Detailed information of TA system TA037113

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): slvAT/RES(toxin)
• Location: 1577739..1578646
• Replicon: chromosome
• Accession: NZ_AP023262
• Organism: Mesorhizobium sp. L-8-3

Toxin (Protein)

• Gene name: slvT
• Uniprot ID: -
• Locus tag: JN302_RS07310
• Protein ID: WP_202332468.1
• Coordinates: 1578122..1578646 (+)
• Length: 175 a.a.

Antitoxin (Protein)

• Gene name: slvA
• Uniprot ID: -
• Locus tag: JN302_RS07305
• Protein ID: WP_202332467.1
• Coordinates: 1577739..1578125 (+)
• Length: 129 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JN302_RS07280	1573358..1574026	+	669	WP_202315021.1	haloacid dehalogenase type II	-
JN302_RS07285	1574031..1575101	+	1071	WP_202332464.1	phosphotransferase	-
JN302_RS07290	1575138..1576466	+	1329	WP_202306061.1	aspartate aminotransferase family protein	-
JN302_RS07295	1576541..1576933	-	393	WP_202332465.1	hypothetical protein	-
JN302_RS07300	1576984..1577301	+	318	WP_202332466.1	hypothetical protein	-
JN302_RS07305	1577739..1578125	+	387	WP_202332467.1	hypothetical protein	Antitoxin
JN302_RS07310	1578122..1578646	+	525	WP_202332468.1	RES family NAD+ phosphorylase	Toxin
JN302_RS07315	1578700..1579257	-	558	Protein_1451	SMC-Scp complex subunit ScpB	-
JN302_RS07320	1579324..1580023	+	700	WP_202332469.1	IS6 family transposase	-
JN302_RS07325	1580087..1580275	+	189	Protein_1453	DDE-type integrase/transposase/recombinase	-
JN302_RS07330	1580363..1581625	+	1263	WP_202332470.1	TRAP transporter large permease	-
JN302_RS07340	1582465..1582686	-	222	Protein_1456	transposase	-
JN302_RS07345	1582870..1583157	-	288	Protein_1457	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (12-167)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 175 a.a.
• Molecular weight: 19190.64 Da
• Isoelectric Point: 6.2181

>T37113 WP_202332468.1 NZ_AP023262:1578122-1578646 [Mesorhizobium sp. L-8-3]
VKVAQIGPDEIFHRYLTPKWAFLPTSGAGAATDGGRFNRPSVEALYLSRSTQTALDEYRQGASITPPATLAAYKITLAEV
ADLSQGFDPDIWDGAWQEWDCAWRQIARIERKIPPSWKLADLVITAGLRGILFPSLRHAGGTNLVIFPANLVDGDHVAVH
DPDHRLPHDQSSWP

Nucleotide

• Length: 525 bp

>T37113 NZ_AP023262:1578122-1578646 [Mesorhizobium sp. L-8-3]
GTGAAGGTCGCCCAAATCGGTCCCGACGAGATCTTCCATCGCTACCTGACACCCAAATGGGCTTTCCTGCCTACCAGTGG
CGCAGGAGCGGCGACAGACGGCGGGCGCTTCAATCGGCCCAGCGTCGAAGCACTCTATCTGTCCCGTTCGACCCAGACGG
CTCTCGATGAATACAGGCAGGGCGCCAGCATCACCCCGCCAGCCACCCTTGCCGCCTACAAGATCACCCTCGCCGAAGTA
GCCGACCTTTCGCAGGGATTCGACCCGGACATCTGGGACGGCGCCTGGCAAGAATGGGATTGTGCCTGGCGCCAGATCGC
CCGCATCGAGAGGAAAATCCCGCCCTCGTGGAAGCTCGCGGATCTGGTCATCACTGCAGGGCTGCGCGGCATCCTGTTTC
CGTCGCTGCGTCATGCCGGCGGCACCAATCTGGTGATCTTTCCGGCCAATCTTGTCGACGGCGATCATGTCGCGGTTCAT
GATCCCGATCACCGGCTGCCGCACGACCAGTCGTCCTGGCCCTGA

Antitoxin

Protein

• Length: 129 a.a.
• Molecular weight: 14108.05 Da
• Isoelectric Point: 9.8605

>AT37113 WP_202332467.1 NZ_AP023262:1577739-1578125 [Mesorhizobium sp. L-8-3]
MTRAQLAQSKVVSGFVDSLQEPRTPYISPKRLSQALGVKVANLAQLTGVHRNTLRNPSSERLQGRMREMVKVISAATELT
GDVDKAIYWYRNEPIADYGHRTAAELVADGQVEAVLAFIRDLENGARG

Nucleotide

• Length: 387 bp

>AT37113 NZ_AP023262:1577739-1578125 [Mesorhizobium sp. L-8-3]
ATGACCCGCGCACAGCTCGCACAATCGAAAGTGGTTTCAGGCTTCGTCGACAGCCTGCAGGAGCCGCGCACGCCCTACAT
CTCGCCGAAGCGCCTGTCGCAGGCGCTTGGCGTGAAGGTGGCCAACCTGGCCCAGCTGACCGGTGTCCACCGCAACACAC
TGCGCAATCCGTCATCGGAGCGCCTGCAGGGCCGGATGCGCGAGATGGTCAAGGTGATTTCGGCCGCGACGGAGCTCACC
GGCGACGTCGACAAGGCGATCTACTGGTATCGCAACGAACCGATCGCCGACTATGGCCATCGCACGGCGGCCGAGCTCGT
CGCCGACGGCCAGGTCGAGGCGGTTCTGGCCTTCATCCGGGATCTCGAGAACGGGGCGCGCGGGTGA