Detailed information of TA system TA037111

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 908126..909137
• Replicon: chromosome
• Accession: NZ_AP023262
• Organism: Mesorhizobium sp. L-8-3

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: JN302_RS04205
• Protein ID: WP_202334181.1
• Coordinates: 908126..908695 (-)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: JN302_RS04210
• Protein ID: WP_202310248.1
• Coordinates: 908697..909137 (-)
• Length: 147 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JN302_RS04180	903239..903985	-	747	WP_202331957.1	GntR family transcriptional regulator	-
JN302_RS04185	903982..904857	-	876	WP_202331959.1	ROK family protein	-
JN302_RS04190	904854..905702	-	849	WP_202310245.1	carbohydrate ABC transporter permease	-
JN302_RS04195	905699..906595	-	897	WP_202310246.1	sugar ABC transporter permease	-
JN302_RS04200	906659..907954	-	1296	WP_202331961.1	extracellular solute-binding protein	-
JN302_RS04205	908126..908695	-	570	WP_202334181.1	PIN domain-containing protein	Toxin
JN302_RS04210	908697..909137	-	441	WP_202310248.1	helix-turn-helix domain-containing protein	Antitoxin
JN302_RS04215	909412..910335	-	924	WP_202331963.1	alpha/beta hydrolase	-
JN302_RS04220	910512..914129	-	3618	WP_202331965.1	hydantoinase B/oxoprolinase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (6-113)

Antitoxin

• Helix-turn-helix domain, group 17 (76-124)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21233.49 Da
• Isoelectric Point: 4.8050

>T37111 WP_202334181.1 NZ_AP023262:c908695-908126 [Mesorhizobium sp. L-8-3]
IAGYTVILDACVLYPAPLRDFLLELAGSGMFRARWSDIIHDEWIRNLLKARPDLSRDRLMRTRRLMDDSVLGSLVEGFEE
LIPVLELPDPDDRHVLAAAIHSGSDAIVTVNLKDFPAEVAKRYELEILHPDDFLYQQFGLDPAAVVLAARNCRARLKSPP
RSGGEYLATLEAQGLPLLVSELRKFEDLL

Nucleotide

• Length: 570 bp

>T37111 NZ_AP023262:c908695-908126 [Mesorhizobium sp. L-8-3]
ATCGCCGGCTACACGGTCATTCTCGACGCGTGCGTGCTGTATCCTGCACCGCTGCGCGATTTCCTGCTAGAACTTGCCGG
AAGCGGCATGTTTCGAGCACGTTGGTCCGATATCATCCACGACGAATGGATCCGCAACCTGTTGAAGGCTCGTCCCGATC
TCAGCCGCGATCGTCTCATGCGTACGCGTCGGCTGATGGACGACAGTGTGCTCGGGAGCCTGGTCGAGGGGTTCGAAGAG
CTGATCCCCGTGTTGGAGTTGCCCGATCCTGACGATCGGCATGTGCTTGCCGCGGCGATACACAGTGGAAGCGACGCGAT
CGTCACCGTCAACCTCAAGGATTTTCCTGCCGAGGTTGCAAAACGCTACGAGCTGGAAATTCTTCACCCTGACGATTTTC
TCTATCAGCAGTTCGGGCTTGATCCGGCGGCAGTTGTCCTTGCTGCCCGAAATTGCCGTGCGCGGTTGAAAAGCCCGCCG
AGAAGCGGCGGCGAGTACCTCGCTACGCTCGAGGCGCAGGGCCTGCCTTTGCTCGTCAGCGAACTGCGCAAGTTCGAAGA
CCTGCTCTGA

Antitoxin

Protein

• Length: 147 a.a.
• Molecular weight: 16229.58 Da
• Isoelectric Point: 7.5242

>AT37111 WP_202310248.1 NZ_AP023262:c909137-908697 [Mesorhizobium sp. L-8-3]
MLLEHPDTIVPTADDAELAAKASRILSRRGKNGLRIRLDDGEELTLPVAAARLLTHLLTEMSQGNAVTLIPVHAELTTRQ
AAEYLNVSRPHVVKLLEQSRIPYHKVGTHRRIRFSDLEAFKRQQETARGQALDALAAEAQEMGMGY

Nucleotide

• Length: 441 bp

>AT37111 NZ_AP023262:c909137-908697 [Mesorhizobium sp. L-8-3]
ATGTTGCTCGAACACCCCGATACGATCGTGCCCACGGCCGACGATGCGGAATTGGCGGCTAAGGCGAGCCGGATCCTGTC
GCGTCGCGGCAAGAACGGCCTGCGCATCCGCCTCGACGATGGTGAGGAACTTACCCTTCCCGTCGCGGCGGCAAGATTGC
TTACGCATCTGCTCACCGAAATGTCACAGGGAAACGCGGTTACTCTGATCCCGGTGCATGCGGAACTCACGACACGCCAG
GCGGCTGAATATCTCAACGTTTCGCGGCCCCATGTGGTCAAGCTGCTGGAGCAATCCAGGATTCCCTACCACAAGGTTGG
AACGCACAGGCGCATAAGGTTCAGCGATCTTGAAGCCTTCAAGCGGCAGCAGGAAACCGCGCGAGGTCAGGCTCTCGATG
CCTTGGCCGCCGAAGCCCAGGAAATGGGGATGGGCTATTAG