Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 6610564..6611117 Replicon chromosome
Accession NZ_AP023262
Organism Mesorhizobium sp. L-8-3

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag JN302_RS30660 Protein ID WP_202308112.1
Coordinates 6610564..6610851 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JN302_RS30665 Protein ID WP_202308113.1
Coordinates 6610839..6611117 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN302_RS30640 6605791..6606783 + 993 WP_202330187.1 substrate-binding domain-containing protein -
JN302_RS30645 6606945..6607895 + 951 WP_202308109.1 sugar-binding protein -
JN302_RS30650 6607993..6609513 + 1521 WP_202330188.1 sugar ABC transporter ATP-binding protein -
JN302_RS30655 6609510..6610472 + 963 WP_202330189.1 ABC transporter permease -
JN302_RS30660 6610564..6610851 - 288 WP_202308112.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JN302_RS30665 6610839..6611117 - 279 WP_202308113.1 CopG family ribbon-helix-helix protein Antitoxin
JN302_RS30670 6611189..6611827 - 639 WP_202330190.1 maleylacetoacetate isomerase -
JN302_RS30675 6611824..6612024 - 201 WP_202308115.1 DUF2783 domain-containing protein -
JN302_RS30680 6612028..6613623 - 1596 WP_202330191.1 FAD-dependent oxidoreductase -
JN302_RS30685 6613755..6614720 - 966 WP_202330192.1 MBL fold metallo-hydrolase -
JN302_RS30690 6614726..6615745 - 1020 WP_202330193.1 fumarylacetoacetate hydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10834.37 Da        Isoelectric Point: 9.8844

>T37121 WP_202308112.1 NZ_AP023262:c6610851-6610564 [Mesorhizobium sp. L-8-3]
MPQVIFAPAAIRDMQRLWDFLRPKSADAVRRAGETIRQGVRALGTHPRMGRLVEGLPEQYREWQIDFGDSGYVARVDDDA
VTILAVRHQKEAGFR

Download         Length: 288 bp

>T37121 NZ_AP023262:c6610851-6610564 [Mesorhizobium sp. L-8-3]
ATGCCACAAGTGATATTTGCCCCGGCCGCGATCCGGGACATGCAGCGGCTGTGGGATTTTCTCCGACCCAAGAGCGCCGA
TGCTGTGAGAAGGGCGGGTGAGACGATCAGGCAAGGCGTGCGGGCATTGGGCACGCATCCGCGGATGGGTCGTCTTGTCG
AAGGCCTGCCCGAACAATACCGGGAATGGCAAATCGACTTCGGGGATAGCGGCTATGTTGCCCGTGTCGATGATGATGCC
GTAACGATCTTGGCTGTACGACATCAAAAGGAGGCGGGATTCCGATGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10694.04 Da        Isoelectric Point: 6.7230

>AT37121 WP_202308113.1 NZ_AP023262:c6611117-6610839 [Mesorhizobium sp. L-8-3]
MATATSIKLDDELKGRVKQLTESRRRTSHWIMREAIAQYVEREEKREALRQDTLKAWEEFQATGLHATAEEGDKWLASWG
TEGERPVPICHK

Download         Length: 279 bp

>AT37121 NZ_AP023262:c6611117-6610839 [Mesorhizobium sp. L-8-3]
ATGGCAACAGCAACATCCATCAAACTCGATGACGAGTTGAAAGGGCGGGTGAAACAGCTCACCGAGTCTCGCCGCCGTAC
CTCGCACTGGATCATGCGCGAAGCCATAGCGCAGTATGTCGAGCGGGAGGAAAAGCGCGAAGCATTGCGGCAGGACACGC
TCAAAGCATGGGAAGAATTTCAGGCGACTGGCCTGCACGCCACGGCAGAGGAAGGCGACAAGTGGCTTGCGAGTTGGGGA
ACTGAAGGCGAACGTCCCGTGCCCATATGCCACAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References