Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 1118565..1119139 Replicon chromosome
Accession NZ_AP023262
Organism Mesorhizobium sp. L-8-3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JN302_RS05135 Protein ID WP_202310441.1
Coordinates 1118565..1118948 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JN302_RS05140 Protein ID WP_202332178.1
Coordinates 1118945..1119139 (-) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN302_RS05110 1114196..1115002 - 807 WP_202310433.1 ABC transporter permease -
JN302_RS05115 1115005..1115730 - 726 WP_202310435.1 ABC transporter permease -
JN302_RS05120 1115869..1116648 - 780 WP_202310437.1 transporter substrate-binding domain-containing protein -
JN302_RS05125 1116679..1117491 - 813 WP_202332176.1 ABC transporter ATP-binding protein -
JN302_RS05130 1117712..1118560 + 849 WP_202314554.1 amidinotransferase -
JN302_RS05135 1118565..1118948 - 384 WP_202310441.1 type II toxin-antitoxin system VapC family toxin Toxin
JN302_RS05140 1118945..1119139 - 195 WP_202332178.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
JN302_RS05145 1120119..1120852 - 734 Protein_1026 SMP-30/gluconolactonase/LRE family protein -
JN302_RS05150 1121233..1121649 - 417 WP_202310447.1 carboxymuconolactone decarboxylase family protein -
JN302_RS05155 1121779..1122474 + 696 WP_202310448.1 GntR family transcriptional regulator -
JN302_RS05160 1122511..1123266 - 756 WP_202332180.1 SDR family oxidoreductase -
JN302_RS05165 1123289..1124077 - 789 WP_202310452.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 13736.77 Da        Isoelectric Point: 6.4858

>T37112 WP_202310441.1 NZ_AP023262:c1118948-1118565 [Mesorhizobium sp. L-8-3]
VKLADTGIWIDHFRHADAELSRTLADDMMLCHPVVIGELALGSLRNRASTLAYLEALREIAVATHAEVMEMVERHQLCSM
GIDYSGAHLLASTLIDGRAELWTRDKRLGAAARKAGVRLASEGGTAG

Download         Length: 384 bp

>T37112 NZ_AP023262:c1118948-1118565 [Mesorhizobium sp. L-8-3]
GTGAAGCTTGCCGACACGGGAATCTGGATCGACCACTTCCGTCACGCCGACGCCGAATTGTCGCGGACCCTCGCTGACGA
CATGATGCTGTGCCATCCGGTCGTCATCGGCGAACTTGCTTTGGGAAGCCTGCGCAATCGAGCGTCCACTCTCGCGTATC
TGGAGGCTCTTCGTGAGATCGCCGTGGCCACCCATGCGGAGGTGATGGAAATGGTCGAGCGGCATCAACTCTGCAGCATG
GGCATCGACTATTCCGGCGCGCATCTCCTTGCATCAACTCTGATTGACGGCCGGGCCGAGTTGTGGACCCGCGATAAGCG
TCTGGGCGCTGCGGCCCGCAAGGCCGGCGTGAGGCTCGCAAGCGAAGGCGGCACAGCAGGGTGA

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7032.07 Da        Isoelectric Point: 10.6723

>AT37112 WP_202332178.1 NZ_AP023262:c1119139-1118945 [Mesorhizobium sp. L-8-3]
MRSTINLDDRLLEEAKALTGTKETAAVVRQALETLVRVEAGRRLIALGGTMTDAEAAPRRRPDR

Download         Length: 195 bp

>AT37112 NZ_AP023262:c1119139-1118945 [Mesorhizobium sp. L-8-3]
ATGCGATCGACGATCAACCTGGACGACCGGCTCCTGGAAGAAGCAAAGGCGCTGACCGGGACGAAGGAGACGGCCGCGGT
GGTGCGCCAGGCGCTCGAGACATTGGTACGTGTCGAAGCGGGCAGGCGTCTCATCGCCTTGGGCGGAACAATGACCGATG
CCGAGGCAGCACCGCGCCGGCGGCCTGATCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References