Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1771942..1772213 Replicon chromosome
Accession NZ_AP023219
Organism Escherichia coli strain M505

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1771980..1772083 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1771942..1772213 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EPG46_RS08490 1769099..1770538 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EPG46_RS08495 1770656..1770892 + 237 WP_001295499.1 DUF1480 family protein -
EPG46_RS08500 1770997..1771188 + 192 WP_000457842.1 YebW family protein -
EPG46_RS08505 1771189..1771845 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1771942..1772213 + 272 - - Antitoxin
- 1771980..1772083 - 104 - - Toxin
EPG46_RS08510 1772241..1772582 - 342 WP_000976476.1 YebY family protein -
EPG46_RS08515 1772595..1773467 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
EPG46_RS08520 1773471..1773845 - 375 WP_000168747.1 CopC domain-containing protein YobA -
EPG46_RS08525 1773984..1774214 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EPG46_RS08530 1774316..1774972 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
EPG46_RS08535 1774996..1775658 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T36893 NZ_AP023219:c1772083-1771980 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT36893 NZ_AP023219:1771942-1772213 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References