Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relE/YoeB-YefM
Location 1415102..1415607 Replicon chromosome
Accession NZ_AP023257
Organism Mesorhizobium sp. L-2-11

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag JG739_RS06835 Protein ID WP_202365807.1
Coordinates 1415102..1415356 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag JG739_RS06840 Protein ID WP_202365808.1
Coordinates 1415353..1415607 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG739_RS06800 1410722..1411363 + 642 WP_202365803.1 DNA-3-methyladenine glycosylase -
JG739_RS06805 1411492..1412049 + 558 WP_023797250.1 HNH endonuclease -
JG739_RS06810 1412303..1412821 - 519 WP_202367365.1 disulfide bond formation protein B -
JG739_RS06815 1412968..1413555 - 588 WP_202365804.1 DedA family protein -
JG739_RS06825 1414038..1414646 - 609 WP_202365805.1 hypothetical protein -
JG739_RS06830 1414852..1415031 - 180 WP_202365806.1 hypothetical protein -
JG739_RS06835 1415102..1415356 - 255 WP_202365807.1 Txe/YoeB family addiction module toxin Toxin
JG739_RS06840 1415353..1415607 - 255 WP_202365808.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
JG739_RS06845 1415672..1416952 - 1281 WP_202365809.1 GNAT family N-acetyltransferase -
JG739_RS06850 1416952..1418352 - 1401 WP_202365810.1 lipopolysaccharide biosynthesis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10002.51 Da        Isoelectric Point: 9.5797

>T37101 WP_202365807.1 NZ_AP023257:c1415356-1415102 [Mesorhizobium sp. L-2-11]
VKLVFHERAWEDYLHWQATDPKLLLRINTLIKECSRTPLSGTGKPEPLRGPLSGWWSRRITQEHRLVYRATEDSLLIAQC
RYHY

Download         Length: 255 bp

>T37101 NZ_AP023257:c1415356-1415102 [Mesorhizobium sp. L-2-11]
GTGAAGCTCGTCTTCCACGAGCGCGCCTGGGAGGATTATCTGCACTGGCAAGCAACCGACCCGAAGCTGCTCTTGCGCAT
CAATACACTCATCAAGGAATGCAGTCGCACCCCGCTAAGCGGCACCGGCAAGCCGGAGCCATTACGCGGCCCTCTGTCGG
GCTGGTGGTCGCGGCGCATCACGCAGGAGCATCGCCTGGTCTACCGCGCCACCGAGGACAGCCTGCTCATTGCGCAGTGC
CGCTATCATTATTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9334.40 Da        Isoelectric Point: 4.6388

>AT37101 WP_202365808.1 NZ_AP023257:c1415607-1415353 [Mesorhizobium sp. L-2-11]
MRTTSYSDLRRNLAAMIDRVNADHEPVVITRDRGKPAAVLMSVEDFASYEETRYLLRSPGNAARLLEATVELDQGGGSEH
ELAE

Download         Length: 255 bp

>AT37101 NZ_AP023257:c1415607-1415353 [Mesorhizobium sp. L-2-11]
ATGCGTACCACATCCTACAGTGACCTGCGGCGCAATCTCGCCGCCATGATCGACCGCGTTAACGCGGACCATGAACCGGT
TGTCATCACGCGCGACCGCGGCAAGCCAGCGGCAGTGCTGATGTCGGTCGAAGACTTCGCCTCTTACGAGGAGACGCGCT
ATCTGCTGAGAAGCCCAGGCAACGCCGCGCGGCTGCTCGAAGCGACGGTGGAGTTGGACCAGGGCGGCGGCAGCGAGCAC
GAGCTTGCCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References