTNAIGLIVTKRSGPVADRHSKIPPQDICVSAISFGEIQFGLAKRPEATRLAGVTADFFAEVDVLQWSAQEAR
LYGHLRAHMERQAKSLGALDMLIAAHALSVGATLVTSDRAFRLVPDLRIEDWLEG
Download Length: 408 bp
>T37129 NZ_AP023263:c2760989-2760582 [Mesorhizobium sp. L-8-10]
ATGAATACGCGCTACATGCTCGATACGAACGCTATCGGACTGATCGTGACGAAGCGATCGGGACCTGTCGCCGACCGACA
CAGCAAAATCCCGCCCCAGGATATTTGCGTGTCCGCCATCTCTTTCGGGGAAATCCAGTTTGGGTTGGCAAAGCGCCCGG
AGGCTACCCGTTTGGCGGGGGTAACAGCCGACTTCTTCGCCGAGGTCGACGTGCTGCAATGGTCGGCACAAGAAGCAAGG
CTCTATGGCCACCTCCGCGCCCATATGGAGCGACAGGCGAAAAGCCTAGGCGCACTCGACATGCTCATCGCCGCCCATGC
GCTTTCTGTCGGCGCGACGCTCGTCACGAGCGATCGCGCCTTCCGTCTCGTCCCCGACCTCCGGATCGAGGACTGGCTGG
AGGGTTAG
ATGAATACGCGCTACATGCTCGATACGAACGCTATCGGACTGATCGTGACGAAGCGATCGGGACCTGTCGCCGACCGACA
CAGCAAAATCCCGCCCCAGGATATTTGCGTGTCCGCCATCTCTTTCGGGGAAATCCAGTTTGGGTTGGCAAAGCGCCCGG
AGGCTACCCGTTTGGCGGGGGTAACAGCCGACTTCTTCGCCGAGGTCGACGTGCTGCAATGGTCGGCACAAGAAGCAAGG
CTCTATGGCCACCTCCGCGCCCATATGGAGCGACAGGCGAAAAGCCTAGGCGCACTCGACATGCTCATCGCCGCCCATGC
GCTTTCTGTCGGCGCGACGCTCGTCACGAGCGATCGCGCCTTCCGTCTCGTCCCCGACCTCCGGATCGAGGACTGGCTGG
AGGGTTAG
Antitoxin
Download Length: 88 a.a. Molecular weight: 10064.31 Da Isoelectric Point: 5.1751
>AT37129 WP_202312674.1 NZ_AP023263:c2761249-2760986 [Mesorhizobium sp. L-8-10]
MTAVAKLFMNGRSQAVRLPQEFRFKGTEVEIWRDPATGHVILAEKPQRTGSWEKFFAARDALRPEDIPEDFLKDRDQGTQ
ERDDPFA
MTAVAKLFMNGRSQAVRLPQEFRFKGTEVEIWRDPATGHVILAEKPQRTGSWEKFFAARDALRPEDIPEDFLKDRDQGTQ
ERDDPFA
Download Length: 264 bp
>AT37129 NZ_AP023263:c2761249-2760986 [Mesorhizobium sp. L-8-10]
ATGACAGCCGTCGCAAAGCTCTTCATGAACGGGCGCAGCCAGGCCGTGCGCCTTCCCCAGGAGTTTCGGTTCAAGGGAAC
GGAAGTGGAGATCTGGCGGGACCCGGCAACGGGACACGTGATCCTGGCAGAGAAACCGCAGCGGACAGGGTCGTGGGAGA
AGTTCTTTGCCGCGCGGGACGCGCTCAGGCCGGAGGACATTCCCGAAGATTTCCTGAAGGACCGGGACCAGGGGACTCAG
GAGCGGGACGACCCCTTCGCATGA
ATGACAGCCGTCGCAAAGCTCTTCATGAACGGGCGCAGCCAGGCCGTGCGCCTTCCCCAGGAGTTTCGGTTCAAGGGAAC
GGAAGTGGAGATCTGGCGGGACCCGGCAACGGGACACGTGATCCTGGCAGAGAAACCGCAGCGGACAGGGTCGTGGGAGA
AGTTCTTTGCCGCGCGGGACGCGCTCAGGCCGGAGGACATTCCCGAAGATTTCCTGAAGGACCGGGACCAGGGGACTCAG
GAGCGGGACGACCCCTTCGCATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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