Detailed information of TA system TA036763

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): slvAT/RES(toxin)
• Location: 394337..395232
• Replicon: plasmid PPGU19_p1
• Accession: NZ_AP023181
• Organism: Paraburkholderia sp. PGU19

Toxin (Protein)

• Gene name: slvT
• Uniprot ID: -
• Locus tag: H1204_RS31665
• Protein ID: WP_180734489.1
• Coordinates: 394337..394864 (-)
• Length: 176 a.a.

Antitoxin (Protein)

• Gene name: slvA
• Uniprot ID: -
• Locus tag: H1204_RS31670
• Protein ID: WP_180734490.1
• Coordinates: 394861..395232 (-)
• Length: 124 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H1204_RS31650	389392..390411	+	1020	WP_180734487.1	Ldh family oxidoreductase	-
H1204_RS31655	390624..393115	-	2492	Protein_361	S8 family peptidase	-
H1204_RS31660	393090..394118	-	1029	WP_180734488.1	ATP-binding protein	-
H1204_RS31665	394337..394864	-	528	WP_180734489.1	RES family NAD+ phosphorylase	Toxin
H1204_RS31670	394861..395232	-	372	WP_180734490.1	DNA-binding protein	Antitoxin
H1204_RS31675	395640..396149	-	510	WP_180734491.1	hypothetical protein	-
H1204_RS31680	396881..398326	+	1446	WP_180734492.1	IS1182 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	clpV1 / hcp1 / hsiC1/vipB / hsiB1/vipA / adeG / acrB	1..2380791	2380791
	-	flank	IS/Tn	-	-	396881..398326	1445

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (12-169)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 176 a.a.
• Molecular weight: 20028.57 Da
• Isoelectric Point: 6.1381

>T36763 WP_180734489.1 NZ_AP023181:c394864-394337 [Paraburkholderia sp. PGU19]
MILTHLPAGTMLYRAHAPRWASRPASGAGAAAKGGRFNREGIEALYLSLEELTALREYQQTSPFLPPCTVCSYTVALRNL
VDLRQLHRDPLWDDLWHDWREDWRHLKFELHIEPPTWVLSDMVREQGFTGIVFPSQTHERGTNVVVFTDRLGDGNSIEVN
DPDGQLPRDQASWPR

Nucleotide

• Length: 528 bp

>T36763 NZ_AP023181:c394864-394337 [Paraburkholderia sp. PGU19]
ATGATCCTGACGCACCTGCCGGCGGGTACTATGCTTTACCGCGCACATGCACCCCGGTGGGCCAGCCGGCCGGCCAGTGG
AGCGGGCGCCGCAGCCAAGGGCGGGCGCTTCAACCGCGAAGGTATCGAGGCACTGTACTTGTCGCTGGAAGAACTGACAG
CTCTGCGCGAGTACCAGCAGACCTCGCCCTTCCTGCCACCCTGCACGGTCTGCTCCTACACCGTCGCGCTGCGTAATCTG
GTCGACCTGCGGCAACTCCACCGCGATCCTCTTTGGGACGACCTTTGGCACGACTGGCGCGAGGATTGGCGGCACCTGAA
ATTCGAGCTGCACATCGAGCCCCCGACCTGGGTTCTCAGTGACATGGTTCGGGAGCAGGGCTTTACCGGCATTGTGTTTC
CCAGCCAAACCCACGAGAGAGGTACAAACGTCGTGGTGTTTACCGACCGCCTCGGCGATGGCAATTCGATCGAGGTCAAC
GACCCGGATGGCCAACTTCCGCGGGACCAGGCAAGTTGGCCGCGTTGA

Antitoxin

Protein

• Length: 124 a.a.
• Molecular weight: 13414.33 Da
• Isoelectric Point: 6.7254

>AT36763 WP_180734490.1 NZ_AP023181:c395232-394861 [Paraburkholderia sp. PGU19]
MSAIAFADVLESAREAGTSRLSAANLANVLGLQQQDLATLAGVHRNTLRTHPESPKLQSTMRDLMRVLSAAVAVQPDFER
ALFLVKNQPIPTFRHKTILQLLQDGRTEDAIDYLESISAGFVG

Nucleotide

• Length: 372 bp

>AT36763 NZ_AP023181:c395232-394861 [Paraburkholderia sp. PGU19]
ATGAGCGCCATTGCATTTGCCGACGTGCTTGAGTCCGCGCGTGAAGCGGGAACGTCCCGTCTATCCGCCGCGAACCTCGC
CAACGTCTTGGGCTTGCAGCAGCAAGACCTGGCAACCTTGGCGGGTGTTCATCGCAACACGCTGCGCACCCATCCTGAGT
CGCCAAAACTCCAGTCCACCATGCGCGACCTCATGCGCGTGCTGTCGGCAGCTGTGGCGGTACAGCCGGACTTCGAGCGA
GCGCTGTTTCTGGTCAAGAACCAGCCCATCCCCACGTTTCGCCACAAGACTATCCTGCAACTGCTCCAGGATGGGCGGAC
TGAGGATGCGATCGACTATCTGGAGTCGATCAGCGCAGGATTTGTTGGATGA