Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2569783..2570054 Replicon chromosome
Accession NZ_AP023205
Organism Escherichia coli strain TUM18781

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2569913..2570016 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2569783..2570054 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUV20_RS12195 2566338..2567000 - 663 WP_000944256.1 exodeoxyribonuclease X -
HUV20_RS12200 2567024..2567680 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
HUV20_RS12205 2567782..2568012 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HUV20_RS12210 2568151..2568525 + 375 WP_000204700.1 CopC domain-containing protein YobA -
HUV20_RS12215 2568529..2569401 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
HUV20_RS12220 2569414..2569755 + 342 WP_000976472.1 YebY family protein -
- 2569783..2570054 - 272 - - Antitoxin
- 2569913..2570016 + 104 - - Toxin
HUV20_RS12225 2570151..2570807 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
HUV20_RS12230 2570808..2570999 - 192 WP_001296140.1 YebW family protein -
HUV20_RS12235 2571104..2571340 - 237 WP_001295499.1 DUF1480 family protein -
HUV20_RS12240 2571458..2572897 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T36867 NZ_AP023205:2569913-2570016 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT36867 NZ_AP023205:c2570054-2569783 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References