Detailed information of TA system TA037104

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pasABC/RelE(toxin)
• Location: 2957150..2957661
• Replicon: chromosome
• Accession: NZ_AP023257
• Organism: Mesorhizobium sp. L-2-11

Toxin (Protein)

• Gene name: pasB
• Uniprot ID: -
• Locus tag: JG739_RS14150
• Protein ID: WP_202366980.1
• Coordinates: 2957395..2957661 (+)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: JG739_RS14145
• Protein ID: WP_202366979.1
• Coordinates: 2957150..2957398 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JG739_RS14130	2953065..2954000	-	936	WP_202366976.1	alpha/beta hydrolase	-
JG739_RS14135	2954201..2955226	+	1026	WP_202366977.1	ribonuclease	-
JG739_RS14140	2955443..2957092	+	1650	WP_202366978.1	energy-dependent translational throttle protein EttA	-
JG739_RS14145	2957150..2957398	+	249	WP_202366979.1	hypothetical protein	Antitoxin
JG739_RS14150	2957395..2957661	+	267	WP_202366980.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
JG739_RS14155	2957658..2958452	+	795	WP_202366981.1	trans-aconitate 2-methyltransferase	-
JG739_RS14160	2958660..2959781	+	1122	WP_202366982.1	beta-ketoacyl-ACP synthase III	-
JG739_RS14165	2959924..2960541	+	618	WP_202366983.1	MOSC domain-containing protein	-
JG739_RS14170	2960554..2961207	-	654	Protein_2792	aminotransferase class IV	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-87)

Antitoxin

• Protein of unknown function DUF6290 (1-67)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10583.09 Da
• Isoelectric Point: 10.8167

>T37104 WP_202366980.1 NZ_AP023257:2957395-2957661 [Mesorhizobium sp. L-2-11]
MSWRVEFTRQAEKDIERLSTKDQRRILEFLHQRVSEHPNPRALAKGLTATKQEAWRFRVGDYRIIAQFEDSRLVVLVVEV
GNRREVYR

Nucleotide

• Length: 267 bp

>T37104 NZ_AP023257:2957395-2957661 [Mesorhizobium sp. L-2-11]
ATGAGTTGGCGTGTCGAGTTCACGCGGCAAGCCGAAAAGGATATCGAACGGCTTTCAACGAAAGATCAGCGGCGCATCCT
CGAATTCCTGCATCAAAGAGTTTCGGAGCACCCCAATCCAAGAGCGCTTGCCAAGGGCCTGACCGCTACCAAGCAAGAGG
CTTGGCGTTTTCGCGTCGGCGACTACAGAATCATCGCCCAATTCGAGGATAGCCGGCTTGTCGTGCTGGTTGTGGAGGTC
GGCAACCGTCGCGAGGTCTATCGATGA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9326.57 Da
• Isoelectric Point: 4.4065

>AT37104 WP_202366979.1 NZ_AP023257:2957150-2957398 [Mesorhizobium sp. L-2-11]
MITVKLPQEAETLLADMARASGRTVDQVAVEAILETIEDWQDARIAEERLRDDDGARIPLEDVIRKLELREATERRKKPA
AE

Nucleotide

• Length: 249 bp

>AT37104 NZ_AP023257:2957150-2957398 [Mesorhizobium sp. L-2-11]
ATGATCACGGTCAAATTGCCGCAAGAAGCCGAGACGCTGCTGGCCGATATGGCGAGGGCCAGCGGCCGTACGGTCGATCA
GGTTGCAGTTGAAGCGATTCTCGAGACCATCGAGGATTGGCAGGACGCGAGGATTGCGGAGGAACGCTTGAGGGATGACG
ACGGTGCTCGCATTCCGTTGGAAGACGTGATCCGGAAGCTTGAGCTTCGCGAAGCAACGGAACGGCGCAAGAAACCTGCC
GCTGAATGA