Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 545663..546267 Replicon chromosome
Accession NZ_AP023263
Organism Mesorhizobium sp. L-8-10

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JN280_RS02500 Protein ID WP_202309957.1
Coordinates 545962..546267 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JN280_RS02495 Protein ID WP_202314476.1
Coordinates 545663..545965 (+) Length 101 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN280_RS02470 540778..541839 - 1062 WP_202309952.1 agmatinase -
JN280_RS02475 541955..542929 + 975 WP_202309953.1 transcriptional regulator GcvA -
JN280_RS02480 543101..544261 + 1161 WP_202309954.1 iron-containing alcohol dehydrogenase -
JN280_RS02485 544261..544692 + 432 WP_202309955.1 acyl-CoA thioesterase -
JN280_RS02490 544797..545570 + 774 WP_202309956.1 SH3 domain-containing protein -
JN280_RS02495 545663..545965 + 303 WP_202314476.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
JN280_RS02500 545962..546267 + 306 WP_202309957.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JN280_RS02505 546391..547695 + 1305 WP_202309958.1 nicotinate phosphoribosyltransferase -
JN280_RS02510 547751..549136 + 1386 WP_202314477.1 hypothetical protein -
JN280_RS02515 549287..550594 + 1308 WP_202309959.1 ABC transporter substrate-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 102 a.a.        Molecular weight: 11463.14 Da        Isoelectric Point: 8.6584

>T37124 WP_202309957.1 NZ_AP023263:545962-546267 [Mesorhizobium sp. L-8-10]
VKLVWAQFAVTDRVRIFGHIEADNPRAAVRVDEQIARAVRRLLDFPESGRPGRVAGTREMVVPRTPYIAAYVVTSDRIRI
LRVLHGAQIWPDEIADDTDFP

Download         Length: 306 bp

>T37124 NZ_AP023263:545962-546267 [Mesorhizobium sp. L-8-10]
GTGAAGCTTGTCTGGGCACAATTTGCCGTTACGGATCGCGTCAGAATCTTCGGCCACATCGAAGCCGACAATCCGAGGGC
AGCGGTTCGAGTAGACGAGCAAATCGCTCGTGCGGTGAGGCGCCTGCTCGATTTTCCCGAAAGCGGACGTCCCGGCCGGG
TCGCAGGAACACGCGAGATGGTTGTACCTCGCACGCCCTACATCGCTGCCTATGTCGTGACGTCCGACAGGATTCGCATC
TTGCGTGTCCTCCACGGAGCACAGATCTGGCCGGACGAGATTGCCGACGACACCGATTTTCCGTGA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10917.33 Da        Isoelectric Point: 4.5141

>AT37124 WP_202314476.1 NZ_AP023263:545663-545965 [Mesorhizobium sp. L-8-10]
MVSNALIQTRIDADIKDRATAVLENMGLTVSDAVRILLTRTANEGALPLELVTNSEAHDAWFRAKVLQALEDARPDVDDD
EAETQFVARRLAALGKTGKQ

Download         Length: 303 bp

>AT37124 NZ_AP023263:545663-545965 [Mesorhizobium sp. L-8-10]
ATGGTTTCAAACGCACTGATCCAGACACGCATCGACGCCGATATAAAGGACCGCGCGACGGCTGTGCTCGAGAACATGGG
CCTCACGGTCTCCGATGCGGTCCGCATTCTGCTGACACGTACCGCGAACGAAGGCGCCTTGCCGCTCGAACTCGTCACCA
ACAGCGAGGCCCATGATGCCTGGTTCCGCGCAAAGGTCCTGCAGGCGCTTGAGGATGCGCGGCCGGACGTGGACGACGAC
GAAGCGGAGACGCAGTTTGTGGCCCGACGGCTGGCCGCTTTGGGCAAGACCGGCAAACAGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References