Detailed information of TA system TA037105

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-Xre
• Location: 5388647..5389517
• Replicon: chromosome
• Accession: NZ_AP023257
• Organism: Mesorhizobium sp. L-2-11

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: JG739_RS25720
• Protein ID: WP_202363972.1
• Coordinates: 5388647..5389153 (-)
• Length: 169 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: JG739_RS25725
• Protein ID: WP_202363973.1
• Coordinates: 5389146..5389517 (-)
• Length: 124 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JG739_RS25705	5384982..5385860	-	879	WP_202363969.1	cytochrome c oxidase subunit II	-
JG739_RS25710	5386236..5386841	+	606	WP_202363970.1	invasion associated locus B family protein	-
JG739_RS25715	5387082..5388494	+	1413	WP_202363971.1	metalloprotease TldD	-
JG739_RS25720	5388647..5389153	-	507	WP_202363972.1	RES domain-containing protein	Toxin
JG739_RS25725	5389146..5389517	-	372	WP_202363973.1	MbcA/ParS/Xre antitoxin family protein	Antitoxin
JG739_RS25730	5389603..5390844	-	1242	WP_202363974.1	class I SAM-dependent RNA methyltransferase	-
JG739_RS25735	5390841..5391635	-	795	WP_202363975.1	TlyA family RNA methyltransferase	-
JG739_RS25740	5391809..5392210	+	402	WP_202363976.1	GFA family protein	-
JG739_RS25745	5392331..5392993	-	663	WP_202363977.1	NAD(P)H-dependent oxidoreductase	-
JG739_RS25750	5393092..5393955	+	864	WP_202363978.1	LysR family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (8-161)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (71-120)

Sequences

Toxin

Protein

• Length: 169 a.a.
• Molecular weight: 18731.35 Da
• Isoelectric Point: 7.9514

>T37105 WP_202363972.1 NZ_AP023257:c5389153-5388647 [Mesorhizobium sp. L-2-11]
MPENRLSLWRAFVPRWAHLALSGEGAARFGGRWNPGGTPTIYAARELSTAWAEYNQGFVQHPALIAQLALSGARLADLTD
TDVLTKLGVKADIHRCEWRDIMDQGLVPETHTLRDRLLADGQHGVIYPSFMSPGGTCVALWRWNESNAPRLKVIDPDHRL
PKTPASWL

Nucleotide

• Length: 507 bp

>T37105 NZ_AP023257:c5389153-5388647 [Mesorhizobium sp. L-2-11]
ATGCCTGAAAACAGACTGAGCCTATGGCGTGCCTTCGTGCCGCGTTGGGCGCATCTGGCGCTTTCCGGCGAAGGAGCGGC
CCGCTTTGGCGGTCGCTGGAACCCGGGAGGCACCCCGACAATCTATGCCGCACGGGAATTGTCCACTGCTTGGGCGGAGT
ACAATCAGGGCTTTGTCCAACATCCGGCGCTGATTGCGCAACTCGCACTTTCAGGCGCGCGGCTGGCCGATCTGACGGAC
ACTGACGTGCTGACCAAGCTCGGCGTGAAGGCAGACATTCACCGATGTGAATGGCGCGACATCATGGATCAAGGCCTGGT
GCCGGAGACGCACACGCTGAGAGATCGCCTGCTTGCCGATGGGCAGCACGGCGTGATCTACCCCTCCTTCATGTCGCCGG
GCGGCACATGCGTCGCGCTGTGGCGATGGAACGAGAGCAACGCACCCCGTCTGAAGGTCATCGACCCCGACCATCGCCTG
CCGAAAACGCCGGCTTCATGGCTTTAG

Antitoxin

Protein

• Length: 124 a.a.
• Molecular weight: 13212.25 Da
• Isoelectric Point: 9.9467

>AT37105 WP_202363973.1 NZ_AP023257:c5389517-5389146 [Mesorhizobium sp. L-2-11]
MNTAALDIRASQFGDERTPFLSARRVAELLGVNLTELAGLIGVARNTLAAKTSARKVDAALSPIVRILAMAGEMAGDEQR
AAIWFKHQPIPGWAGKTAYDLVREGKSDKVLAYLEAVRSGIYA

Nucleotide

• Length: 372 bp

>AT37105 NZ_AP023257:c5389517-5389146 [Mesorhizobium sp. L-2-11]
ATGAATACCGCAGCTCTCGATATCAGAGCATCGCAATTTGGCGACGAGCGGACGCCATTTCTTTCGGCAAGACGGGTGGC
TGAACTGCTGGGCGTCAATCTGACCGAACTGGCGGGCCTGATCGGCGTCGCGCGCAACACGCTTGCCGCCAAGACCAGCG
CGCGCAAGGTCGACGCCGCATTGAGTCCGATTGTCCGTATCCTGGCGATGGCAGGCGAGATGGCCGGCGATGAACAGCGC
GCGGCGATCTGGTTCAAGCATCAGCCGATCCCCGGCTGGGCGGGAAAGACCGCCTACGATCTCGTTCGAGAGGGCAAGTC
GGACAAGGTGCTTGCCTATCTGGAGGCAGTCCGCTCCGGCATCTATGCCTGA