Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT3-KacA/DUF1778(antitoxin)
Location 156752..157542 Replicon plasmid MesoLj131b2
Accession NZ_AP023250
Organism Mesorhizobium sp. 131-2-5

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag JG740_RS34885 Protein ID WP_199201789.1
Coordinates 157024..157542 (+) Length 173 a.a.

Antitoxin (Protein)


Gene name KacA Uniprot ID -
Locus tag JG740_RS34880 Protein ID WP_199201788.1
Coordinates 156752..157027 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG740_RS34855 152451..152696 + 246 WP_199201930.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
JG740_RS34860 152696..153106 + 411 WP_199201931.1 type II toxin-antitoxin system VapC family toxin -
JG740_RS34865 153103..154077 + 975 WP_199201932.1 tyrosine-type recombinase/integrase -
JG740_RS34870 154090..154206 + 117 Protein_136 very short patch repair endonuclease -
JG740_RS34875 154513..156600 + 2088 WP_199201933.1 hypothetical protein -
JG740_RS34880 156752..157027 + 276 WP_199201788.1 DUF1778 domain-containing protein Antitoxin
JG740_RS34885 157024..157542 + 519 WP_199201789.1 GNAT family N-acetyltransferase Toxin
JG740_RS34890 157648..159789 - 2142 WP_199201790.1 type IV secretory system conjugative DNA transfer family protein -
JG740_RS34895 159767..160825 - 1059 WP_199201791.1 P-type DNA transfer ATPase VirB11 -
JG740_RS34900 160785..162143 - 1359 WP_199201792.1 type IV secretion system protein VirB10 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..309689 309689


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(10-86)


Sequences

Toxin        


Download         Length: 173 a.a.        Molecular weight: 18432.15 Da        Isoelectric Point: 8.4584

>T37095 WP_199201789.1 NZ_AP023250:157024-157542 [Mesorhizobium sp. 131-2-5]
VSSIVWQEMPMGKQHDRAAFDCGDAELNTYLQRFARQNHESGGAKTFVAVTAEDLSHILGLYSLSPASMDYARTPAIAKR
GLGRYDVPVYRLGRIAVDRTIQGRGLGGGLLLAAGKRCMAVAQEVGGVALLIDAKGDQAARWYEGYGAIRLNDAPLSLVL
PFAAIARAIAEI

Download         Length: 519 bp

>T37095 NZ_AP023250:157024-157542 [Mesorhizobium sp. 131-2-5]
GTGAGTTCCATCGTCTGGCAGGAAATGCCGATGGGTAAACAGCATGACCGTGCCGCTTTCGACTGTGGCGACGCGGAGCT
CAATACCTACCTACAGCGCTTTGCGCGCCAAAACCACGAAAGCGGCGGCGCGAAAACCTTCGTGGCCGTGACGGCGGAAG
ATCTGTCGCACATCCTGGGGTTATATTCCCTCAGTCCCGCTTCCATGGACTATGCCCGCACTCCGGCGATCGCCAAGCGT
GGGCTCGGCCGCTACGACGTGCCGGTCTACCGTCTCGGTCGCATCGCGGTGGATCGTACGATACAAGGCCGCGGCCTCGG
TGGCGGTTTGCTACTCGCCGCCGGGAAGCGCTGCATGGCCGTCGCGCAGGAAGTTGGCGGCGTCGCCTTGCTTATCGACG
CCAAAGGTGACCAGGCAGCACGCTGGTATGAGGGCTACGGCGCGATCCGTCTTAATGATGCGCCGCTATCCCTGGTCCTG
CCTTTCGCCGCGATCGCCAGGGCGATAGCCGAGATATGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9815.20 Da        Isoelectric Point: 8.9951

>AT37095 WP_199201788.1 NZ_AP023250:156752-157027 [Mesorhizobium sp. 131-2-5]
MPRNVSDNGRIDFRIPPEAKAVIARAAALSNVGITEFVTRSALRDAQAAIERAEHLALSERDSLRVLDLLENPPAATDRL
IRAAKAGQTLA

Download         Length: 276 bp

>AT37095 NZ_AP023250:156752-157027 [Mesorhizobium sp. 131-2-5]
ATGCCCCGCAATGTCAGTGACAATGGCCGAATCGATTTCCGGATTCCGCCAGAAGCAAAAGCCGTGATCGCACGTGCAGC
GGCCTTGTCGAATGTCGGTATAACCGAGTTTGTCACGCGCTCAGCGCTGCGTGACGCTCAGGCCGCGATCGAACGCGCCG
AACATCTTGCGCTGTCTGAACGCGACAGCCTGCGTGTCCTCGACCTGCTCGAAAATCCGCCGGCGGCTACCGACCGTCTC
ATCCGTGCCGCCAAGGCCGGTCAGACCCTCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References