Detailed information of TA system TA037084

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yafQ-relB/YafQ-RelB
• Location: 5440891..5441423
• Replicon: chromosome
• Accession: NZ_AP023243
• Organism: Mesorhizobium sp. 113-3-3

Toxin (Protein)

• Gene name: yafQ
• Uniprot ID: -
• Locus tag: JG746_RS26715
• Protein ID: WP_202355440.1
• Coordinates: 5441151..5441423 (+)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: JG746_RS26710
• Protein ID: WP_202355439.1
• Coordinates: 5440891..5441148 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JG746_RS26700	5437726..5438691	+	966	WP_202355437.1	sugar-binding transcriptional regulator	-
JG746_RS26705	5438779..5440833	+	2055	WP_202355438.1	bifunctional aldolase/short-chain dehydrogenase	-
JG746_RS26710	5440891..5441148	+	258	WP_202355439.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
JG746_RS26715	5441151..5441423	+	273	WP_202355440.1	type II toxin-antitoxin system YafQ family toxin	Toxin
JG746_RS26720	5441507..5442559	-	1053	WP_202355441.1	substrate-binding domain-containing protein	-
JG746_RS26725	5442607..5443602	-	996	WP_096455690.1	ABC transporter permease	-
JG746_RS26730	5443684..5445195	-	1512	WP_202355442.1	sugar ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-88)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-84)

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10368.92 Da
• Isoelectric Point: 9.6565

>T37084 WP_202355440.1 NZ_AP023243:5441151-5441423 [Mesorhizobium sp. 113-3-3]
MPAPIHSGQFRRDVKRMEKRGKNLGKLRDLLGLLIAGHELPPTYKDHPLKGDWKGFRDAHIEPDWLLIYRVVGDELQLAR
TGSHSDLFNE

Nucleotide

• Length: 273 bp

>T37084 NZ_AP023243:5441151-5441423 [Mesorhizobium sp. 113-3-3]
ATGCCAGCGCCCATTCATTCCGGGCAATTTCGTCGGGATGTGAAGCGTATGGAAAAGCGTGGCAAGAACCTTGGGAAATT
GCGCGATCTGCTAGGCCTGCTGATCGCCGGGCATGAACTGCCGCCGACGTACAAAGATCATCCTCTGAAAGGCGACTGGA
AGGGCTTTCGAGACGCGCATATCGAACCGGACTGGCTCCTGATCTACCGCGTTGTCGGCGATGAATTGCAGCTTGCCCGT
ACCGGTTCACATTCCGACCTGTTCAACGAGTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9089.59 Da
• Isoelectric Point: 9.9482

>AT37084 WP_202355439.1 NZ_AP023243:5440891-5441148 [Mesorhizobium sp. 113-3-3]
MATDAVVRARIDAATKDQATEALAAMGLSVSDAIRLLLVRVAADKEFPFPVKVPNATTRKAMAELEKGKGKRFASADELF
KDLGL

Nucleotide

• Length: 258 bp

>AT37084 NZ_AP023243:5440891-5441148 [Mesorhizobium sp. 113-3-3]
ATGGCTACAGATGCAGTGGTCCGCGCTCGGATCGACGCCGCGACGAAGGATCAGGCAACGGAAGCTTTGGCGGCCATGGG
CTTGTCGGTCTCCGATGCCATTCGCCTGCTCCTGGTGCGCGTGGCCGCCGACAAGGAATTTCCTTTCCCGGTGAAAGTGC
CTAACGCAACCACGCGAAAGGCCATGGCCGAATTGGAAAAAGGCAAAGGCAAGCGCTTCGCCTCGGCTGATGAATTGTTC
AAGGATCTGGGGCTCTAG