Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 4943039..4944447 Replicon chromosome
Accession NZ_AP023189
Organism Pseudomonas sp. TUM18999

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag HSX14_RS22470 Protein ID WP_173171955.1
Coordinates 4943878..4944447 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag HSX14_RS22465 Protein ID WP_173171957.1
Coordinates 4943039..4943881 (-) Length 281 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HSX14_RS22440 4938458..4939405 + 948 WP_173171968.1 bile acid:sodium symporter family protein -
HSX14_RS22445 4939553..4939867 + 315 WP_173171966.1 quaternary ammonium compound efflux SMR transporter SugE -
HSX14_RS22450 4939931..4941805 - 1875 WP_173171964.1 MFS transporter -
HSX14_RS22455 4941958..4942287 - 330 WP_173171961.1 AzlD domain-containing protein -
HSX14_RS22460 4942287..4943000 - 714 WP_173171959.1 AzlC family ABC transporter permease -
HSX14_RS22465 4943039..4943881 - 843 WP_173171957.1 AraC family transcriptional regulator Antitoxin
HSX14_RS22470 4943878..4944447 - 570 WP_173171955.1 GNAT family N-acetyltransferase Toxin
HSX14_RS22475 4944699..4948175 + 3477 WP_173171953.1 PAS-domain containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

AraC-type arabinose-binding/dimerisation domain

(17-149)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21263.22 Da        Isoelectric Point: 6.8864

>T36791 WP_173171955.1 NZ_AP023189:c4944447-4943878 [Pseudomonas sp. TUM18999]
MFNPQPVILQRGALRLEPLGEADITELSALAEANRDELVYMSGPLRPDWYRQGLAEQREGQAVVFAIRLGDRLVGTSRFA
DFMPALPAVEIGWTWLARSEHASGLNASIKYLMLRHAFEEWQVVRVQLKTAGSNLRSQKAIEKLGAQREGVLRNHRRLAD
GRLDDSVLYSITDHEWPAVKQALEASFGQ

Download         Length: 570 bp

>T36791 NZ_AP023189:c4944447-4943878 [Pseudomonas sp. TUM18999]
ATGTTCAATCCGCAACCGGTGATCCTGCAGCGCGGCGCCTTGCGCCTCGAGCCGCTGGGGGAGGCCGACATCACCGAACT
CTCGGCACTGGCCGAGGCCAATCGCGATGAGCTGGTCTACATGAGCGGCCCGCTGCGCCCGGACTGGTACCGCCAGGGCC
TGGCCGAGCAGCGTGAAGGCCAGGCCGTGGTGTTCGCCATCCGCCTGGGCGACCGCCTGGTGGGTACCAGCCGCTTCGCC
GATTTCATGCCCGCGCTGCCGGCCGTGGAGATCGGCTGGACCTGGCTGGCCCGCAGCGAGCATGCCAGCGGCCTCAATGC
CTCGATCAAGTACCTGATGCTGCGCCATGCCTTCGAGGAGTGGCAGGTGGTGCGCGTGCAACTGAAGACCGCCGGCAGCA
ACCTGCGCTCGCAGAAGGCCATCGAGAAACTCGGTGCCCAGCGCGAAGGCGTCCTGCGCAACCATCGCCGCCTGGCGGAC
GGGCGCCTCGACGACAGCGTGCTCTACAGCATCACCGACCATGAGTGGCCGGCCGTGAAGCAGGCCCTGGAAGCCTCATT
CGGCCAATGA

Antitoxin


Download         Length: 281 a.a.        Molecular weight: 31234.58 Da        Isoelectric Point: 8.7189

>AT36791 WP_173171957.1 NZ_AP023189:c4943881-4943039 [Pseudomonas sp. TUM18999]
MSTGGERTRFWQASALGGVELLHARYIEQRFSPHVHEGYVFTVLESGAQRFRHRGSDHLAAVGSMVLINPDELHTGSKAH
EEGWRYRGFYPDLHRVTEVLDELEIATGGLPTFADSVLHDPEVTRRFLDLHRLLERNASALEQQVAWREAILLLFSRHAC
IGAPRPAGQEPHAVALAREMLAARLASPPSLEELAALVGLSPFHFARVFRRATGLPPHAWLKQRRLEQARALLREGCAPL
PVAMQLGFADQSHLTRQFKQAYGVGPGEYRSACARSFKTG

Download         Length: 843 bp

>AT36791 NZ_AP023189:c4943881-4943039 [Pseudomonas sp. TUM18999]
ATGAGCACGGGTGGCGAGCGGACGCGCTTCTGGCAGGCCAGCGCGCTGGGCGGGGTCGAACTCCTGCACGCGCGCTACAT
CGAGCAGCGTTTCTCGCCCCATGTGCACGAGGGCTACGTCTTCACCGTCCTCGAATCCGGCGCCCAGCGCTTCCGCCACC
GCGGCAGCGACCACCTGGCTGCCGTCGGCAGCATGGTGCTGATCAACCCGGACGAGCTGCATACGGGCTCCAAGGCCCAC
GAGGAAGGTTGGCGCTACCGCGGCTTCTACCCCGACCTGCACCGGGTGACCGAGGTGCTGGACGAACTGGAGATCGCCAC
CGGCGGCCTGCCCACCTTCGCCGACAGCGTGCTGCATGACCCCGAGGTGACCCGCCGCTTCCTCGACCTGCACCGCCTGC
TGGAGCGCAACGCCTCCGCCCTGGAGCAGCAGGTGGCCTGGCGCGAGGCGATCCTGCTGCTGTTCAGCCGCCACGCGTGC
ATTGGTGCGCCCCGGCCGGCAGGGCAGGAGCCCCATGCCGTGGCGCTGGCCCGCGAGATGCTGGCGGCGCGCCTGGCATC
GCCACCCTCCCTGGAGGAGCTGGCTGCCCTGGTGGGGCTTTCGCCGTTCCATTTCGCCCGGGTGTTCCGCCGGGCCACCG
GGTTGCCACCCCACGCCTGGCTGAAGCAGCGTCGCCTGGAGCAGGCTCGGGCGCTGCTGCGCGAAGGCTGCGCGCCGCTG
CCGGTGGCGATGCAGCTGGGCTTCGCCGACCAGAGCCACCTGACCCGCCAGTTCAAGCAGGCTTACGGCGTCGGTCCGGG
TGAGTACCGCAGCGCCTGCGCAAGATCGTTCAAGACCGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References