Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 530487..531172 Replicon chromosome
Accession NZ_AP023242
Organism Mesorhizobium sp. 113-1-2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JN279_RS02420 Protein ID WP_096452671.1
Coordinates 530750..531172 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JN279_RS02415 Protein ID WP_096452673.1
Coordinates 530487..530753 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN279_RS02390 526523..527599 + 1077 WP_202351881.1 ABC transporter permease -
JN279_RS02395 527602..528369 + 768 WP_096452679.1 sugar ABC transporter ATP-binding protein -
JN279_RS02400 528483..529478 + 996 WP_096452677.1 inositol 2-dehydrogenase -
JN279_RS02405 529509..530303 + 795 WP_202351882.1 SDR family oxidoreductase -
JN279_RS02410 530267..530410 - 144 WP_202351883.1 hypothetical protein -
JN279_RS02415 530487..530753 + 267 WP_096452673.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JN279_RS02420 530750..531172 + 423 WP_096452671.1 type II toxin-antitoxin system VapC family toxin Toxin
JN279_RS02425 531188..531478 + 291 WP_202351884.1 hypothetical protein -
JN279_RS02430 531685..532776 + 1092 WP_096452668.1 3-deoxy-7-phosphoheptulonate synthase -
JN279_RS02435 532825..533460 - 636 WP_096452666.1 LysE family translocator -
JN279_RS02440 533589..534284 + 696 WP_096452664.1 YafY family transcriptional regulator -
JN279_RS02445 534297..535406 - 1110 WP_202351885.1 Gfo/Idh/MocA family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-70)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15602.84 Da        Isoelectric Point: 4.5606

>T37073 WP_096452671.1 NZ_AP023242:530750-531172 [Mesorhizobium sp. 113-1-2]
VRLLLDTNVLSEVTRPAPDASVLDWLDGLDEDRSFISVISIAEIRRGVALMDEGRKREALAEWLARDLPQRFEQRVLPVD
EPVALAWGDLMGLAKRRGRGLSSMDGLIAATAIARQLTLATRNTRDFEGFGIELFDPWTA

Download         Length: 423 bp

>T37073 NZ_AP023242:530750-531172 [Mesorhizobium sp. 113-1-2]
GTGAGGCTGCTGCTCGATACGAATGTCCTGTCCGAGGTGACAAGGCCGGCGCCGGACGCAAGCGTTCTGGACTGGCTGGA
CGGGCTTGATGAGGACCGCTCATTCATCAGCGTCATATCGATCGCCGAGATCCGGCGCGGCGTCGCCCTGATGGATGAGG
GCCGGAAACGCGAGGCACTCGCCGAATGGCTCGCTCGGGACCTGCCGCAGCGCTTCGAGCAAAGGGTTTTGCCGGTGGAC
GAACCGGTTGCCTTGGCCTGGGGCGACCTGATGGGCCTTGCCAAGCGCCGTGGGCGCGGCCTGTCATCGATGGACGGCCT
GATCGCAGCCACGGCGATTGCGCGGCAGCTCACCTTGGCAACGCGCAATACCAGGGATTTCGAAGGCTTCGGAATAGAAC
TCTTCGATCCCTGGACGGCATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9796.10 Da        Isoelectric Point: 8.7461

>AT37073 WP_096452673.1 NZ_AP023242:530487-530753 [Mesorhizobium sp. 113-1-2]
MRPETKEDTNWTVAGAKARLSEVIERAQSSPQTITKNGKPSVVVVSAEEWQRKTVRKGTLAQFLLGSPLRGADLDLERQP
DEPRDLPL

Download         Length: 267 bp

>AT37073 NZ_AP023242:530487-530753 [Mesorhizobium sp. 113-1-2]
ATGCGTCCTGAGACCAAAGAGGATACCAACTGGACGGTCGCCGGAGCAAAGGCCCGGCTCTCGGAGGTTATCGAGCGCGC
GCAGTCGTCGCCGCAGACGATCACCAAGAACGGCAAGCCAAGCGTGGTTGTCGTCTCGGCCGAGGAATGGCAGCGGAAGA
CCGTGCGCAAGGGTACGCTTGCGCAGTTCCTGCTGGGGTCACCGCTGCGCGGCGCCGATCTCGACCTTGAACGTCAGCCC
GACGAGCCGCGTGACCTGCCGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References