Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1830925..1831070 Replicon chromosome
Accession NZ_AP023148
Organism Klebsiella pneumoniae strain SMKP03

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1830961..1831063 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1830925..1831070 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SMKP03_RS08850 1826055..1828115 + 2061 WP_048289976.1 oligopeptidase B -
SMKP03_RS08855 1828119..1828778 - 660 WP_002911407.1 exodeoxyribonuclease X -
SMKP03_RS08860 1828857..1829087 - 231 WP_002911406.1 DNA polymerase III subunit theta -
SMKP03_RS08865 1829200..1829574 + 375 WP_004151448.1 CopC domain-containing protein YobA -
SMKP03_RS08870 1829578..1830447 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
SMKP03_RS08875 1830464..1830802 + 339 WP_016529031.1 YebY family protein -
- 1830925..1831070 - 146 - - Antitoxin
- 1830961..1831063 + 103 - - Toxin
SMKP03_RS08880 1831437..1831580 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
SMKP03_RS08885 1831685..1832653 - 969 WP_004151446.1 VirK/YbjX family protein -
SMKP03_RS08890 1832810..1833463 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
SMKP03_RS08895 1833460..1833651 - 192 WP_002911395.1 YebW family protein -
SMKP03_RS08900 1833749..1833988 - 240 WP_002911393.1 YebV family protein -
SMKP03_RS08905 1834104..1835537 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T36742 NZ_AP023148:1830961-1831063 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT36742 NZ_AP023148:c1831070-1830925 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References