Detailed information of TA system TA036716

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 453860..454513
• Replicon: chromosome
• Accession: NZ_AP023077
• Organism: Acinetobacter baumannii strain OCU_Ac16a

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: OCUAC_RS02215
• Protein ID: WP_025469673.1
• Coordinates: 454124..454513 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: OCUAC_RS02210
• Protein ID: WP_072688898.1
• Coordinates: 453860..454117 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCUAC_RS02190	449375..450382	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
OCUAC_RS02195	450401..450778	+	378	WP_001216380.1	50S ribosomal protein L17	-
OCUAC_RS02200	450960..452450	+	1491	WP_072688900.1	NAD(P)/FAD-dependent oxidoreductase	-
OCUAC_RS02205	452500..453672	-	1173	WP_001190547.1	acyl-CoA dehydrogenase family protein	-
OCUAC_RS02210	453860..454117	+	258	WP_072688898.1	succinate dehydrogenase assembly factor 2	Antitoxin
OCUAC_RS02215	454124..454513	+	390	WP_025469673.1	membrane protein	Toxin
OCUAC_RS02220	455283..456368	+	1086	WP_000049106.1	hypothetical protein	-
OCUAC_RS02225	456446..457012	+	567	WP_000651536.1	rhombosortase	-
OCUAC_RS02230	457200..459395	+	2196	WP_001158905.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15662.98 Da
• Isoelectric Point: 10.4623

>T36716 WP_025469673.1 NZ_AP023077:454124-454513 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKKLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T36716 NZ_AP023077:454124-454513 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATCATTCACAGAACACCATT
TCTCGCGTCAAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAAAACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10330.82 Da
• Isoelectric Point: 4.6150

>AT36716 WP_072688898.1 NZ_AP023077:453860-454117 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRIELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT36716 NZ_AP023077:453860-454117 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCATTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTCGATTGGTTTATGGAAGTATCGGAACCACCACGTATCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTCCATGGTTAA