Detailed information of TA system TA037116

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yoeB-relE/YoeB-YefM
• Location: 2999541..3000046
• Replicon: chromosome
• Accession: NZ_AP023262
• Organism: Mesorhizobium sp. L-8-3

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: JN302_RS14070
• Protein ID: WP_202333302.1
• Coordinates: 2999792..3000046 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: JN302_RS14065
• Protein ID: WP_202333301.1
• Coordinates: 2999541..2999795 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JN302_RS14060	2997940..2999394	+	1455	WP_202333300.1	glutamate synthase subunit beta	-
JN302_RS14065	2999541..2999795	+	255	WP_202333301.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
JN302_RS14070	2999792..3000046	+	255	WP_202333302.1	Txe/YoeB family addiction module toxin	Toxin
JN302_RS14075	3000219..3001400	-	1182	WP_202334284.1	DUF459 domain-containing protein	-
JN302_RS14080	3001601..3002824	-	1224	WP_202333303.1	lytic murein transglycosylase	-
JN302_RS14085	3003191..3004075	+	885	WP_202333304.1	UTP--glucose-1-phosphate uridylyltransferase GalU	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10047.57 Da
• Isoelectric Point: 9.7083

>T37116 WP_202333302.1 NZ_AP023262:2999792-3000046 [Mesorhizobium sp. L-8-3]
VKLIFSERAWEDCLHWQTHDRKLLLRINDLIKECSRTPFAGSGKPEPLRGALSGWWSRRISREHRLVYRPTEEGLLIAQC
RYHY

Nucleotide

• Length: 255 bp

>T37116 NZ_AP023262:2999792-3000046 [Mesorhizobium sp. L-8-3]
GTGAAACTCATCTTCAGCGAGCGCGCCTGGGAGGACTGCCTCCATTGGCAGACCCATGACCGCAAGCTGCTCCTGCGCAT
AAACGATCTCATCAAAGAGTGCAGCCGGACGCCGTTCGCCGGCAGCGGCAAGCCGGAACCGTTGCGCGGCGCCCTATCCG
GCTGGTGGTCGCGGCGGATCTCTCGGGAGCACCGGCTGGTGTACCGACCCACCGAGGAGGGGCTGCTGATCGCGCAGTGC
CGGTATCATTATTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9559.79 Da
• Isoelectric Point: 5.8768

>AT37116 WP_202333301.1 NZ_AP023262:2999541-2999795 [Mesorhizobium sp. L-8-3]
MRTTSYSDLRRNLAAMIDRVNADHEPVIITRDRGKPTAVLMSMEDFASYEETRYLLKSPRNAERLAESIAELDAGKGTKR
ELSE

Nucleotide

• Length: 255 bp

>AT37116 NZ_AP023262:2999541-2999795 [Mesorhizobium sp. L-8-3]
ATGCGTACCACCTCCTACAGCGACCTTCGCAGGAATCTCGCGGCCATGATCGACCGGGTCAATGCCGATCATGAGCCTGT
TATAATCACACGCGACCGCGGCAAGCCTACGGCGGTGTTGATGTCGATGGAGGACTTCGCCTCCTATGAGGAAACTCGGT
ATCTGCTGAAGAGTCCCCGCAACGCGGAGCGACTTGCCGAATCGATCGCAGAGCTTGACGCGGGCAAGGGAACGAAGCGT
GAGCTTTCGGAGTGA