Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1999025..1999296 Replicon chromosome
Accession NZ_AP023190
Organism Escherichia coli strain TUM18530

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1999155..1999258 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1999025..1999296 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUV24_RS09415 1995580..1996242 - 663 WP_000944256.1 exodeoxyribonuclease X -
HUV24_RS09420 1996266..1996922 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
HUV24_RS09425 1997024..1997254 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HUV24_RS09430 1997393..1997767 + 375 WP_021556896.1 CopC domain-containing protein YobA -
HUV24_RS09435 1997771..1998643 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
HUV24_RS09440 1998656..1998997 + 342 WP_000976472.1 YebY family protein -
- 1999025..1999296 - 272 - - Antitoxin
- 1999155..1999258 + 104 - - Toxin
HUV24_RS09445 1999393..2000049 + 657 WP_021556895.1 protein-serine/threonine phosphatase -
HUV24_RS09450 2000050..2000241 - 192 WP_001313035.1 YebW family protein -
HUV24_RS09455 2000346..2000582 - 237 WP_001295499.1 DUF1480 family protein -
HUV24_RS09460 2000700..2002139 - 1440 WP_024227172.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T36799 NZ_AP023190:1999155-1999258 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT36799 NZ_AP023190:c1999296-1999025 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References