Detailed information of TA system TA037126

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 915356..916367
• Replicon: chromosome
• Accession: NZ_AP023263
• Organism: Mesorhizobium sp. L-8-10

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: JN280_RS04150
• Protein ID: WP_202314517.1
• Coordinates: 915356..915925 (-)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: JN280_RS04155
• Protein ID: WP_202310248.1
• Coordinates: 915927..916367 (-)
• Length: 147 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JN280_RS04125	910470..911216	-	747	WP_202310243.1	GntR family transcriptional regulator	-
JN280_RS04130	911213..912088	-	876	WP_202310244.1	ROK family protein	-
JN280_RS04135	912085..912933	-	849	WP_202310245.1	carbohydrate ABC transporter permease	-
JN280_RS04140	912930..913826	-	897	WP_202310246.1	sugar ABC transporter permease	-
JN280_RS04145	913890..915185	-	1296	WP_202310247.1	extracellular solute-binding protein	-
JN280_RS04150	915356..915925	-	570	WP_202314517.1	PIN domain-containing protein	Toxin
JN280_RS04155	915927..916367	-	441	WP_202310248.1	helix-turn-helix domain-containing protein	Antitoxin
JN280_RS04160	916642..917565	-	924	WP_202314519.1	alpha/beta hydrolase	-
JN280_RS04165	917742..921359	-	3618	WP_202310249.1	hydantoinase B/oxoprolinase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (6-113)

Antitoxin

• Helix-turn-helix domain, group 17 (76-124)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21219.47 Da
• Isoelectric Point: 4.8050

>T37126 WP_202314517.1 NZ_AP023263:c915925-915356 [Mesorhizobium sp. L-8-10]
IAGYTVVLDACVLYPAPLRDFLLELAGSGMFRARWSDIIHDEWIRNLLKARPDLSRDRLMRTRRLMDDSVLGSLVEGFEE
LIPVLELPDPDDRHVLAAAIHSGSDAIVTVNLKDFPAEVAKRYELEILHPDDFLYQQFGLDPAAVVLAARNCRARLKSPP
RSGGEYLATLEAQGLPLLVSELRKFEDLL

Nucleotide

• Length: 570 bp

>T37126 NZ_AP023263:c915925-915356 [Mesorhizobium sp. L-8-10]
ATCGCCGGCTACACGGTCGTTCTCGACGCGTGCGTGCTGTATCCTGCACCGCTGCGCGATTTCCTGCTAGAACTTGCCGG
AAGCGGCATGTTTCGAGCACGTTGGTCCGATATCATCCACGACGAATGGATCCGCAACCTGTTGAAGGCTCGTCCCGATC
TCAGCCGCGATCGTCTCATGCGTACGCGTCGGCTGATGGACGACAGTGTGCTCGGGAGCCTGGTCGAGGGGTTCGAAGAG
CTGATCCCCGTGTTGGAGTTGCCCGATCCTGACGATCGGCATGTGCTTGCCGCGGCGATACACAGTGGAAGCGACGCGAT
CGTCACCGTCAACCTCAAGGATTTTCCTGCCGAGGTTGCAAAACGCTACGAGCTGGAAATTCTTCACCCTGACGATTTTC
TCTATCAGCAGTTCGGGCTTGATCCGGCGGCAGTTGTCCTTGCTGCCCGAAATTGCCGTGCGCGGTTGAAAAGCCCGCCG
AGAAGCGGCGGCGAGTACCTCGCTACGCTCGAGGCGCAGGGCCTGCCTTTGCTCGTCAGCGAACTGCGCAAGTTCGAAGA
CCTGCTCTGA

Antitoxin

Protein

• Length: 147 a.a.
• Molecular weight: 16229.58 Da
• Isoelectric Point: 7.5242

>AT37126 WP_202310248.1 NZ_AP023263:c916367-915927 [Mesorhizobium sp. L-8-10]
MLLEHPDTIVPTADDAELAAKASRILSRRGKNGLRIRLDDGEELTLPVAAARLLTHLLTEMSQGNAVTLIPVHAELTTRQ
AAEYLNVSRPHVVKLLEQSRIPYHKVGTHRRIRFSDLEAFKRQQETARGQALDALAAEAQEMGMGY

Nucleotide

• Length: 441 bp

>AT37126 NZ_AP023263:c916367-915927 [Mesorhizobium sp. L-8-10]
ATGTTGCTCGAACACCCCGATACGATCGTGCCCACGGCCGACGATGCGGAATTGGCGGCTAAGGCGAGCCGGATCCTGTC
GCGTCGCGGCAAGAACGGCCTGCGCATCCGCCTCGACGATGGTGAGGAACTTACCCTTCCCGTCGCGGCGGCAAGATTGC
TTACGCATCTGCTCACCGAAATGTCACAGGGAAACGCGGTTACTCTGATCCCGGTGCATGCGGAGCTCACGACACGCCAG
GCGGCTGAATATCTCAACGTTTCGCGGCCCCATGTGGTCAAGCTGCTGGAGCAATCCAGGATTCCCTACCACAAGGTTGG
AACGCACAGGCGCATAAGGTTCAGCGATCTTGAAGCCTTCAAGCGGCAGCAGGAAACCGCGCGAGGTCAGGCTCTCGATG
CCTTGGCCGCCGAAGCCCAGGAAATGGGGATGGGCTATTAG