Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 5012725..5013974 Replicon chromosome
Accession NZ_AP023081
Organism Pseudomonas solani strain Sm006

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PSm6_RS22920 Protein ID WP_021220929.1
Coordinates 5013396..5013974 (+) Length 193 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PSm6_RS22915 Protein ID WP_265168355.1
Coordinates 5012725..5013282 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSm6_RS22895 (PSm6_46030) 5008080..5008691 + 612 WP_265168351.1 LysE family transporter -
PSm6_RS22900 (PSm6_46040) 5008695..5010782 - 2088 WP_265168352.1 ATP-binding protein -
PSm6_RS22905 (PSm6_46050) 5010970..5011725 + 756 WP_265168353.1 NAD-dependent deacylase -
PSm6_RS22910 (PSm6_46060) 5011754..5012269 - 516 WP_265168354.1 thioredoxin family protein -
PSm6_RS22915 (PSm6_46070) 5012725..5013282 + 558 WP_265168355.1 helix-turn-helix transcriptional regulator Antitoxin
PSm6_RS22920 (PSm6_46080) 5013396..5013974 + 579 WP_021220929.1 HD domain-containing protein Toxin
PSm6_RS22925 (PSm6_46090) 5014161..5014544 + 384 WP_031288275.1 cytochrome c -
PSm6_RS22930 5014581..5014721 - 141 WP_184491268.1 DUF2256 domain-containing protein -
PSm6_RS22935 (PSm6_46100) 5014718..5016259 - 1542 WP_265168356.1 cryptochrome/photolyase family protein -
PSm6_RS22940 (PSm6_46110) 5016256..5016561 - 306 WP_021220926.1 DUF6482 family protein -
PSm6_RS22945 (PSm6_46120) 5016592..5017128 - 537 WP_043247011.1 DUF3833 domain-containing protein -
PSm6_RS22950 (PSm6_46130) 5017140..5017691 - 552 WP_043246994.1 chalcone isomerase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-166)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 193 a.a.        Molecular weight: 21341.99 Da        Isoelectric Point: 4.6753

>T36732 WP_021220929.1 NZ_AP023081:5013396-5013974 [Pseudomonas solani]
MNIDRIKGRLDFLREAERLKDVLRSAHTSSGRAESTAEHSWRLCLMAITFADELVGLDLLRVLKMCVVHDLGEAIHGDIP
AIEQGGHPDKGAQEREDLLTLTRTLDAGLRDEILALWDDYENAASPEALAVKALDKLETLLQHNQGANPADFDYAFNLGY
GRRYTSGEPLFAAIREQLDAGTRQRMEAQAGE

Download         Length: 579 bp

>T36732 NZ_AP023081:5013396-5013974 [Pseudomonas solani]
ATGAACATCGACAGGATCAAGGGACGGCTCGACTTCCTCCGCGAGGCGGAGCGCCTCAAGGACGTGCTGCGCAGCGCCCA
CACCTCCAGCGGGCGCGCGGAAAGCACCGCCGAACACAGCTGGCGCCTGTGCCTGATGGCCATCACTTTCGCCGATGAGC
TGGTCGGGCTCGACCTGCTGCGGGTGCTGAAGATGTGCGTGGTCCATGACCTGGGCGAAGCCATCCACGGCGATATCCCC
GCCATCGAGCAGGGCGGCCATCCCGACAAGGGCGCCCAGGAGCGCGAAGACCTGCTGACCCTGACCCGCACCCTCGATGC
CGGGCTGCGCGACGAGATTCTCGCGCTGTGGGATGACTACGAGAACGCCGCCTCCCCCGAGGCGCTGGCGGTCAAGGCGC
TGGACAAGCTGGAGACCCTGCTGCAGCACAACCAGGGCGCCAACCCGGCGGACTTCGACTACGCCTTCAACCTCGGCTAC
GGGCGCCGCTACACCAGCGGCGAGCCCCTGTTCGCGGCCATTCGCGAGCAGCTGGACGCAGGCACGCGGCAGCGCATGGA
AGCCCAGGCGGGCGAGTAG

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20363.57 Da        Isoelectric Point: 8.7936

>AT36732 WP_265168355.1 NZ_AP023081:5012725-5013282 [Pseudomonas solani]
MNDSLLKPAVLGVALRRWRLLHRVKQAHAAQLFSVAQSTISRWESGVQEMEPAERARVEQMLAARLEAAADQALARLVSD
SPRAVHLVCDLSHRLLACSATRAAEFSVPLAELMGRSLWRYATPEIARKEAALDALGWRDLLMPPALEFGSGANDSAIVP
IRQGLCRWTRMTLSDGTAARLVETL

Download         Length: 558 bp

>AT36732 NZ_AP023081:5012725-5013282 [Pseudomonas solani]
ATGAACGACAGCCTTCTGAAACCGGCCGTGCTCGGCGTCGCGCTGCGGCGTTGGCGCCTGCTGCATCGGGTCAAGCAGGC
CCATGCGGCGCAGCTGTTCAGCGTGGCGCAATCGACCATCTCGCGTTGGGAAAGCGGCGTGCAGGAGATGGAGCCCGCCG
AGCGGGCGCGGGTGGAGCAGATGCTGGCCGCCCGGCTGGAGGCCGCAGCCGACCAGGCCCTGGCGCGGCTGGTGAGCGAC
AGCCCGCGCGCCGTGCACCTGGTCTGCGACCTCAGCCACCGCCTGCTGGCCTGTTCCGCCACCCGCGCCGCCGAGTTCTC
CGTGCCCCTGGCCGAGCTGATGGGGCGCTCGCTGTGGCGCTACGCAACGCCGGAGATCGCGCGCAAGGAAGCCGCCCTGG
ATGCCCTGGGCTGGCGCGACCTGCTGATGCCGCCGGCGCTGGAGTTCGGCAGCGGCGCCAATGATTCCGCCATCGTGCCC
ATCCGCCAGGGCCTGTGCCGCTGGACGCGCATGACCCTCTCCGACGGCACCGCCGCGCGCCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References