Detailed information of TA system TA036688

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 1872885..1873432
• Replicon: chromosome
• Accession: NZ_AP023054
• Organism: Thaumasiovibrio subtropicus strain C4V358

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: TSUB_RS08460
• Protein ID: WP_087025372.1
• Coordinates: 1872885..1873187 (-)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: TSUB_RS08465
• Protein ID: WP_087025375.1
• Coordinates: 1873175..1873432 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
TSUB_RS08425	1868011..1868706	-	696	WP_087025346.1	SDR family NAD(P)-dependent oxidoreductase	-
TSUB_RS08430	1869087..1869371	+	285	WP_087025350.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	-
TSUB_RS08435	1869368..1869646	+	279	WP_087025353.1	type II toxin-antitoxin system RelE/ParE family toxin	-
TSUB_RS08440	1869746..1870201	-	456	WP_087025356.1	macro domain-containing protein	-
TSUB_RS08445	1870564..1870890	-	327	WP_087025360.1	DUF2834 domain-containing protein	-
TSUB_RS08450	1871061..1871381	-	321	WP_087025363.1	hypothetical protein	-
TSUB_RS08455	1871883..1872377	-	495	WP_246616337.1	hypothetical protein	-
TSUB_RS25025	1872642..1872841	+	200	Protein_1647	IS110 family transposase	-
TSUB_RS08460	1872885..1873187	-	303	WP_087025372.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
TSUB_RS08465	1873175..1873432	-	258	WP_087025375.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
TSUB_RS08470	1873790..1873990	+	201	Protein_1650	IS110 family transposase	-
TSUB_RS08475	1874013..1874345	-	333	WP_087025378.1	hypothetical protein	-
TSUB_RS08480	1874642..1875744	-	1103	Protein_1652	ISAs1 family transposase	-
TSUB_RS08485	1875847..1876047	+	201	Protein_1653	IS110 family transposase	-
TSUB_RS08490	1876427..1877239	+	813	Protein_1654	IS110 family transposase	-
TSUB_RS08500	1877892..1878227	-	336	WP_159064854.1	transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-69)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11625.60 Da
• Isoelectric Point: 6.9790

>T36688 WP_087025372.1 NZ_AP023054:c1873187-1872885 [Thaumasiovibrio subtropicus]
MAEIIWTEPALSDLNDIAEYIALGNIAAAKQLVQTIFSKVERLQTFPESGRIPPELEHLTYREVVVNPCRVFYKQYGDKV
LILFVMRVERDLRKFLLSKQ

Nucleotide

• Length: 303 bp

>T36688 NZ_AP023054:c1873187-1872885 [Thaumasiovibrio subtropicus]
ATGGCTGAAATAATCTGGACTGAACCAGCGTTATCTGACCTCAACGATATCGCAGAATACATCGCACTTGGAAATATTGC
TGCTGCAAAGCAGTTAGTACAAACGATCTTCTCCAAAGTCGAACGTCTACAAACTTTCCCAGAGTCAGGTCGTATTCCAC
CTGAGCTAGAACATTTAACTTATCGTGAAGTTGTCGTTAATCCATGTCGTGTTTTCTATAAGCAATACGGTGACAAGGTG
CTTATTCTGTTTGTTATGCGTGTTGAGAGAGATTTGCGTAAGTTCCTGTTGAGTAAGCAGTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9634.11 Da
• Isoelectric Point: 6.7269

>AT36688 WP_087025375.1 NZ_AP023054:c1873432-1873175 [Thaumasiovibrio subtropicus]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDEAKDRM
SKWLK

Nucleotide

• Length: 258 bp

>AT36688 NZ_AP023054:c1873432-1873175 [Thaumasiovibrio subtropicus]
ATGAAAGTAGAACTAGTTACATCACTTAAACGCCAAGCGACCAAGATTCTCGCTGATCTCCACGACACCAAAGAACCAGT
GTTAATTACTGAGCATGGTAAGCCATCCGCGTATCTCGTTGATGTTGATGATTACGAATTTATGCAAAATCGTTTGGCTA
TTCTTGAGGGGATCGCACGAGGTGAACGCGCACTAGCTGACGGTAAAGTGGTAAGCCATGATGAAGCCAAAGACAGAATG
TCAAAATGGCTGAAATAA