Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 643909..645069 Replicon chromosome
Accession NZ_AP023081
Organism Pseudomonas solani strain Sm006

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag PSm6_RS02995 Protein ID WP_265169504.1
Coordinates 643909..644661 (-) Length 251 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag PSm6_RS03000 Protein ID WP_021221398.1
Coordinates 644698..645069 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSm6_RS02975 (PSm6_05960) 639618..640502 + 885 WP_043243092.1 metal-dependent hydrolase -
PSm6_RS02980 (PSm6_05970) 640558..641919 - 1362 WP_265170496.1 DNA recombination protein RmuC -
PSm6_RS02985 (PSm6_05980) 642086..642493 - 408 WP_265169502.1 sel1 repeat family protein -
PSm6_RS02990 (PSm6_05990) 642842..643897 - 1056 WP_265169503.1 AraC family transcriptional regulator -
PSm6_RS02995 (PSm6_06000) 643909..644661 - 753 WP_265169504.1 RES family NAD+ phosphorylase Toxin
PSm6_RS03000 (PSm6_06010) 644698..645069 - 372 WP_021221398.1 DUF2384 domain-containing protein Antitoxin
PSm6_RS03005 (PSm6_06020) 645193..645675 + 483 WP_021221399.1 hypothetical protein -
PSm6_RS03010 (PSm6_06030) 645727..646128 + 402 WP_265169506.1 hypothetical protein -
PSm6_RS03015 646318..646503 + 186 WP_081672335.1 hypothetical protein -
PSm6_RS03020 (PSm6_06040) 646521..646967 - 447 WP_265169509.1 S24 family peptidase -
PSm6_RS03025 (PSm6_06050) 647070..648668 - 1599 WP_021221402.1 M28 family metallopeptidase -
PSm6_RS03030 (PSm6_06060) 649177..649728 + 552 WP_052351330.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(58-206)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(72-121)


Sequences

Toxin        


Download         Length: 251 a.a.        Molecular weight: 28315.31 Da        Isoelectric Point: 6.6435

>T36729 WP_265169504.1 NZ_AP023081:c644661-643909 [Pseudomonas solani]
MDIWTTCQGPERIRPLRGRLVRLVESQEQVATLQLVDNLAEQALLEELIETSKPPLPRSAEPLHYLLKTPFRYPPLRWGS
RFGTVHEPSLFYAASRLETAMAEGAFYRFVLWSGMAVPPPSGRILSEHSSFEARFQVERGVQLQLPPFDAHDEALADPVD
YRTSQALGAAMRAAGVEAFEYRSARCPLQGTNIALFTPEAFTERRPRNLTPWFCETTAEYVAFKHAQAPDTPRLFRMTQF
LVDGRLPQPA

Download         Length: 753 bp

>T36729 NZ_AP023081:c644661-643909 [Pseudomonas solani]
ATGGATATCTGGACGACCTGCCAAGGCCCGGAACGGATCAGGCCCTTGCGTGGCCGCCTGGTGCGCCTGGTGGAGAGCCA
GGAGCAGGTGGCCACCCTGCAACTGGTGGACAACCTCGCCGAGCAGGCGTTGCTGGAGGAACTCATCGAGACCAGCAAGC
CGCCACTGCCCCGCAGCGCCGAACCGCTGCACTACCTGCTGAAGACCCCGTTCCGCTACCCGCCGCTGCGCTGGGGATCG
CGCTTCGGCACCGTTCACGAGCCCAGCCTGTTCTATGCCGCATCACGCCTGGAAACCGCCATGGCCGAGGGGGCCTTCTA
CCGCTTCGTGCTGTGGAGCGGCATGGCGGTGCCGCCGCCCAGCGGGCGCATCCTGTCCGAGCATTCGTCCTTCGAGGCGC
GCTTCCAGGTCGAGCGCGGTGTACAGCTGCAATTGCCGCCTTTCGATGCCCACGACGAAGCACTCGCCGACCCGGTGGAC
TACCGCACCAGCCAGGCGCTGGGTGCCGCCATGCGCGCTGCGGGGGTCGAGGCCTTCGAGTACCGCTCCGCGCGTTGTCC
GTTGCAGGGCACCAATATCGCCCTGTTCACCCCTGAAGCCTTCACCGAGCGGCGGCCGCGCAATCTCACGCCTTGGTTCT
GCGAAACCACGGCCGAATACGTCGCCTTCAAGCATGCCCAGGCACCGGACACACCGCGCCTGTTCCGCATGACCCAGTTC
CTCGTCGACGGTCGTTTGCCGCAGCCGGCATGA

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13584.81 Da        Isoelectric Point: 10.2920

>AT36729 WP_021221398.1 NZ_AP023081:c645069-644698 [Pseudomonas solani]
MSALSRPTLDPDAVLAKALLNTREQLGLTQQQLADIVGVHRTAITRWADSGGIRPQSKTGELALLLIRAYRALFALFGGN
LDDMRHFLRTENRHLGAVPLELMAQVQGLVRVVEYLDAIRGKI

Download         Length: 372 bp

>AT36729 NZ_AP023081:c645069-644698 [Pseudomonas solani]
ATGAGCGCCCTCAGCCGCCCCACCCTCGATCCCGATGCCGTATTGGCCAAAGCACTGCTCAATACCCGTGAGCAACTGGG
GCTGACCCAGCAGCAACTGGCCGACATCGTCGGGGTGCACCGTACCGCCATCACCCGCTGGGCGGACAGCGGCGGCATCC
GCCCACAGAGCAAGACCGGCGAGCTGGCGCTGCTGCTGATCCGCGCCTACCGCGCCCTGTTCGCCCTGTTCGGCGGCAAC
CTCGACGACATGCGCCATTTCCTGCGCACCGAGAACCGCCACCTGGGTGCCGTGCCCCTCGAACTGATGGCCCAGGTGCA
GGGGCTGGTAAGGGTGGTGGAGTATCTGGACGCCATCCGCGGCAAGATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References