Detailed information of TA system TA037097

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/CC2985(antitoxin)
• Location: 3720397..3720947
• Replicon: chromosome
• Accession: NZ_AP023254
• Organism: Mesorhizobium sp. 131-3-5

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: JG747_RS18185
• Protein ID: WP_202359749.1
• Coordinates: 3720397..3720693 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: A0A6M7TQI6
• Locus tag: JG747_RS18190
• Protein ID: WP_027046965.1
• Coordinates: 3720693..3720947 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JG747_RS18150	3715710..3715889	+	180	WP_027046966.1	CbtB-domain containing protein	-
JG747_RS18155	3715905..3716711	+	807	WP_202359744.1	CbtA family protein	-
JG747_RS18160	3716704..3717219	+	516	WP_202359745.1	bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase	-
JG747_RS18165	3717221..3717850	+	630	WP_019858756.1	cob(I)yrinic acid a,c-diamide adenosyltransferase	-
JG747_RS18170	3717847..3718821	-	975	WP_202359746.1	cobalamin biosynthesis protein CobD	-
JG747_RS18175	3718820..3719866	+	1047	WP_202359747.1	threonine-phosphate decarboxylase	-
JG747_RS18180	3719863..3720372	+	510	WP_202359748.1	tyrosine phosphatase family protein	-
JG747_RS18185	3720397..3720693	-	297	WP_202359749.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
JG747_RS18190	3720693..3720947	-	255	WP_027046965.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
JG747_RS18195	3721129..3721932	-	804	WP_202359750.1	creatininase family protein	-
JG747_RS18200	3721987..3722370	-	384	WP_019858748.1	RidA family protein	-
JG747_RS18205	3722636..3723640	+	1005	WP_202359751.1	ABC transporter substrate-binding protein	-
JG747_RS18210	3723653..3724477	+	825	WP_202359752.1	ABC transporter ATP-binding protein	-
JG747_RS18215	3724464..3725312	+	849	WP_038647435.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-92)

Antitoxin

• Antitoxin ParD (6-63)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11310.98 Da
• Isoelectric Point: 6.6451

>T37097 WP_202359749.1 NZ_AP023254:c3720693-3720397 [Mesorhizobium sp. 131-3-5]
MGFRLSLAAEEDIIGIAEQRVRLFGGVQARQYHDELFAIFDLIAASPRMARERLELSPPMRIHPFKAHLVVYRIEVDGDV
FIVRVRHGHEDWANEGTR

Nucleotide

• Length: 297 bp

>T37097 NZ_AP023254:c3720693-3720397 [Mesorhizobium sp. 131-3-5]
ATGGGATTTCGCCTTTCTTTAGCCGCAGAAGAGGACATCATCGGTATTGCCGAGCAACGGGTGCGCCTGTTCGGTGGTGT
GCAGGCTAGACAGTATCATGACGAGTTGTTCGCGATCTTTGATCTGATCGCTGCCAGTCCCCGAATGGCACGGGAGCGGC
TTGAATTGTCGCCACCAATGCGTATCCATCCCTTCAAAGCCCATCTTGTCGTCTACCGGATAGAAGTCGACGGCGACGTG
TTCATTGTGCGGGTACGCCACGGGCACGAAGATTGGGCGAATGAAGGCACTCGATAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9347.38 Da
• Isoelectric Point: 6.3108

>AT37097 WP_027046965.1 NZ_AP023254:c3720947-3720693 [Mesorhizobium sp. 131-3-5]
MATMNVSLPDPMKDWVEAQTETGRYANASDYVRDLIRRDQERNDNIAAMQRFVDDGLKSGIGNRSRDALFTEAVKRAGKS
PGNG

Nucleotide

• Length: 255 bp

>AT37097 NZ_AP023254:c3720947-3720693 [Mesorhizobium sp. 131-3-5]
ATGGCAACAATGAACGTATCATTGCCTGATCCGATGAAGGATTGGGTTGAGGCGCAAACCGAAACGGGTCGCTACGCCAA
CGCGAGCGACTATGTGCGCGATTTGATCCGTCGGGATCAGGAGCGCAACGATAACATTGCCGCCATGCAACGCTTTGTCG
ATGACGGATTGAAGAGTGGCATCGGCAATCGATCCAGGGACGCGCTCTTTACTGAGGCAGTCAAGCGCGCTGGAAAGTCA
CCCGGCAACGGGTAA

Structures

Antitoxin

• AlphaFold DB: A0A6M7TQI6