Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2343744..2344260 Replicon chromosome
Accession NZ_AP023189
Organism Pseudomonas sp. TUM18999

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HSX14_RS10780 Protein ID WP_125861722.1
Coordinates 2343979..2344260 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HSX14_RS10775 Protein ID WP_132444928.1
Coordinates 2343744..2343989 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HSX14_RS10755 2338882..2340132 + 1251 WP_069900667.1 cytochrome P450 -
HSX14_RS10760 2340290..2340874 - 585 WP_041013396.1 hypothetical protein -
HSX14_RS10765 2340892..2342082 - 1191 WP_017246246.1 thioredoxin family protein -
HSX14_RS10770 2342861..2343559 + 699 WP_173178439.1 inovirus Gp2 family protein -
HSX14_RS10775 2343744..2343989 + 246 WP_132444928.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HSX14_RS10780 2343979..2344260 + 282 WP_125861722.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HSX14_RS10785 2344330..2344503 - 174 WP_165362587.1 hypothetical protein -
HSX14_RS10790 2344514..2345011 - 498 WP_034019467.1 DNA repair protein RadC -
HSX14_RS10795 2344983..2345933 - 951 WP_173178440.1 hydrolase or metal-binding protein -
HSX14_RS10800 2346024..2347028 - 1005 WP_173178441.1 YqaJ viral recombinase family protein -
HSX14_RS10805 2347107..2348075 - 969 WP_173178442.1 DUF932 domain-containing protein -
HSX14_RS10810 2348173..2348445 - 273 WP_173178455.1 hypothetical protein -
HSX14_RS10815 2348926..2349258 + 333 WP_173178443.1 AlpA family phage regulatory protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2342861..2370912 28051


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10781.67 Da        Isoelectric Point: 10.7574

>T36787 WP_125861722.1 NZ_AP023189:2343979-2344260 [Pseudomonas sp. TUM18999]
MTYKLEFLPSALKEWEKLGHTVREQAKKKLRERLEAPKVQADALRDLPGHYKIKLRTAGYRLVYRVEDDRVVVMVVAVGK
RERSAAYKAAGKR

Download         Length: 282 bp

>T36787 NZ_AP023189:2343979-2344260 [Pseudomonas sp. TUM18999]
ATGACCTATAAGCTCGAGTTCCTGCCCTCGGCGCTGAAGGAATGGGAGAAGCTGGGTCATACGGTGCGTGAGCAGGCAAA
GAAAAAACTGCGTGAGCGGCTGGAAGCACCAAAGGTTCAGGCTGATGCCCTCAGGGATCTGCCTGGGCACTACAAGATCA
AGCTCCGAACAGCAGGCTATCGATTGGTCTATCGGGTCGAAGATGATCGTGTGGTTGTGATGGTGGTCGCAGTGGGCAAG
CGTGAACGAAGTGCAGCTTACAAGGCAGCAGGTAAGCGTTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8668.00 Da        Isoelectric Point: 4.1630

>AT36787 WP_132444928.1 NZ_AP023189:2343744-2343989 [Pseudomonas sp. TUM18999]
MQSVLADVAVSVSELKKNPTGVMAGAGGMPVAVLNHNRVMGYMVPAELYEQMLERLDDLDLIDVVNARSGEKGVPVNLDD
L

Download         Length: 246 bp

>AT36787 NZ_AP023189:2343744-2343989 [Pseudomonas sp. TUM18999]
ATGCAGAGTGTTTTGGCTGACGTTGCCGTGAGCGTTTCTGAGCTGAAGAAAAACCCCACCGGTGTCATGGCTGGTGCTGG
TGGCATGCCGGTCGCCGTTCTCAATCATAACCGCGTGATGGGGTACATGGTGCCAGCCGAGCTGTACGAGCAGATGCTGG
AGCGTCTGGACGATCTGGATCTGATCGATGTCGTTAATGCACGCTCTGGTGAGAAGGGTGTGCCGGTGAACCTGGATGAC
CTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References