Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 793041..793579 Replicon plasmid PPGU19_p3
Accession NZ_AP023183
Organism Paraburkholderia sp. PGU19

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag H1204_RS50760 Protein ID WP_180736646.1
Coordinates 793280..793579 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag H1204_RS50755 Protein ID WP_180737010.1
Coordinates 793041..793283 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H1204_RS50730 788654..789643 + 990 WP_180736643.1 ParB/RepB/Spo0J family partition protein -
H1204_RS50735 790803..790982 + 180 WP_180737009.1 type II toxin-antitoxin system ParD family antitoxin -
H1204_RS50740 791456..791593 + 138 WP_180736644.1 hypothetical protein -
H1204_RS50745 791968..792198 + 231 WP_091788763.1 CopG family transcriptional regulator -
H1204_RS50750 792198..792629 + 432 WP_180736645.1 PIN domain-containing protein -
H1204_RS50755 793041..793283 + 243 WP_180737010.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
H1204_RS50760 793280..793579 + 300 WP_180736646.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H1204_RS50765 793910..794662 + 753 WP_180736647.1 hypothetical protein -
H1204_RS50770 794647..795339 + 693 WP_180736648.1 hypothetical protein -
H1204_RS50775 796238..797863 + 1626 WP_180736649.1 tannase/feruloyl esterase family alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB / htpB 1..852821 852821


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11364.82 Da        Isoelectric Point: 5.0829

>T36765 WP_180736646.1 NZ_AP023183:793280-793579 [Paraburkholderia sp. PGU19]
VKQFVLSPAAELDLDDIWDYSAENWGIRQAERYIRMIQDTIIGLTDGTQPSQAASRVRPGYRSVLVGTHILFFKETDSLV
DVIRILHQRMDPSEHLSEH

Download         Length: 300 bp

>T36765 NZ_AP023183:793280-793579 [Paraburkholderia sp. PGU19]
GTGAAGCAGTTTGTTCTTTCGCCGGCGGCCGAACTGGATCTCGATGATATCTGGGACTATTCGGCAGAGAACTGGGGGAT
CCGACAGGCAGAGCGCTATATCCGCATGATTCAGGACACGATCATTGGATTGACTGACGGCACACAGCCGAGTCAGGCCG
CCTCCCGCGTTCGACCGGGTTACCGCAGCGTGCTGGTCGGCACGCACATTCTGTTTTTCAAGGAGACCGATAGCCTGGTC
GACGTCATCCGGATTCTGCACCAGCGGATGGATCCCTCTGAGCACCTGAGCGAGCACTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8970.01 Da        Isoelectric Point: 7.0156

>AT36765 WP_180737010.1 NZ_AP023183:793041-793283 [Paraburkholderia sp. PGU19]
MGKNTSVSLGDHFAEFVEDRVRAGRYNTASDVVRAGLRLLEEQEAKLDALRVELEKGERSGPSRPFDFDAFLARKRQSAT

Download         Length: 243 bp

>AT36765 NZ_AP023183:793041-793283 [Paraburkholderia sp. PGU19]
ATGGGCAAGAATACCTCCGTTTCGCTCGGCGACCACTTTGCCGAATTTGTCGAAGACCGCGTGCGGGCCGGGCGCTACAA
CACGGCGAGCGACGTGGTTCGGGCCGGCCTGCGCTTGCTGGAGGAACAGGAAGCAAAACTCGATGCCCTGCGCGTCGAAC
TGGAGAAGGGCGAGCGTTCGGGTCCGTCCAGGCCGTTTGACTTCGATGCGTTTCTCGCACGCAAGAGGCAGTCCGCGACG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References