Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4249109..4249380 Replicon chromosome
Accession NZ_AP023230
Organism Escherichia coli strain YJ4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4249239..4249342 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4249109..4249380 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HXS62_RS20265 4245664..4246326 - 663 WP_000944256.1 exodeoxyribonuclease X -
HXS62_RS20270 4246350..4247006 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
HXS62_RS20275 4247108..4247338 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HXS62_RS20280 4247477..4247851 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HXS62_RS20285 4247855..4248727 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
HXS62_RS20290 4248740..4249081 + 342 WP_000976476.1 YebY family protein -
- 4249109..4249380 - 272 - - Antitoxin
- 4249239..4249342 + 104 - - Toxin
HXS62_RS20295 4249477..4250133 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
HXS62_RS20300 4250134..4250325 - 192 WP_000457842.1 YebW family protein -
HXS62_RS20305 4250430..4250666 - 237 WP_001295499.1 DUF1480 family protein -
HXS62_RS20310 4250784..4252223 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T37001 NZ_AP023230:4249239-4249342 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT37001 NZ_AP023230:c4249380-4249109 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References