Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 989984..990529 Replicon chromosome
Accession NZ_AP023055
Organism Thaumasiovibrio subtropicus strain C4V358

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag TSUB_RS20835 Protein ID WP_087023755.1
Coordinates 990233..990529 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag TSUB_RS20830 Protein ID WP_087023757.1
Coordinates 989984..990226 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TSUB_RS20805 985200..985745 - 546 WP_159065065.1 hypothetical protein -
TSUB_RS20810 986826..987928 - 1103 Protein_904 ISAs1 family transposase -
TSUB_RS20815 988042..988221 - 180 WP_087024803.1 hypothetical protein -
TSUB_RS20820 988519..989007 + 489 WP_087024802.1 hypothetical protein -
TSUB_RS20825 989720..989890 + 171 Protein_907 IS110 family transposase -
TSUB_RS20830 989984..990226 + 243 WP_087023757.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
TSUB_RS20835 990233..990529 + 297 WP_087023755.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
TSUB_RS20840 991004..991636 - 633 WP_159064971.1 papain-like cysteine protease family protein -
TSUB_RS20845 991997..992458 - 462 WP_087023751.1 acyltransferase -
TSUB_RS20850 992500..993327 - 828 WP_159064970.1 alpha/beta hydrolase -
TSUB_RS20855 993636..994274 + 639 WP_087023747.1 hypothetical protein -
TSUB_RS20860 994340..995503 - 1164 WP_087023745.1 YibE/F family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-49)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11273.91 Da        Isoelectric Point: 10.1026

>T36691 WP_087023755.1 NZ_AP023055:990233-990529 [Thaumasiovibrio subtropicus]
MQKNRYKLSKLAQAHLRKIKSYTVNNYSETQWHTYKNKLLTGFQMLADNPAVGRSCNEIYPSGFYFSVGKHTAYFTKEDG
FILVVAVLGQSQLPQNHL

Download         Length: 297 bp

>T36691 NZ_AP023055:990233-990529 [Thaumasiovibrio subtropicus]
ATGCAAAAGAATAGATACAAACTGAGTAAATTAGCTCAGGCTCATTTAAGAAAAATTAAGAGCTATACTGTCAACAATTA
CTCTGAAACTCAGTGGCACACCTACAAAAATAAGCTATTAACCGGATTTCAAATGCTTGCCGACAATCCAGCCGTAGGTC
GCAGCTGCAATGAAATTTATCCAAGTGGTTTTTACTTTTCTGTGGGCAAACACACAGCCTACTTTACTAAGGAAGACGGC
TTCATTTTAGTTGTCGCTGTACTCGGCCAATCGCAACTCCCACAAAACCATTTATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8906.09 Da        Isoelectric Point: 4.8000

>AT36691 WP_087023757.1 NZ_AP023055:989984-990226 [Thaumasiovibrio subtropicus]
MHTLTANDAKRNFGELLLSAQREPVKISKNSKDVVVVMSIKDYEELEAMKAEHIKHCFESATQDLAQGNVVDGEDFLSAL

Download         Length: 243 bp

>AT36691 NZ_AP023055:989984-990226 [Thaumasiovibrio subtropicus]
ATGCATACATTAACAGCAAATGATGCTAAACGTAATTTTGGTGAGCTACTCCTTAGCGCCCAACGTGAACCAGTGAAGAT
TAGCAAAAATAGTAAAGATGTCGTAGTAGTCATGTCTATCAAGGACTACGAGGAGCTGGAGGCAATGAAAGCTGAACACA
TCAAACATTGTTTCGAGTCAGCCACACAAGACTTAGCACAAGGCAATGTTGTTGATGGTGAGGATTTTTTAAGCGCCTTA
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References