Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 277791..278331 Replicon chromosome
Accession NZ_AP023055
Organism Thaumasiovibrio subtropicus strain C4V358

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag TSUB_RS17530 Protein ID WP_087018209.1
Coordinates 278062..278331 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag TSUB_RS17525 Protein ID WP_087018207.1
Coordinates 277791..278075 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TSUB_RS17490 273677..274684 + 1008 WP_087018194.1 substrate-binding domain-containing protein -
TSUB_RS17495 274817..275320 - 504 WP_087018196.1 hypothetical protein -
TSUB_RS17500 275835..276080 + 246 WP_087018200.1 type II toxin-antitoxin system CcdA family antitoxin -
TSUB_RS17505 276080..276397 + 318 WP_087018203.1 CcdB family protein -
TSUB_RS17510 276513..276679 + 167 Protein_241 IS110 family transposase -
TSUB_RS17515 276726..277175 - 450 WP_159064829.1 DUF4265 domain-containing protein -
TSUB_RS17520 277270..277437 + 168 Protein_243 IS110 family transposase -
TSUB_RS17525 277791..278075 + 285 WP_087018207.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
TSUB_RS17530 278062..278331 + 270 WP_087018209.1 type II toxin-antitoxin system YafQ family toxin Toxin
TSUB_RS17535 278433..278588 + 156 Protein_246 IS110 family transposase -
TSUB_RS25075 278880..279812 - 933 WP_087018213.1 SEC-C metal-binding domain-containing protein -
TSUB_RS17545 279927..280151 - 225 WP_087018215.1 hypothetical protein -
TSUB_RS17550 280407..280727 - 321 WP_087018217.1 hypothetical protein -
TSUB_RS17555 280987..281550 - 564 WP_087018219.1 hypothetical protein -
TSUB_RS17560 281717..282358 - 642 WP_087018221.1 Crp/Fnr family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-83)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10264.93 Da        Isoelectric Point: 9.5513

>T36689 WP_087018209.1 NZ_AP023055:278062-278331 [Thaumasiovibrio subtropicus]
MYLLEYSTQFKKDFKKVTKLPIPDVLEVGNIISKLQRGETLSAKNVDHPLSGNWAGFRDCHIKPDLVLIYRIHDRTLQLA
RIGSHSELF

Download         Length: 270 bp

>T36689 NZ_AP023055:278062-278331 [Thaumasiovibrio subtropicus]
ATGTATCTTCTTGAATACTCAACGCAATTCAAAAAAGACTTCAAGAAAGTTACTAAGCTGCCTATCCCTGATGTACTTGA
AGTAGGCAACATTATTTCTAAACTACAGCGTGGCGAAACACTTAGCGCTAAAAATGTTGACCATCCATTGAGTGGGAACT
GGGCTGGATTTAGAGACTGTCACATTAAGCCGGACTTAGTTCTAATCTATCGCATCCACGATAGAACTCTTCAACTAGCC
AGAATAGGCTCACACAGCGAACTTTTTTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10196.48 Da        Isoelectric Point: 5.5005

>AT36689 WP_087018207.1 NZ_AP023055:277791-278075 [Thaumasiovibrio subtropicus]
MKNEMLSTRIDHDTKVAFTNICDEVGLSPSQAIKLFAHAVINHGGIPFELKVKQPNQESIAAMQELVSGQGHKADSVDSL
FNTLTDDKVSNVSS

Download         Length: 285 bp

>AT36689 NZ_AP023055:277791-278075 [Thaumasiovibrio subtropicus]
ATGAAAAATGAAATGCTAAGTACACGTATCGACCACGATACCAAAGTAGCTTTTACCAACATCTGTGATGAAGTTGGTTT
GAGCCCCTCACAAGCCATTAAGCTGTTTGCTCACGCAGTGATCAATCACGGTGGAATTCCATTCGAGCTCAAAGTAAAAC
AGCCGAATCAAGAGAGCATTGCTGCAATGCAAGAATTAGTATCTGGCCAAGGCCATAAAGCTGACTCGGTCGACTCTCTG
TTCAATACACTAACCGATGACAAAGTAAGCAATGTATCTTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References