Detailed information of TA system TA036690

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 982634..983199
• Replicon: chromosome
• Accession: NZ_AP023055
• Organism: Thaumasiovibrio subtropicus strain C4V358

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: TSUB_RS20790
• Protein ID: WP_087016513.1
• Coordinates: 982634..982921 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: TSUB_RS20795
• Protein ID: WP_087016512.1
• Coordinates: 982918..983199 (-)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
TSUB_RS20760	977770..977952	-	183	WP_087016518.1	hypothetical protein	-
TSUB_RS20765	977945..978664	-	720	WP_087016517.1	response regulator transcription factor	-
TSUB_RS20770	978732..979013	-	282	WP_087016516.1	single-stranded DNA-binding protein	-
TSUB_RS20775	979040..980182	-	1143	WP_087016515.1	phage/plasmid replication protein, II/X family	-
TSUB_RS20780	980308..980835	+	528	WP_246616469.1	helix-turn-helix transcriptional regulator	-
TSUB_RS20785	981908..982126	-	219	WP_087016514.1	hypothetical protein	-
TSUB_RS25110	982418..982597	+	180	Protein_898	IS110 family transposase	-
TSUB_RS20790	982634..982921	-	288	WP_087016513.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
TSUB_RS20795	982918..983199	-	282	WP_087016512.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
TSUB_RS25115	983495..983842	+	348	Protein_901	IS110 family transposase	-
TSUB_RS20800	983946..985093	+	1148	WP_221274594.1	IS3 family transposase	-
TSUB_RS20805	985200..985745	-	546	WP_159065065.1	hypothetical protein	-
TSUB_RS20810	986826..987928	-	1103	Protein_904	ISAs1 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	960529..985093	24564

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-74)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11027.74 Da
• Isoelectric Point: 5.0746

>T36690 WP_087016513.1 NZ_AP023055:c982921-982634 [Thaumasiovibrio subtropicus]
MKVVWSPLALQKLGDAAEFIAMDNPVAAENWVNEVFDKTDLLSSMPEMGRMVPELPHTNYREILFGHYRIIYSFTHEIRV
LTVRNCRQMLTESDV

Nucleotide

• Length: 288 bp

>T36690 NZ_AP023055:c982921-982634 [Thaumasiovibrio subtropicus]
ATGAAAGTGGTCTGGTCACCACTAGCATTGCAAAAGTTAGGTGATGCAGCTGAGTTTATTGCAATGGATAATCCAGTCGC
AGCAGAGAACTGGGTTAACGAGGTTTTCGATAAAACTGATCTGCTCTCGAGTATGCCTGAAATGGGGCGAATGGTTCCTG
AGCTGCCTCATACCAATTATCGTGAAATCTTGTTTGGTCACTATAGAATCATTTATAGCTTCACTCATGAAATTCGTGTT
CTTACAGTTCGAAATTGTCGTCAAATGCTAACGGAGAGTGACGTGTAG

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10616.17 Da
• Isoelectric Point: 4.9011

>AT36690 WP_087016512.1 NZ_AP023055:c983199-982918 [Thaumasiovibrio subtropicus]
MSRIRFDQDIQPLSEFRAGVTSFIRQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRIAEAQLASDLGVSN
EDARAQVLERIKK

Nucleotide

• Length: 282 bp

>AT36690 NZ_AP023055:c983199-982918 [Thaumasiovibrio subtropicus]
ATGAGCCGTATCCGCTTTGACCAAGATATTCAGCCTTTGTCTGAATTTCGTGCTGGCGTAACGTCATTTATTAGACAGAT
CAACGAAACTCGTAGACCACTAGTCATCACGCAACGTGGTAAAGGTGTTGCGGTTGTCCTTGATGTTGCGGAATATGAAG
CAATGCAAGAGAAAATTGAGCTACTGGAAGAAATGCGTATAGCTGAAGCACAGTTAGCTTCAGATTTAGGTGTTTCCAAT
GAAGACGCTCGTGCTCAAGTGTTGGAGCGTATTAAGAAATGA