Detailed information of TA system TA037107

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): slvAT/RES(toxin)
• Location: 210170..211083
• Replicon: plasmid MesoLjLa3
• Accession: NZ_AP023259
• Organism: Mesorhizobium sp. L-2-11

Toxin (Protein)

• Gene name: slvT
• Uniprot ID: -
• Locus tag: JG739_RS33785
• Protein ID: WP_199202882.1
• Coordinates: 210170..210700 (-)
• Length: 177 a.a.

Antitoxin (Protein)

• Gene name: slvA
• Uniprot ID: -
• Locus tag: JG739_RS33790
• Protein ID: WP_199202883.1
• Coordinates: 210697..211083 (-)
• Length: 129 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JG739_RS33755	205694..206825	-	1132	Protein_184	site-specific integrase	-
JG739_RS33760	207061..207357	+	297	WP_199202879.1	hypothetical protein	-
JG739_RS33765	207670..208029	+	360	WP_038654666.1	type II toxin-antitoxin system RelE/ParE family toxin	-
JG739_RS33770	208019..208342	+	324	WP_038654663.1	DNA-binding transcriptional regulator	-
JG739_RS33775	208461..209414	+	954	WP_199202880.1	DUF1403 family protein	-
JG739_RS33780	209417..210139	+	723	WP_199202881.1	SMC-Scp complex subunit ScpB	-
JG739_RS33785	210170..210700	-	531	WP_199202882.1	RES family NAD+ phosphorylase	Toxin
JG739_RS33790	210697..211083	-	387	WP_199202883.1	hypothetical protein	Antitoxin
JG739_RS33795	211475..212479	+	1005	WP_202367921.1	hypothetical protein	-
JG739_RS33800	212476..212961	+	486	WP_199202885.1	hypothetical protein	-
JG739_RS33805	212963..214840	+	1878	WP_199202886.1	hypothetical protein	-
JG739_RS33810	214904..215866	+	963	WP_199202887.1	DUF4238 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	hsiC1/vipB	1..247505	247505

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (12-167)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 177 a.a.
• Molecular weight: 19271.81 Da
• Isoelectric Point: 5.9840

>T37107 WP_199202882.1 NZ_AP023259:c210700-210170 [Mesorhizobium sp. L-2-11]
VKVTRVGPDEIFHRYLTPKWAFLPTSGAGAAIDGGRFNRPGVEALYLSRSTQTALDEYKQGASIVPPATLAAYKITLAEV
ADLSQGFDPEIWDSAWQEWDCAWRQIARIDKKIPPSWKLADPIITAGLRGILFPSLRHAGGTNLVIFPANLVDGDHVAVH
DPDDRLPHDQSSSLSC

Nucleotide

• Length: 531 bp

>T37107 NZ_AP023259:c210700-210170 [Mesorhizobium sp. L-2-11]
GTGAAGGTCACCCGCGTCGGGCCGGACGAGATCTTCCATCGCTATCTGACACCCAAATGGGCCTTCCTGCCCACCAGCGG
TGCAGGCGCGGCGATCGACGGCGGTCGTTTCAACCGGCCAGGCGTCGAAGCACTCTATCTGTCCCGTTCGACCCAGACGG
CTCTTGACGAATATAAGCAGGGCGCCAGCATCGTCCCGCCGGCAACGCTTGCCGCCTACAAGATCACGCTCGCTGAGGTG
GCCGACCTTTCGCAGGGATTCGACCCGGAGATCTGGGACAGCGCTTGGCAGGAATGGGATTGTGCCTGGCGCCAGATCGC
TCGCATCGACAAAAAAATCCCGCCATCGTGGAAGCTCGCGGACCCGATCATCACGGCCGGGCTTCGCGGCATCCTGTTCC
CGTCGCTGCGTCACGCCGGCGGCACCAATCTGGTGATCTTTCCGGCCAATCTTGTCGACGGCGACCATGTCGCGGTTCAC
GATCCCGATGACCGGCTGCCGCACGACCAGTCATCTTCCCTGAGTTGCTAG

Antitoxin

Protein

• Length: 129 a.a.
• Molecular weight: 14042.89 Da
• Isoelectric Point: 8.5217

>AT37107 WP_199202883.1 NZ_AP023259:c211083-210697 [Mesorhizobium sp. L-2-11]
MTHAQLAHSTAVSGFVDSLQEPRTPYISPKRLSQALGVKVANLAQLTGVHRNTLRNPSSERLQGRMREMVKVISAATELT
GDVDKAIYWYRNEPIADYGHRTAAELVADGQVEAVLAFIRDLENGARG

Nucleotide

• Length: 387 bp

>AT37107 NZ_AP023259:c211083-210697 [Mesorhizobium sp. L-2-11]
ATGACGCACGCACAGCTCGCACATTCCACCGCGGTCTCAGGCTTTGTCGATAGCCTTCAGGAGCCGCGCACGCCTTATAT
CTCGCCGAAACGCCTGTCGCAGGCGCTTGGCGTGAAGGTGGCCAATCTGGCGCAATTGACCGGCGTCCATCGCAACACGC
TGCGCAATCCCTCATCTGAGCGCCTGCAGGGCCGGATGCGCGAGATGGTGAAGGTGATCTCGGCCGCGACGGAGCTCACC
GGCGACGTCGACAAGGCAATCTACTGGTATCGCAATGAGCCGATCGCCGACTATGGCCATCGCACGGCGGCCGAACTCGT
CGCGGACGGCCAGGTCGAAGCAGTCCTGGCCTTCATCCGGGATCTCGAGAACGGGGCGCGCGGGTGA