Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 868620..869083 Replicon chromosome
Accession NZ_AP023063
Organism Nitratiruptor sp. YY08-26

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JG738_RS04735 Protein ID WP_201338723.1
Coordinates 868620..868832 (-) Length 71 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag JG738_RS04740 Protein ID WP_201338606.1
Coordinates 868874..869083 (-) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG738_RS04715 863742..864434 + 693 WP_201338602.1 WecB/TagA/CpsF family glycosyltransferase -
JG738_RS04720 864417..867137 - 2721 WP_201338603.1 O-antigen ligase family protein -
JG738_RS04725 867248..867556 + 309 WP_201338604.1 hypothetical protein -
JG738_RS04730 867546..867971 + 426 WP_201338605.1 PIN domain-containing protein -
JG738_RS04735 868620..868832 - 213 WP_201338723.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JG738_RS04740 868874..869083 - 210 WP_201338606.1 ribbon-helix-helix domain-containing protein Antitoxin
JG738_RS04745 869274..869645 + 372 WP_201340475.1 nucleotidyltransferase domain-containing protein -
JG738_RS04750 869599..870024 + 426 WP_201338608.1 DUF86 domain-containing protein -
JG738_RS04755 870162..870392 + 231 WP_201338609.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
JG738_RS04760 870389..870724 + 336 WP_201338610.1 endoribonuclease MazF -
JG738_RS04765 870951..871235 + 285 WP_201338611.1 nucleotidyltransferase domain-containing protein -
JG738_RS04770 871232..871672 + 441 WP_201338612.1 hypothetical protein -
JG738_RS04775 871832..872002 + 171 WP_201338613.1 hypothetical protein -
JG738_RS04780 871944..873014 + 1071 WP_201338614.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-67)

Antitoxin

Ribbon-helix-helix protein, CopG

(2-38)


Sequences

Toxin        


Download         Length: 71 a.a.        Molecular weight: 8338.66 Da        Isoelectric Point: 9.2779

>T36699 WP_201338723.1 NZ_AP023063:c868832-868620 [Nitratiruptor sp. YY08-26]
INKKDQIKIIDTIENRLAINPYSGKKLAGSLSDFYRYRVEKYHIIYSIHESNIEIEIIKIGHRKDIYDLM

Download         Length: 213 bp

>T36699 NZ_AP023063:c868832-868620 [Nitratiruptor sp. YY08-26]
ATAAATAAAAAAGATCAGATTAAAATTATCGATACTATCGAAAATAGGCTCGCCATCAATCCCTATTCTGGGAAAAAATT
AGCCGGTAGTCTTTCTGATTTTTATAGATATCGTGTGGAAAAATATCATATAATTTATAGTATTCATGAATCAAATATAG
AAATAGAAATTATAAAGATCGGACATAGGAAAGATATTTACGATTTGATGTAG

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 8196.58 Da        Isoelectric Point: 4.8896

>AT36699 WP_201338606.1 NZ_AP023063:c869083-868874 [Nitratiruptor sp. YY08-26]
MLTVRLDKELEQKLEKLAILTKRPKSFFVKEALRQYLEDIEDILDAKERVNDPAKELITLDELKRELNV

Download         Length: 210 bp

>AT36699 NZ_AP023063:c869083-868874 [Nitratiruptor sp. YY08-26]
ATGCTTACCGTTCGACTCGATAAAGAACTTGAACAAAAGTTAGAAAAATTAGCCATTTTGACCAAGCGGCCAAAAAGTTT
TTTTGTCAAAGAAGCACTTCGCCAATATCTCGAAGATATTGAGGATATCTTAGACGCTAAAGAAAGAGTAAACGATCCAG
CAAAAGAACTCATTACTTTAGATGAGCTCAAAAGAGAACTGAATGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References