Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 1353398..1354053 Replicon chromosome
Accession NZ_AP023246
Organism Mesorhizobium sp. 113-3-9

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MesoLj_RS06505 Protein ID WP_202325480.1
Coordinates 1353398..1353799 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MesoLj_RS06510 Protein ID WP_113192000.1
Coordinates 1353799..1354053 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MesoLj_RS06485 1348831..1349865 - 1035 WP_202325476.1 aldo/keto reductase -
MesoLj_RS06490 1349922..1351103 - 1182 WP_202325477.1 MFS transporter -
MesoLj_RS06495 1351243..1352151 + 909 WP_202325478.1 LysR family transcriptional regulator -
MesoLj_RS06500 1352199..1353248 - 1050 WP_202325479.1 aldo/keto reductase -
MesoLj_RS06505 1353398..1353799 - 402 WP_202325480.1 type II toxin-antitoxin system VapC family toxin Toxin
MesoLj_RS06510 1353799..1354053 - 255 WP_113192000.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MesoLj_RS06515 1354134..1354796 - 663 WP_202325481.1 YggS family pyridoxal phosphate-dependent enzyme -
MesoLj_RS06520 1354953..1357577 + 2625 WP_202325482.1 leucine--tRNA ligase -
MesoLj_RS06525 1357564..1358142 + 579 WP_140776673.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-116)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-54)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14854.01 Da        Isoelectric Point: 4.9261

>T37087 WP_202325480.1 NZ_AP023246:c1353799-1353398 [Mesorhizobium sp. 113-3-9]
MYLLDTNIVSDVQRRLPKPTEWLASVDPTSVSLSVITLGEIERGIIKLRKVDSEKATRLDLWLRELRRDNADRILAVTED
VALTWGRITAGRTRGSADILIAATALVHDLILVTRNVADFDDTGVTVFNPWDA

Download         Length: 402 bp

>T37087 NZ_AP023246:c1353799-1353398 [Mesorhizobium sp. 113-3-9]
ATGTATCTGCTCGACACCAACATCGTTTCGGATGTGCAGAGGCGACTACCCAAGCCAACCGAATGGCTGGCTTCGGTGGA
TCCGACCTCGGTCAGCCTCAGCGTCATCACACTTGGAGAGATCGAGCGTGGGATCATCAAGCTACGCAAGGTCGACTCCG
AAAAGGCAACACGCCTCGATCTGTGGCTGCGGGAGCTTCGGCGCGACAATGCCGATCGTATTCTCGCCGTCACGGAAGAT
GTCGCGTTAACTTGGGGCCGCATCACCGCCGGCCGTACACGAGGCAGCGCCGATATCCTCATCGCGGCTACCGCTCTTGT
CCATGATCTCATTCTTGTGACGCGCAATGTTGCCGACTTCGACGATACAGGCGTGACGGTGTTCAATCCCTGGGACGCCT
AA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9608.75 Da        Isoelectric Point: 5.1409

>AT37087 WP_113192000.1 NZ_AP023246:c1354053-1353799 [Mesorhizobium sp. 113-3-9]
MNWHLQDAKNNFSKVVQRARSEGPQTVTLRGERAAVVLSAEDYDRLAGKKKSLAEYLLTGPVWDDDFAEEVNRRSETMIR
DVDL

Download         Length: 255 bp

>AT37087 NZ_AP023246:c1354053-1353799 [Mesorhizobium sp. 113-3-9]
ATGAACTGGCACCTTCAGGACGCAAAGAACAATTTCTCCAAGGTGGTTCAGCGTGCGCGCAGCGAGGGACCGCAGACGGT
GACGTTGCGCGGCGAGCGCGCCGCAGTGGTGCTTTCCGCCGAGGATTACGACCGCCTGGCCGGAAAGAAGAAGTCGTTGG
CCGAATATCTTTTGACTGGTCCGGTTTGGGACGATGATTTCGCCGAAGAGGTCAACCGCCGCTCGGAGACGATGATCCGG
GACGTCGATCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References