Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2237146..2237417 Replicon chromosome
Accession NZ_AP023235
Organism Escherichia coli strain YJ6

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2237276..2237379 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2237146..2237417 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HXS64_RS10705 2233701..2234363 - 663 WP_047603977.1 exodeoxyribonuclease X -
HXS64_RS10710 2234387..2235043 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
HXS64_RS10715 2235145..2235375 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HXS64_RS10720 2235514..2235888 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HXS64_RS10725 2235892..2236764 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
HXS64_RS10730 2236777..2237118 + 342 WP_000976472.1 YebY family protein -
- 2237146..2237417 - 272 - - Antitoxin
- 2237276..2237379 + 104 - - Toxin
HXS64_RS10735 2237514..2238008 + 495 Protein_2079 protein-serine/threonine phosphatase -
HXS64_RS10740 2238063..2238761 + 699 Protein_2080 IS1 family transposase -
HXS64_RS10745 2238778..2238948 + 171 Protein_2081 serine/threonine-protein phosphatase -
HXS64_RS10750 2238949..2239140 - 192 WP_001338167.1 YebW family protein -
HXS64_RS10755 2239245..2239481 - 237 WP_001338166.1 DUF1480 family protein -
HXS64_RS10760 2239599..2241038 - 1440 WP_001397399.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2215127..2238761 23634


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T37024 NZ_AP023235:2237276-2237379 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT37024 NZ_AP023235:c2237417-2237146 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References