Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 11149..11948 Replicon plasmid MesoLj131c2
Accession NZ_AP023255
Organism Mesorhizobium sp. 131-3-5

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag JG747_RS32615 Protein ID WP_199201390.1
Coordinates 11149..11670 (-) Length 174 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag JG747_RS32620 Protein ID WP_128174838.1
Coordinates 11667..11948 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG747_RS32590 7433..8504 - 1072 Protein_6 hypothetical protein -
JG747_RS32595 8745..9029 - 285 WP_199201387.1 type II toxin-antitoxin system RelE/ParE family toxin -
JG747_RS32600 9026..9304 - 279 WP_128174847.1 antitoxin of toxin-antitoxin stability system -
JG747_RS32605 9537..9746 - 210 WP_199201388.1 hypothetical protein -
JG747_RS32610 10001..11146 - 1146 WP_199201389.1 site-specific integrase -
JG747_RS32615 11149..11670 - 522 WP_199201390.1 GNAT family N-acetyltransferase Toxin
JG747_RS32620 11667..11948 - 282 WP_128174838.1 DUF1778 domain-containing protein Antitoxin
JG747_RS32625 12145..13167 + 1023 WP_199201391.1 DUF1403 family protein -
JG747_RS32630 13173..13892 + 720 WP_199201392.1 SMC-Scp complex subunit ScpB -
JG747_RS32635 14243..15364 + 1122 WP_199201563.1 DUF3800 domain-containing protein -
JG747_RS32640 15793..16335 - 543 WP_199201393.1 His-Xaa-Ser repeat protein HxsA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - gmd 1..654771 654771


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(11-88)


Sequences

Toxin        


Download         Length: 174 a.a.        Molecular weight: 18873.67 Da        Isoelectric Point: 10.1333

>T37098 WP_199201390.1 NZ_AP023255:c11670-11149 [Mesorhizobium sp. 131-3-5]
MSLPPWGEEPVARHDRDSFDCGDAGLNEFLRVHARRNHERGASKTFLAVAKQDATILGFYTLSPAAAEFERVPEKFRKGI
GRYEIGGFRLARLAVARSIQGGGLGGQLLLAAALRCIRAAAEVGGTLMFIDAKNERVAAWYRSYGALGLEDRPLSLFLPL
ASFEAALRRGGRL

Download         Length: 522 bp

>T37098 NZ_AP023255:c11670-11149 [Mesorhizobium sp. 131-3-5]
ATGAGCCTGCCGCCCTGGGGCGAAGAGCCCGTCGCCCGGCACGACCGCGACAGTTTCGATTGCGGCGATGCCGGCCTCAA
TGAATTTCTTCGTGTCCATGCGCGTCGCAACCATGAGCGGGGCGCCTCGAAGACATTTCTTGCCGTGGCAAAACAAGACG
CAACGATTCTCGGTTTCTACACGCTGAGCCCCGCCGCTGCGGAGTTCGAGCGCGTGCCGGAGAAATTCCGCAAGGGCATC
GGCCGTTATGAGATCGGCGGCTTCCGGTTGGCGCGCCTCGCCGTGGCGCGGTCGATCCAAGGTGGGGGACTGGGCGGCCA
GTTGCTGCTTGCCGCGGCGTTGCGCTGCATTCGGGCAGCGGCCGAGGTTGGCGGAACACTGATGTTCATCGATGCCAAGA
ATGAGCGTGTGGCGGCATGGTATCGATCCTACGGCGCCCTGGGTCTGGAGGATCGTCCTTTGTCGTTATTCCTGCCGTTG
GCGTCATTCGAGGCCGCGCTTCGCCGTGGCGGGAGGCTTTGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10142.81 Da        Isoelectric Point: 10.7217

>AT37098 WP_128174838.1 NZ_AP023255:c11948-11667 [Mesorhizobium sp. 131-3-5]
MPRSAVPDSQRMSFRIKPADKAVILRATQLAGAAGITDFVLRTVLDASREIIKRNDRIVLSERDGLRVLEALENPPAPNE
KLIAAARALPADL

Download         Length: 282 bp

>AT37098 NZ_AP023255:c11948-11667 [Mesorhizobium sp. 131-3-5]
ATGCCCCGCTCCGCCGTCCCTGACAGCCAGCGCATGTCGTTTCGCATCAAGCCCGCCGACAAGGCGGTGATCCTGCGCGC
TACGCAGTTGGCGGGCGCCGCCGGGATAACGGATTTTGTCCTGCGCACCGTCCTCGACGCCTCCCGCGAGATTATCAAGC
GCAACGACCGAATCGTTTTGTCCGAACGCGACGGACTGCGCGTTCTGGAGGCGCTGGAGAACCCGCCCGCCCCCAACGAG
AAGCTTATCGCGGCGGCGCGGGCGTTGCCCGCCGATCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References