37123

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 361437..362131 Replicon chromosome
Accession NZ_AP023263
Organism Mesorhizobium sp. L-8-10

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JN280_RS01610 Protein ID WP_202309804.1
Coordinates 361709..362131 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JN280_RS01605 Protein ID WP_202309803.1
Coordinates 361437..361712 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN280_RS01575 356440..356943 - 504 WP_202309797.1 DUF4411 family protein -
JN280_RS01580 356940..358133 - 1194 WP_202309798.1 ImmA/IrrE family metallo-endopeptidase -
JN280_RS01585 358397..359113 + 717 WP_202309799.1 ribonuclease PH -
JN280_RS01590 359127..359537 + 411 WP_202309800.1 VOC family protein -
JN280_RS01595 359537..360184 + 648 WP_202309801.1 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase -
JN280_RS01600 360181..361344 + 1164 WP_202309802.1 coproporphyrinogen III oxidase -
JN280_RS01605 361437..361712 + 276 WP_202309803.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JN280_RS01610 361709..362131 + 423 WP_202309804.1 type II toxin-antitoxin system VapC family toxin Toxin
JN280_RS01615 362244..363143 + 900 WP_202309805.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
JN280_RS01620 363133..363498 + 366 WP_202309806.1 YraN family protein -
JN280_RS01625 363575..364399 + 825 WP_202309807.1 cyclase family protein -
JN280_RS01630 364482..365852 - 1371 WP_202309808.1 cytochrome P450 -
JN280_RS01635 366087..366656 + 570 WP_202309809.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-127)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(13-78)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15671.99 Da        Isoelectric Point: 4.7790

>T37123 WP_202309804.1 NZ_AP023263:361709-362131 [Mesorhizobium sp. L-8-10]
VSYLLDTNVLSEVRRPAPSPKVLAWLDEVDEDRSFISVISLAELRRGVLLMDDGRRREALAAWLVHDLPDRFAGRILPID
PETAERWGDLMAESQKIGRALSTMDGFLAATALGRQLTLVTRNTKDFASFGVPLLNPWEL

Download         Length: 423 bp

>T37123 NZ_AP023263:361709-362131 [Mesorhizobium sp. L-8-10]
GTGAGCTACCTGCTGGATACCAACGTCCTGTCTGAAGTCCGACGTCCGGCGCCAAGCCCAAAGGTTCTCGCCTGGCTCGA
TGAAGTCGATGAGGACAGGTCGTTCATAAGCGTCATTTCACTCGCTGAGCTTCGTCGTGGCGTTCTCCTGATGGACGATG
GGCGACGAAGGGAGGCGCTCGCTGCCTGGCTGGTGCATGATCTCCCCGACCGTTTCGCCGGCCGGATCCTACCAATCGAC
CCTGAGACCGCCGAGCGATGGGGAGATCTCATGGCCGAAAGCCAGAAGATCGGAAGGGCGCTTTCAACGATGGACGGGTT
CCTGGCCGCGACCGCACTGGGCAGGCAACTCACTCTGGTGACGCGAAACACCAAGGACTTCGCGTCCTTTGGGGTTCCTC
TTCTCAACCCATGGGAGCTGTAG

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9931.22 Da        Isoelectric Point: 7.2053

>AT37123 WP_202309803.1 NZ_AP023263:361437-361712 [Mesorhizobium sp. L-8-10]
MTTPETGPAEAATWTLARAKAKLSEVVDRAQAEPQLITRNGKPSAVIVSAEEWARKTTRKGSLADFLLNSPLRGTDIEID
RHHDAPRDIAL

Download         Length: 276 bp

>AT37123 NZ_AP023263:361437-361712 [Mesorhizobium sp. L-8-10]
ATGACTACGCCTGAGACAGGCCCGGCCGAAGCTGCAACGTGGACTCTGGCGCGGGCAAAGGCAAAGCTCTCCGAGGTCGT
TGACCGCGCCCAGGCTGAGCCCCAGTTGATCACACGCAACGGCAAGCCGAGTGCGGTGATCGTCTCAGCCGAAGAATGGG
CGCGCAAGACAACGCGCAAGGGAAGCCTTGCCGACTTCCTGCTCAATTCACCATTGCGTGGCACCGATATTGAGATAGAT
CGGCATCACGACGCACCGCGTGACATAGCTCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References