Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE-RelB |
Location | 545663..546267 | Replicon | chromosome |
Accession | NZ_AP023263 | ||
Organism | Mesorhizobium sp. L-8-10 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | JN280_RS02500 | Protein ID | WP_202309957.1 |
Coordinates | 545962..546267 (+) | Length | 102 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | JN280_RS02495 | Protein ID | WP_202314476.1 |
Coordinates | 545663..545965 (+) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JN280_RS02470 | 540778..541839 | - | 1062 | WP_202309952.1 | agmatinase | - |
JN280_RS02475 | 541955..542929 | + | 975 | WP_202309953.1 | transcriptional regulator GcvA | - |
JN280_RS02480 | 543101..544261 | + | 1161 | WP_202309954.1 | iron-containing alcohol dehydrogenase | - |
JN280_RS02485 | 544261..544692 | + | 432 | WP_202309955.1 | acyl-CoA thioesterase | - |
JN280_RS02490 | 544797..545570 | + | 774 | WP_202309956.1 | SH3 domain-containing protein | - |
JN280_RS02495 | 545663..545965 | + | 303 | WP_202314476.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
JN280_RS02500 | 545962..546267 | + | 306 | WP_202309957.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
JN280_RS02505 | 546391..547695 | + | 1305 | WP_202309958.1 | nicotinate phosphoribosyltransferase | - |
JN280_RS02510 | 547751..549136 | + | 1386 | WP_202314477.1 | hypothetical protein | - |
JN280_RS02515 | 549287..550594 | + | 1308 | WP_202309959.1 | ABC transporter substrate-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 102 a.a. Molecular weight: 11463.14 Da Isoelectric Point: 8.6584
>T37124 WP_202309957.1 NZ_AP023263:545962-546267 [Mesorhizobium sp. L-8-10]
VKLVWAQFAVTDRVRIFGHIEADNPRAAVRVDEQIARAVRRLLDFPESGRPGRVAGTREMVVPRTPYIAAYVVTSDRIRI
LRVLHGAQIWPDEIADDTDFP
VKLVWAQFAVTDRVRIFGHIEADNPRAAVRVDEQIARAVRRLLDFPESGRPGRVAGTREMVVPRTPYIAAYVVTSDRIRI
LRVLHGAQIWPDEIADDTDFP
Download Length: 306 bp
>T37124 NZ_AP023263:545962-546267 [Mesorhizobium sp. L-8-10]
GTGAAGCTTGTCTGGGCACAATTTGCCGTTACGGATCGCGTCAGAATCTTCGGCCACATCGAAGCCGACAATCCGAGGGC
AGCGGTTCGAGTAGACGAGCAAATCGCTCGTGCGGTGAGGCGCCTGCTCGATTTTCCCGAAAGCGGACGTCCCGGCCGGG
TCGCAGGAACACGCGAGATGGTTGTACCTCGCACGCCCTACATCGCTGCCTATGTCGTGACGTCCGACAGGATTCGCATC
TTGCGTGTCCTCCACGGAGCACAGATCTGGCCGGACGAGATTGCCGACGACACCGATTTTCCGTGA
GTGAAGCTTGTCTGGGCACAATTTGCCGTTACGGATCGCGTCAGAATCTTCGGCCACATCGAAGCCGACAATCCGAGGGC
AGCGGTTCGAGTAGACGAGCAAATCGCTCGTGCGGTGAGGCGCCTGCTCGATTTTCCCGAAAGCGGACGTCCCGGCCGGG
TCGCAGGAACACGCGAGATGGTTGTACCTCGCACGCCCTACATCGCTGCCTATGTCGTGACGTCCGACAGGATTCGCATC
TTGCGTGTCCTCCACGGAGCACAGATCTGGCCGGACGAGATTGCCGACGACACCGATTTTCCGTGA
Antitoxin
Download Length: 101 a.a. Molecular weight: 10917.33 Da Isoelectric Point: 4.5141
>AT37124 WP_202314476.1 NZ_AP023263:545663-545965 [Mesorhizobium sp. L-8-10]
MVSNALIQTRIDADIKDRATAVLENMGLTVSDAVRILLTRTANEGALPLELVTNSEAHDAWFRAKVLQALEDARPDVDDD
EAETQFVARRLAALGKTGKQ
MVSNALIQTRIDADIKDRATAVLENMGLTVSDAVRILLTRTANEGALPLELVTNSEAHDAWFRAKVLQALEDARPDVDDD
EAETQFVARRLAALGKTGKQ
Download Length: 303 bp
>AT37124 NZ_AP023263:545663-545965 [Mesorhizobium sp. L-8-10]
ATGGTTTCAAACGCACTGATCCAGACACGCATCGACGCCGATATAAAGGACCGCGCGACGGCTGTGCTCGAGAACATGGG
CCTCACGGTCTCCGATGCGGTCCGCATTCTGCTGACACGTACCGCGAACGAAGGCGCCTTGCCGCTCGAACTCGTCACCA
ACAGCGAGGCCCATGATGCCTGGTTCCGCGCAAAGGTCCTGCAGGCGCTTGAGGATGCGCGGCCGGACGTGGACGACGAC
GAAGCGGAGACGCAGTTTGTGGCCCGACGGCTGGCCGCTTTGGGCAAGACCGGCAAACAGTGA
ATGGTTTCAAACGCACTGATCCAGACACGCATCGACGCCGATATAAAGGACCGCGCGACGGCTGTGCTCGAGAACATGGG
CCTCACGGTCTCCGATGCGGTCCGCATTCTGCTGACACGTACCGCGAACGAAGGCGCCTTGCCGCTCGAACTCGTCACCA
ACAGCGAGGCCCATGATGCCTGGTTCCGCGCAAAGGTCCTGCAGGCGCTTGAGGATGCGCGGCCGGACGTGGACGACGAC
GAAGCGGAGACGCAGTTTGTGGCCCGACGGCTGGCCGCTTTGGGCAAGACCGGCAAACAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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