Detailed information of TA system TA037091

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 35217..36019
• Replicon: plasmid MesoLj131a2
• Accession: NZ_AP023248
• Organism: Mesorhizobium sp. 131-2-1

Toxin (Protein)

• Gene name: TacT3
• Uniprot ID: -
• Locus tag: JG743_RS32930
• Protein ID: WP_199200999.1
• Coordinates: 35217..35744 (-)
• Length: 176 a.a.

Antitoxin (Protein)

• Gene name: TacA3
• Uniprot ID: -
• Locus tag: JG743_RS32935
• Protein ID: WP_199201099.1
• Coordinates: 35741..36019 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JG743_RS32900	31137..31775	+	639	WP_199200993.1	toll/interleukin-1 receptor domain-containing protein	-
JG743_RS32905	31953..32507	+	555	WP_199200994.1	toll/interleukin-1 receptor domain-containing protein	-
JG743_RS32910	32519..32794	-	276	WP_199200995.1	hypothetical protein	-
JG743_RS32915	32716..32985	-	270	WP_202303229.1	hypothetical protein	-
JG743_RS32920	33222..33944	-	723	WP_199200997.1	SMC-Scp complex subunit ScpB	-
JG743_RS32925	33950..34972	-	1023	WP_199200998.1	DUF1403 family protein	-
JG743_RS32930	35217..35744	-	528	WP_199200999.1	GNAT family N-acetyltransferase	Toxin
JG743_RS32935	35741..36019	-	279	WP_199201099.1	DUF1778 domain-containing protein	Antitoxin
JG743_RS32940	36119..37228	+	1110	WP_199201000.1	site-specific integrase	-
JG743_RS32945	39093..40295	+	1203	WP_199201002.1	plasmid partitioning protein RepA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	htpB	1..285993	285993

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Vibrio phage ICP1, Orf50 (7-89)

Sequences

Toxin

Protein

• Length: 176 a.a.
• Molecular weight: 18897.77 Da
• Isoelectric Point: 7.8660

>T37091 WP_199200999.1 NZ_AP023248:c35744-35217 [Mesorhizobium sp. 131-2-1]
VSLPPWHEQAIARSHDRKAFDCGDVEMNAFLQRFARQGHEQNAVKTFCAVPDDAPEKILGFYSLAPASVEHHAVPPTMTK
GLARHDVPGFLLARLAVDKSVAGRGLGGQLLLAAALRCIRVTEEVGGVLMIIDAKSSRAASWYASYGAEPLNDRPMTLVL
PLKTFAESLKASGHL

Nucleotide

• Length: 528 bp

>T37091 NZ_AP023248:c35744-35217 [Mesorhizobium sp. 131-2-1]
GTGAGCCTTCCGCCCTGGCATGAGCAGGCGATCGCCCGGTCGCACGACCGGAAAGCCTTTGACTGTGGCGATGTCGAGAT
GAATGCCTTCTTGCAGCGCTTCGCGCGGCAAGGGCACGAGCAGAACGCGGTAAAGACGTTCTGTGCGGTACCCGACGATG
CACCGGAAAAAATCCTTGGCTTCTACAGTCTGGCTCCGGCCTCGGTCGAACATCACGCGGTTCCTCCCACGATGACGAAG
GGTCTGGCGCGACACGATGTGCCGGGCTTTCTGCTGGCGCGGCTTGCTGTCGACAAATCGGTGGCGGGCAGGGGGCTTGG
TGGCCAGCTTCTGCTCGCAGCCGCGCTGCGCTGCATCCGCGTTACTGAGGAAGTCGGCGGTGTGCTGATGATCATCGACG
CCAAAAGTAGTCGGGCCGCGAGCTGGTACGCGAGCTACGGCGCCGAGCCGCTGAACGATCGTCCAATGACGCTTGTCCTT
CCGCTCAAGACTTTTGCCGAATCCTTGAAAGCCAGCGGGCACCTCTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10104.72 Da
• Isoelectric Point: 10.9961

>AT37091 WP_199201099.1 NZ_AP023248:c36019-35741 [Mesorhizobium sp. 131-2-1]
MARAALDDTDRMNIRVKPEVKARLLRAAALRHTDLTSFVTQSALRAAETVIAEADTIKVSERDFGRILELLDNPPKPNAK
LRAAAAALPKTR

Nucleotide

• Length: 279 bp

>AT37091 NZ_AP023248:c36019-35741 [Mesorhizobium sp. 131-2-1]
ATGGCACGGGCAGCCCTTGATGATACTGATCGGATGAACATCCGGGTGAAGCCGGAGGTGAAGGCGCGCCTGTTGCGCGC
CGCAGCGCTTCGCCATACCGATCTCACCAGCTTCGTCACCCAGTCCGCGCTGCGCGCAGCCGAAACCGTAATCGCCGAAG
CTGACACCATAAAGGTATCAGAGCGGGATTTTGGCCGCATCCTAGAGCTTCTGGACAATCCTCCGAAGCCGAACGCCAAG
TTGCGTGCGGCGGCGGCCGCGCTTCCGAAGACCCGGTGA