Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 453860..454513 Replicon chromosome
Accession NZ_AP023077
Organism Acinetobacter baumannii strain OCU_Ac16a

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OCUAC_RS02215 Protein ID WP_025469673.1
Coordinates 454124..454513 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag OCUAC_RS02210 Protein ID WP_072688898.1
Coordinates 453860..454117 (+) Length 86 a.a.

Genomic Context

OCUAC_RS02190OCUAC_RS02195OCUAC_RS02200OCUAC_RS02210OCUAC_RS02215OCUAC_RS02220OCUAC_RS02225OCUAC_RS02230OCUAC_RS02205
Location: 449375..450382 (1008 bp)
Type: Others
Protein ID: WP_000198631.1
Location: 450401..450778 (378 bp)
Type: Others
Protein ID: WP_001216380.1
Location: 450960..452450 (1491 bp)
Type: Others
Protein ID: WP_072688900.1
Location: 453860..454117 (258 bp)
Type: Antitoxin
Protein ID: WP_072688898.1
Location: 454124..454513 (390 bp)
Type: Toxin
Protein ID: WP_025469673.1
Location: 455283..456368 (1086 bp)
Type: Others
Protein ID: WP_000049106.1
Location: 456446..457012 (567 bp)
Type: Others
Protein ID: WP_000651536.1
Location: 457200..459395 (2196 bp)
Type: Others
Protein ID: WP_001158905.1
Location: 452500..453672 (1173 bp)
Type: Others
Protein ID: WP_001190547.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OCUAC_RS02190449375..450382+1008WP_000198631.1DNA-directed RNA polymerase subunit alpha-
OCUAC_RS02195450401..450778+378WP_001216380.150S ribosomal protein L17-
OCUAC_RS02200450960..452450+1491WP_072688900.1NAD(P)/FAD-dependent oxidoreductase-
OCUAC_RS02205452500..453672-1173WP_001190547.1acyl-CoA dehydrogenase family protein-
OCUAC_RS02210453860..454117+258WP_072688898.1succinate dehydrogenase assembly factor 2Antitoxin
OCUAC_RS02215454124..454513+390WP_025469673.1membrane proteinToxin
OCUAC_RS02220455283..456368+1086WP_000049106.1hypothetical protein-
OCUAC_RS02225456446..457012+567WP_000651536.1rhombosortase-
OCUAC_RS02230457200..459395+2196WP_001158905.1TRAP transporter large permease subunit-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15662.98 Da        Isoelectric Point: 10.4623

>T36716 WP_025469673.1 NZ_AP023077:454124-454513 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKKLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T36716 NZ_AP023077:454124-454513 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATCATTCACAGAACACCATT
TCTCGCGTCAAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAAAACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10330.82 Da        Isoelectric Point: 4.6150

>AT36716 WP_072688898.1 NZ_AP023077:453860-454117 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRIELRDFIYKLK
HYVHG

Download         Length: 258 bp

>AT36716 NZ_AP023077:453860-454117 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCATTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTCGATTGGTTTATGGAAGTATCGGAACCACCACGTATCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTCCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References