Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1621866..1622376 Replicon chromosome
Accession NZ_AP023063
Organism Nitratiruptor sp. YY08-26

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag JG738_RS08730 Protein ID WP_201337530.1
Coordinates 1622104..1622376 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag JG738_RS08725 Protein ID WP_197685259.1
Coordinates 1621866..1622123 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG738_RS08690 1617250..1617486 - 237 WP_084274677.1 acyl carrier protein -
JG738_RS08695 1617543..1618286 - 744 WP_201337525.1 3-oxoacyl-ACP reductase FabG -
JG738_RS08700 1618364..1619428 + 1065 WP_201337526.1 phospho-N-acetylmuramoyl-pentapeptide- transferase -
JG738_RS08705 1619428..1620609 + 1182 WP_201337527.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
JG738_RS08715 1620949..1621143 - 195 WP_201337528.1 hypothetical protein -
JG738_RS08720 1621322..1621468 + 147 WP_201337529.1 hypothetical protein -
JG738_RS08725 1621866..1622123 - 258 WP_197685259.1 hypothetical protein Antitoxin
JG738_RS08730 1622104..1622376 - 273 WP_201337530.1 BrnT family toxin Toxin
JG738_RS08735 1622818..1622973 - 156 WP_201337531.1 hypothetical protein -
JG738_RS08740 1623079..1623216 - 138 WP_201337532.1 hypothetical protein -
JG738_RS08745 1623738..1624937 + 1200 WP_201337533.1 amidohydrolase -
JG738_RS08750 1624927..1626387 + 1461 WP_201337534.1 GNAT family N-acetyltransferase -
JG738_RS08755 1626525..1626977 - 453 WP_201337535.1 DUF3368 domain-containing protein -
JG738_RS08760 1626977..1627300 - 324 WP_201337536.1 UPF0175 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-81)

Antitoxin

CopG antitoxin

(10-75)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10530.79 Da        Isoelectric Point: 5.7558

>T36701 WP_201337530.1 NZ_AP023063:c1622376-1622104 [Nitratiruptor sp. YY08-26]
VHIEYDPNKSKANKQKHGVDFEEAKALFENDDSLIVPAKIIDGEERYALIGYLDGKCYVAIFTYRGENIRIISVRRCRKN
EERNYEEYNG

Download         Length: 273 bp

>T36701 NZ_AP023063:c1622376-1622104 [Nitratiruptor sp. YY08-26]
GTGCATATCGAATACGATCCAAACAAAAGCAAAGCCAATAAGCAAAAGCATGGCGTAGACTTTGAGGAGGCTAAAGCGCT
CTTTGAAAATGACGACTCACTCATCGTGCCAGCCAAGATTATTGATGGCGAGGAGCGATATGCGCTTATCGGCTATCTCG
ATGGCAAGTGCTATGTTGCAATATTCACCTATAGAGGTGAAAACATCAGGATCATAAGTGTGAGAAGATGTAGAAAAAAC
GAGGAGAGAAACTATGAAGAGTATAACGGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9784.38 Da        Isoelectric Point: 8.5043

>AT36701 WP_197685259.1 NZ_AP023063:c1622123-1621866 [Nitratiruptor sp. YY08-26]
MKSITAKEFDEKFDRGEDISEYLDFGKAKRVGEVKKQPTKKINIDLPQNILNLIDEEASKIGVARQALLKVWIVERLKEE
LSKPL

Download         Length: 258 bp

>AT36701 NZ_AP023063:c1622123-1621866 [Nitratiruptor sp. YY08-26]
ATGAAGAGTATAACGGCTAAAGAGTTTGATGAGAAGTTTGATAGAGGCGAAGATATAAGTGAGTATCTTGATTTTGGTAA
GGCTAAAAGAGTAGGAGAAGTTAAAAAGCAGCCTACCAAAAAGATAAATATTGACCTACCTCAAAACATCCTCAATCTCA
TCGATGAGGAAGCAAGTAAAATAGGAGTGGCGAGGCAGGCACTGCTGAAGGTGTGGATAGTGGAGAGGCTCAAAGAGGAA
CTATCCAAGCCATTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References