Detailed information of TA system TA036792

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Xre(antitoxin)
• Location: 4955835..4956994
• Replicon: chromosome
• Accession: NZ_AP023189
• Organism: Pseudomonas sp. TUM18999

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: HSX14_RS22515
• Protein ID: WP_111264583.1
• Coordinates: 4955835..4956587 (-)
• Length: 251 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: HSX14_RS22520
• Protein ID: WP_111264584.1
• Coordinates: 4956623..4956994 (-)
• Length: 124 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HSX14_RS22495	4951545..4952429	+	885	WP_173171944.1	metal-dependent hydrolase	-
HSX14_RS22500	4952500..4953975	-	1476	WP_173171942.1	DNA recombination protein RmuC	-
HSX14_RS22505	4954028..4954435	-	408	WP_173171940.1	SEL1-like repeat protein	-
HSX14_RS22510	4954783..4955838	-	1056	WP_173171938.1	AraC family transcriptional regulator	-
HSX14_RS22515	4955835..4956587	-	753	WP_111264583.1	RES family NAD+ phosphorylase	Toxin
HSX14_RS22520	4956623..4956994	-	372	WP_111264584.1	DUF2384 domain-containing protein	Antitoxin
HSX14_RS22525	4957118..4957600	+	483	WP_173171936.1	transcription elongation factor GreAB	-
HSX14_RS22530	4957652..4958047	+	396	WP_173171933.1	hypothetical protein	-
HSX14_RS22535	4958450..4958902	-	453	WP_173171931.1	S24 family peptidase	-
HSX14_RS22540	4959004..4960602	-	1599	WP_173171929.1	M28 family peptidase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (58-206)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (72-121)

Sequences

Toxin

Protein

• Length: 251 a.a.
• Molecular weight: 28141.12 Da
• Isoelectric Point: 7.1064

>T36792 WP_111264583.1 NZ_AP023189:c4956587-4955835 [Pseudomonas sp. TUM18999]
MDIWTTCQGPQHIGPLRGRLVRLVESQEQVATLQLVDNLAEQALLEELIETSKPPLPRSAEPLHYLLKTPFRYPPLRWGS
RFGTVHEPSLFYAASRLETAMAEGAFYRFVLWSGMAVPPPSGRILSEHSSFEARFQVERGVQLQSPPFDRHAQALADPVD
YRASQALGAAMRAAGVEAFEYRSARCPLQGTNIALFTPEAFTERRPRNLTPWLCETTAEYVAFKHAQAPDTPRLFRMTQF
LIDGHLPQPA

Nucleotide

• Length: 753 bp

>T36792 NZ_AP023189:c4956587-4955835 [Pseudomonas sp. TUM18999]
ATGGATATCTGGACGACCTGCCAGGGCCCGCAACACATCGGGCCCCTGCGTGGCCGCCTGGTGCGCCTGGTGGAGAGCCA
GGAGCAGGTGGCGACCCTGCAGCTGGTGGACAACCTCGCCGAACAGGCGTTGCTGGAGGAACTCATCGAGACCAGCAAGC
CGCCGTTGCCCAGGAGCGCCGAGCCGCTGCACTACCTGCTCAAGACCCCGTTCCGCTACCCGCCGCTGCGCTGGGGGTCG
CGCTTCGGCACCGTCCACGAGCCGAGCCTGTTCTACGCCGCCTCGCGCCTGGAGACCGCCATGGCCGAGGGGGCGTTCTA
CCGCTTCGTCCTGTGGAGCGGCATGGCCGTGCCGCCCCCCAGCGGGCGCATCCTGTCCGAGCATTCCTCCTTCGAGGCGC
GTTTCCAGGTGGAGCGTGGCGTGCAACTGCAATCGCCACCGTTCGATCGTCACGCTCAGGCACTGGCCGACCCGGTGGAC
TACCGCGCCAGCCAGGCGCTCGGCGCGGCCATGCGTGCCGCAGGCGTGGAGGCCTTCGAGTACCGCTCCGCGCGCTGCCC
GCTGCAGGGCACCAATATCGCCCTGTTCACCCCCGAGGCCTTCACCGAGCGGCGACCACGCAACCTCACGCCCTGGCTCT
GCGAGACCACCGCCGAGTACGTCGCCTTCAAGCATGCCCAGGCACCGGATACGCCGCGCCTGTTCCGCATGACGCAGTTC
CTGATCGACGGCCACCTGCCACAGCCGGCATGA

Antitoxin

Protein

• Length: 124 a.a.
• Molecular weight: 13570.78 Da
• Isoelectric Point: 10.2920

>AT36792 WP_111264584.1 NZ_AP023189:c4956994-4956623 [Pseudomonas sp. TUM18999]
MSALSRPTLDPDAVLAKALLNTREQLGLTQQQLADIVGVHRTAITRWADSGGIRPQSKTGELALLLIRAYRALFALFGGN
LDDMRHFLRTENRHLGAVPLELMGQVQGLVRVVEYLDAIRGKI

Nucleotide

• Length: 372 bp

>AT36792 NZ_AP023189:c4956994-4956623 [Pseudomonas sp. TUM18999]
ATGAGCGCCCTCAGCCGTCCCACTCTCGATCCCGATGCCGTCCTGGCCAAGGCCCTGCTCAATACCCGCGAGCAACTCGG
GCTGACCCAGCAGCAACTGGCCGACATCGTCGGTGTGCACCGCACCGCCATCACCCGCTGGGCGGACAGCGGCGGCATCC
GTCCGCAGAGCAAGACCGGCGAGCTCGCGCTGCTGCTGATCCGCGCCTACCGCGCATTGTTCGCCCTGTTCGGCGGCAAC
CTCGACGACATGCGCCACTTCCTGCGCACCGAGAACCGCCACCTGGGCGCCGTTCCCCTCGAACTGATGGGCCAGGTGCA
GGGTCTGGTGAGGGTGGTGGAGTACCTGGACGCCATACGCGGCAAGATCTGA