Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 5170387..5170922 Replicon chromosome
Accession NZ_AP023246
Organism Mesorhizobium sp. 113-3-9

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MesoLj_RS25415 Protein ID WP_140767920.1
Coordinates 5170387..5170662 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MesoLj_RS25420 Protein ID WP_140767921.1
Coordinates 5170662..5170922 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MesoLj_RS25390 5165795..5166958 - 1164 WP_202322964.1 ABC transporter permease -
MesoLj_RS25395 5167014..5167925 - 912 WP_140767918.1 ABC transporter substrate-binding protein -
MesoLj_RS25400 5168100..5169317 - 1218 WP_202322965.1 MFS transporter -
MesoLj_RS25405 5169314..5169814 - 501 WP_056562492.1 transcription antitermination factor NusB -
MesoLj_RS25410 5169811..5170305 - 495 WP_202322966.1 6,7-dimethyl-8-ribityllumazine synthase -
MesoLj_RS25415 5170387..5170662 - 276 WP_140767920.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MesoLj_RS25420 5170662..5170922 - 261 WP_140767921.1 ribbon-helix-helix domain-containing protein Antitoxin
MesoLj_RS25425 5170998..5171615 - 618 WP_140767922.1 riboflavin synthase -
MesoLj_RS25430 5171626..5172756 - 1131 WP_202322967.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
MesoLj_RS25435 5172759..5173238 - 480 WP_056562515.1 transcriptional regulator NrdR -
MesoLj_RS25440 5173428..5174006 - 579 WP_202327451.1 hypothetical protein -
MesoLj_RS25445 5174106..5175419 - 1314 WP_015318249.1 serine hydroxymethyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-42)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10569.13 Da        Isoelectric Point: 7.0140

>T37089 WP_140767920.1 NZ_AP023246:c5170662-5170387 [Mesorhizobium sp. 113-3-9]
MELKWTNKALSDLVRLYDFLAPANGPAAARAVQALAAAPTRLLEYPRIGEKLEEFEPREVRRILVGSYEIRYEIQDTTIS
VLRLWHTREDR

Download         Length: 276 bp

>T37089 NZ_AP023246:c5170662-5170387 [Mesorhizobium sp. 113-3-9]
ATGGAGTTGAAATGGACCAACAAGGCTTTGTCCGACTTGGTCCGGCTCTATGATTTTCTCGCGCCGGCAAATGGCCCGGC
AGCCGCTCGCGCCGTGCAGGCGCTTGCTGCGGCACCGACACGGTTGCTCGAGTATCCGCGTATCGGCGAGAAACTGGAAG
AGTTCGAGCCACGAGAGGTGCGACGCATTTTGGTAGGCAGCTACGAAATTCGCTACGAAATACAGGACACGACAATTTCT
GTGTTGCGCCTGTGGCATACGCGAGAGGATCGATAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9628.08 Da        Isoelectric Point: 5.6994

>AT37089 WP_140767921.1 NZ_AP023246:c5170922-5170662 [Mesorhizobium sp. 113-3-9]
MDTKVITAHVPLPLAEKVDQLAARLERPRGWIVKQALSAWVDLEEERRRLTLEALADVDAGRVIDHQAVQAWAESLGTDK
PLPVPR

Download         Length: 261 bp

>AT37089 NZ_AP023246:c5170922-5170662 [Mesorhizobium sp. 113-3-9]
ATGGATACAAAAGTAATCACCGCTCACGTTCCGCTGCCGCTAGCCGAAAAGGTAGATCAGCTAGCTGCTCGCCTCGAGCG
CCCGCGCGGTTGGATCGTCAAACAGGCTCTTTCCGCGTGGGTGGATTTGGAGGAGGAGCGCCGGCGGCTCACGCTTGAAG
CATTGGCCGATGTGGATGCAGGACGGGTTATTGACCACCAGGCCGTTCAGGCGTGGGCTGAGAGTCTTGGCACCGACAAG
CCGCTGCCGGTGCCTCGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References